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2004 | 1 |
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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.
Science. 2004 Jul 16;305(5682):390-2. doi: 10.1126/science.1099196. Epub 2004 Jun 17.
Science. 2004.
PMID: 15205477
Thus, CR could extend life-span by inducing SIRT1 expression and promoting the long-term survival of irreplaceable cells....
Thus, CR could extend life-span by inducing SIRT1 expression and promoting the long-term survival of irreplaceable cells....
Small RNA: can RNA interference be exploited for therapy?
Wall NR, Shi Y.
Wall NR, et al.
Lancet. 2003 Oct 25;362(9393):1401-3. doi: 10.1016/S0140-6736(03)14637-5.
Lancet. 2003.
PMID: 14585643
Review.
Combined with genomics data, RNAi-directed gene-silencing could allow functional determination of any gene expressed in a cell or pathway. The term RNAi came from the discovery that the injection of dsRNAs into Caenorhabditis elegans interferes with the expression of speci …
Combined with genomics data, RNAi-directed gene-silencing could allow functional determination of any gene expressed in a cell or pathway. T …
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