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Outcomes associated with antibiotic regimens for treatment of Mycobacterium abscessus in cystic fibrosis patients.
DaCosta A, Jordan CL, Giddings O, Lin FC, Gilligan P, Esther CR Jr. DaCosta A, et al. Among authors: esther cr jr. J Cyst Fibros. 2017 Jul;16(4):483-487. doi: 10.1016/j.jcf.2017.04.013. Epub 2017 May 8. J Cyst Fibros. 2017. PMID: 28495380 Free article.
Antibiotic choices did not influence outcomes except for greater clearance with clarithromycin. CONCLUSIONS: Treatment of M. abscessus resulted in short term improvement in lung function that is inversely related to pre-treatment FEV(1)....
Antibiotic choices did not influence outcomes except for greater clearance with clarithromycin. CONCLUSIONS: Treatment of M. abscessus resul …
Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis.
Cholon DM, Quinney NL, Fulcher ML, Esther CR Jr, Das J, Dokholyan NV, Randell SH, Boucher RC, Gentzsch M. Cholon DM, et al. Among authors: esther cr jr. Sci Transl Med. 2014 Jul 23;6(246):246ra96. doi: 10.1126/scitranslmed.3008680. Sci Transl Med. 2014. PMID: 25101886 Free PMC article.
These findings demonstrate that chronic treatment with CFTR potentiators and correctors may have unexpected effects that cannot be predicted from short-term studies. Combining these drugs to maximize rescue of deltaF508 CFTR may require changes in dosing and/or development …
These findings demonstrate that chronic treatment with CFTR potentiators and correctors may have unexpected effects that cannot be predicted …
Similarities between UDP-glucose and adenine nucleotide release in yeast: involvement of the secretory pathway.
Esther CR Jr, Sesma JI, Dohlman HG, Ault AD, Clas ML, Lazarowski ER, Boucher RC. Esther CR Jr, et al. Biochemistry. 2008 Sep 2;47(35):9269-78. doi: 10.1021/bi800855k. Epub 2008 Aug 12. Biochemistry. 2008. PMID: 18693752 Free PMC article.
Indeed, total adenine nucleotide release, like UDP-glucose release, did not vary with glucose concentration over the short term. The genetic basis of UDP-glucose release was explored through analysis of deletion mutants, aided by development of a novel bioassay for UDP-glu …
Indeed, total adenine nucleotide release, like UDP-glucose release, did not vary with glucose concentration over the short term. The …