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Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial.
Davies C, Pan H, Godwin J, Gray R, Arriagada R, Raina V, Abraham M, Medeiros Alencar VH, Badran A, Bonfill X, Bradbury J, Clarke M, Collins R, Davis SR, Delmestri A, Forbes JF, Haddad P, Hou MF, Inbar M, Khaled H, Kielanowska J, Kwan WH, Mathew BS, Mittra I, Müller B, Nicolucci A, Peralta O, Pernas F, Petruzelka L, Pienkowski T, Radhika R, Rajan B, Rubach MT, Tort S, Urrútia G, Valentini M, Wang Y, Peto R; Adjuvant Tamoxifen: Longer Against Shorter (ATLAS) Collaborative Group. Davies C, et al. Lancet. 2013 Mar 9;381(9869):805-16. doi: 10.1016/S0140-6736(12)61963-1. Lancet. 2013. PMID: 23219286 Free PMC article. Clinical Trial.
We report effects on breast cancer outcomes among the 6846 women with ER-positive disease, and side-effects among all women (with positive, negative, or unknown ER status). Long-term follow-up still continues. This study is registered, number ISRCTN19652633. ...
We report effects on breast cancer outcomes among the 6846 women with ER-positive disease, and side-effects among all women (with positive, …
Medical Treatment Failure for Symptomatic Vasospasm After Subarachnoid Hemorrhage Threatens Long-Term Outcome.
Suwatcharangkoon S, De Marchis GM, Witsch J, Meyers E, Velazquez A, Falo C, Schmidt JM, Agarwal S, Connolly ES, Claassen J, Mayer SA. Suwatcharangkoon S, et al. Among authors: falo c. Stroke. 2019 Jul;50(7):1696-1702. doi: 10.1161/STROKEAHA.118.022536. Epub 2019 Jun 5. Stroke. 2019. PMID: 31164068 Clinical Trial.
Background and Purpose- Symptomatic vasospasm is a common cause of morbidity and mortality after subarachnoid hemorrhage. We sought to identify predictors and the long-term impact of treatment failure with hypertensive therapy for symptomatic vasospasm. ...
Background and Purpose- Symptomatic vasospasm is a common cause of morbidity and mortality after subarachnoid hemorrhage. We sought to ident …
Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome.
Ziai WC, Thompson CB, Mayo S, McBee N, Freeman WD, Dlugash R, Ullman N, Hao Y, Lane K, Awad I, Hanley DF; Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III) Investigators. Ziai WC, et al. Crit Care Med. 2019 Aug;47(8):1125-1134. doi: 10.1097/CCM.0000000000003848. Crit Care Med. 2019. PMID: 31162192 Free PMC article. Clinical Trial.
CONCLUSIONS: Elevated intracranial pressure and inadequate cerebral perfusion pressure are not infrequent during extraventricular drainage for severe intraventricular hemorrhage, and level and duration predict higher short-term mortality and long-term mortality. Bur …
CONCLUSIONS: Elevated intracranial pressure and inadequate cerebral perfusion pressure are not infrequent during extraventricular drainage f …
Loss of Consciousness at Onset of Subarachnoid Hemorrhage as an Important Marker of Early Brain Injury.
Suwatcharangkoon S, Meyers E, Falo C, Schmidt JM, Agarwal S, Claassen J, Mayer SA. Suwatcharangkoon S, et al. Among authors: falo c. JAMA Neurol. 2016 Jan;73(1):28-35. doi: 10.1001/jamaneurol.2015.3188. JAMA Neurol. 2016. PMID: 26552033
OBJECTIVE: To clarify the association between LOC at onset of SAH, complications while in the hospital, and long-term outcome after SAH. DESIGN, SETTING, AND PARTICIPANTS: A retrospective analysis was conducted of 1460 consecutively treated patients with spontaneous SAH wh …
OBJECTIVE: To clarify the association between LOC at onset of SAH, complications while in the hospital, and long-term outcome after S …
Ultra-early angiographic vasospasm associated with delayed cerebral ischemia and infarction following aneurysmal subarachnoid hemorrhage.
Al-Mufti F, Roh D, Lahiri S, Meyers E, Witsch J, Frey HP, Dangayach N, Falo C, Mayer SA, Agarwal S, Park S, Meyers PM, Connolly ES, Claassen J, Schmidt JM. Al-Mufti F, et al. Among authors: falo c. J Neurosurg. 2017 May;126(5):1545-1551. doi: 10.3171/2016.2.JNS151939. Epub 2016 May 27. J Neurosurg. 2017. PMID: 27231975
These patients may benefit from earlier monitoring for signs of DCI and more aggressive treatment. Further study is needed to determine the long-term functional significance of UEAV....
These patients may benefit from earlier monitoring for signs of DCI and more aggressive treatment. Further study is needed to determine the …