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Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Sesso HD, Manson JE, Aragaki AK, Rist PM, Johnson LG, Friedenberg G, Copeland T, Clar A, Mora S, Moorthy MV, Sarkissian A, Carrick WR, Anderson GL; COSMOS Research Group. Sesso HD, et al. Am J Clin Nutr. 2022 Jun 7;115(6):1490-1500. doi: 10.1093/ajcn/nqac055. Am J Clin Nutr. 2022. PMID: 35294962 Free PMC article. Clinical Trial.
BACKGROUND: Cocoa extract is a source of flavanols that favorably influence vascular risk factors in small and short-term trials, yet effects on clinical cardiovascular events are untested. ...
BACKGROUND: Cocoa extract is a source of flavanols that favorably influence vascular risk factors in small and short-term trials, yet …
DMOG Negatively Impacts Tissue Engineered Cartilage Development.
Falcon JM, Chirman D, Veneziale A, Morman J, Bolten K, Kandel S, Querido W, Freeman T, Pleshko N. Falcon JM, et al. Cartilage. 2021 Dec;13(2_suppl):722S-733S. doi: 10.1177/1947603520967060. Epub 2020 Oct 26. Cartilage. 2021. PMID: 33100027 Free PMC article.
CONCLUSIONS: Despite previous studies that demonstrated the efficacy of DMOG, here, short-term treatment with DMOG did not have a uniformly positive impact on the chondrogenic capacity of SYN-MSCs in either pellet culture or in scaffold-based engineered cartilage, as evide …
CONCLUSIONS: Despite previous studies that demonstrated the efficacy of DMOG, here, short-term treatment with DMOG did not have a uni …
Restructuring of the 'Macaronesia' biogeographic unit: A marine multi-taxon biogeographical approach.
Freitas R, Romeiras M, Silva L, Cordeiro R, Madeira P, González JA, Wirtz P, Falcón JM, Brito A, Floeter SR, Afonso P, Porteiro F, Viera-Rodríguez MA, Neto AI, Haroun R, Farminhão JNM, Rebelo AC, Baptista L, Melo CS, Martínez A, Núñez J, Berning B, Johnson ME, Ávila SP. Freitas R, et al. Among authors: falcon jm. Sci Rep. 2019 Nov 5;9(1):15792. doi: 10.1038/s41598-019-51786-6. Sci Rep. 2019. PMID: 31690834 Free PMC article.
The Azores, Madeira, Selvagens, Canary Islands and Cabo Verde are commonly united under the term "Macaronesia". This study investigates the coherency and validity of Macaronesia as a biogeographic unit using six marine groups with very different dispersal abilities: coasta …
The Azores, Madeira, Selvagens, Canary Islands and Cabo Verde are commonly united under the term "Macaronesia". This study investigat …
Cochlear implants in adults over 60: a study of communicative benefits and the impact on quality of life.
Ramos A, Guerra-Jiménez G, Rodriguez C, Borkoski S, Falcón JC, Perez D. Ramos A, et al. Among authors: falcon jc. Cochlear Implants Int. 2013 Nov;14(5):241-5. doi: 10.1179/1754762812Y.0000000028. Epub 2013 Mar 18. Cochlear Implants Int. 2013. PMID: 23510755
CONCLUSIONS: Cochlear implantation improves QoL of patients over 60 by the mere fact of having been implanted, regardless of poorer audiological benefits. Older patients, with long-term deafness experience a greater improvement in QoL after implantation. ...
CONCLUSIONS: Cochlear implantation improves QoL of patients over 60 by the mere fact of having been implanted, regardless of poorer audiolog …
Continuous light and melatonin: daily and seasonal variations of brain binding sites and plasma concentration during the first reproductive cycle of sea bass.
Bayarri MJ, Falcón J, Zanuy S, Carrillo M. Bayarri MJ, et al. Among authors: falcon j. Gen Comp Endocrinol. 2010 Oct;169(1):58-64. doi: 10.1016/j.ygcen.2010.07.007. Epub 2010 Jul 27. Gen Comp Endocrinol. 2010. PMID: 20670627
Under LL, (1) plasma melatonin showed no elevation during the subjective night; and (2) Kd and Bmax exhibited seasonal variations in the hypothalamus. These results led to the conclusion that long-term exposure to LL affected both plasma melatonin and receptor oscillations …
Under LL, (1) plasma melatonin showed no elevation during the subjective night; and (2) Kd and Bmax exhibited seasonal variations in the hyp …
[Brain death in Ibero-America].
Escudero D, Matesanz R, Soratti CA, Flores JI; nombre de la Red/Consejo Iberoamericano de Donación y Trasplante. Escudero D, et al. Med Intensiva. 2009 Dec;33(9):415-23. doi: 10.1016/j.medin.2009.07.011. Med Intensiva. 2009. PMID: 19833413 Free article. Spanish.
OBJECTIVE: To examine the diagnosis of brain death (BD) in Latin America. BACKGROUND: The term BD has long been used to define the death of an individual despite legal differences and variations in the diagnostic criteria applied in each country. ...
OBJECTIVE: To examine the diagnosis of brain death (BD) in Latin America. BACKGROUND: The term BD has long been used to define the de …
The timing of the shrew: continuous melatonin treatment maintains youthful rhythmic activity in aging Crocidura russula.
Magnanou E, Attia J, Fons R, Boeuf G, Falcon J. Magnanou E, et al. Among authors: falcon j. PLoS One. 2009 Jun 15;4(6):e5904. doi: 10.1371/journal.pone.0005904. PLoS One. 2009. PMID: 19526053 Free PMC article.
This pattern was considerably delayed in melatonin-implanted shrews who maintained the daily rhythm for significantly longer. CONCLUSIONS: This is the first long term study (>500 days observation of the same individuals) that investigates the effects of continuous melat …
This pattern was considerably delayed in melatonin-implanted shrews who maintained the daily rhythm for significantly longer. CONCLUSIONS: T …
Differential expression and function of PACAP and VIP receptors in four human colonic adenocarcinoma cell lines.
Lelièvre V, Meunier AC, Caigneaux E, Falcon J, Muller JM. Lelièvre V, et al. Among authors: falcon j. Cell Signal. 1998 Jan;10(1):13-26. doi: 10.1016/s0898-6568(97)00067-3. Cell Signal. 1998. PMID: 9502113
Here, we confirm that high-affinity binding sites for the Vasoactive Intestinal Polypeptide (VIP) and for the VIP analogue Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP), were expressed in 4 human colonic adenocarcinoma cell lines, HT29, SW403, DLD-1 and Caco-2, that …
Here, we confirm that high-affinity binding sites for the Vasoactive Intestinal Polypeptide (VIP) and for the VIP analogue Pituitary Adenyla …
[Short-term prognosis in patients with congestive heart failure and normal left ventricular systolic function].
Roel JE, Bouza G, Lantos J, Cifre JR, Bruno C, Falcón JL. Roel JE, et al. Among authors: falcon jl. Medicina (B Aires). 1993;53(5):385-90. Medicina (B Aires). 1993. PMID: 8201925 Spanish.
The aims of this prospective assay are: to describe a group of 70 patients admitted to an internal medicine department with the clinical syndrome of CHF, to determine the contractile state of the left ventricle with echocardiography and to establish the short term prognosi …
The aims of this prospective assay are: to describe a group of 70 patients admitted to an internal medicine department with the clinical syn …
Pineal photoreceptor cells: photoperiodic control of melatonin production after cell dissociation and culture.
Bégay V, Falcón J, Thibault C, Ravault JP, Collin JP. Bégay V, et al. Among authors: falcon j. J Neuroendocrinol. 1992 Jun;4(3):337-45. doi: 10.1111/j.1365-2826.1992.tb00177.x. J Neuroendocrinol. 1992. PMID: 21554615
The profile of its rhythm and that of the activity of the hydroxyindole-O-methyltransferase-the last enzyme of the melatonin biosynthetic pathway-depended on the substrates and on the culture media used. Some of them appear suitable for short- or long-term culture of photo …
The profile of its rhythm and that of the activity of the hydroxyindole-O-methyltransferase-the last enzyme of the melatonin biosynthetic pa …
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