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Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials.
Al-Shahi Salman R, Stephen J, Tierney JF, Lewis SC, Newby DE, Parry-Jones AR, White PM, Connolly SJ, Benavente OR, Dowlatshahi D, Cordonnier C, Viscoli CM, Sheth KN, Kamel H, Veltkamp R, Larsen KT, Hofmeijer J, Kerkhoff H, Schreuder FHBM, Shoamanesh A, Klijn CJM, van der Worp HB; Collaboration of Controlled Randomised Trials of Long-Term Oral Antithrombotic Agents After Spontaneous Intracranial Haemorrhage (COCROACH). Al-Shahi Salman R, et al. Lancet Neurol. 2023 Dec;22(12):1140-1149. doi: 10.1016/S1474-4422(23)00315-0. Epub 2023 Oct 12. Lancet Neurol. 2023. PMID: 37839434 Free article.
We included clinical trials if they were registered, randomised, and included participants with spontaneous intracranial haemorrhage and atrial fibrillation who were assigned to either start long-term use of any oral anticoagulant agent or avoid oral anticoagulation (ie, p …
We included clinical trials if they were registered, randomised, and included participants with spontaneous intracranial haemorrhage and atr …
Contribution of Methanesulfonic Acid to the Formation of Molecular Clusters in the Marine Atmosphere.
Rasmussen FR, Kubečka J, Elm J. Rasmussen FR, et al. Among authors: elm j. J Phys Chem A. 2022 Oct 13;126(40):7127-7136. doi: 10.1021/acs.jpca.2c04468. Epub 2022 Oct 3. J Phys Chem A. 2022. PMID: 36191242
Because of the lack of long-term measurements, new particle formation (NPF) in the marine atmosphere remains puzzling. ...
Because of the lack of long-term measurements, new particle formation (NPF) in the marine atmosphere remains puzzling. ...
Cilostazol for Secondary Stroke Prevention: History, Evidence, Limitations, and Possibilities.
de Havenon A, Sheth KN, Madsen TE, Johnston KC, Turan TN, Toyoda K, Elm JJ, Wardlaw JM, Johnston SC, Williams OA, Shoamanesh A, Lansberg MG. de Havenon A, et al. Among authors: elm jj. Stroke. 2021 Oct;52(10):e635-e645. doi: 10.1161/STROKEAHA.121.035002. Epub 2021 Sep 14. Stroke. 2021. PMID: 34517768 Free PMC article. Review.
If positive, it would increase the evidence in support of long-term treatment with cilostazol for secondary prevention in the millions of patients worldwide who have experienced a noncardioembolic ischemic stroke....
If positive, it would increase the evidence in support of long-term treatment with cilostazol for secondary prevention in the million …
Recombinant factor VIIa for hemorrhagic stroke treatment at earliest possible time (FASTEST): Protocol for a phase III, double-blind, randomized, placebo-controlled trial.
Naidech AM, Grotta J, Elm J, Janis S, Dowlatshahi D, Toyoda K, Steiner T, Mayer SA, Khanolkar P, Denlinger J, Audebert HJ, Molina C, Khatri P, Sprigg N, Vagal A, Broderick JP. Naidech AM, et al. Among authors: elm j. Int J Stroke. 2022 Aug;17(7):806-809. doi: 10.1177/17474930211042700. Epub 2021 Sep 5. Int J Stroke. 2022. PMID: 34427473 Free PMC article.
Hematoma expansion, growth of the hematoma between the baseline computed tomography scan and a follow-up computed tomography scan at 24 6 h, predicts long-term disability or death. Recombinant factor VIIa (rFVIIa) has reduced hematoma expansion in previous clinical trials …
Hematoma expansion, growth of the hematoma between the baseline computed tomography scan and a follow-up computed tomography scan at 24 6 h, …
Clusteromics I: Principles, Protocols, and Applications to Sulfuric Acid-Base Cluster Formation.
Elm J. Elm J. ACS Omega. 2021 Mar 12;6(11):7804-7814. doi: 10.1021/acsomega.1c00306. eCollection 2021 Mar 23. ACS Omega. 2021. PMID: 33778292 Free PMC article.
We recently coined the term clusteromics as a holistic approach for obtaining insight into the chemical complexity of atmospheric molecular cluster formation and at the same time providing the foundation for thermochemical databases that can be utilized for developing mach …
We recently coined the term clusteromics as a holistic approach for obtaining insight into the chemical complexity of atmospheric mol …
BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's Disease.
Fischer DL, Auinger P, Goudreau JL, Cole-Strauss A, Kieburtz K, Elm JJ, Hacker ML, Charles PD, Lipton JW, Pickut BA, Sortwell CE. Fischer DL, et al. Among authors: elm jj. Neurotherapeutics. 2020 Oct;17(4):1785-1795. doi: 10.1007/s13311-020-00965-9. Epub 2020 Nov 19. Neurotherapeutics. 2020. PMID: 33215284 Free PMC article. Clinical Trial.
This study investigated if the BDNF rs6265 single nucleotide polymorphism (SNP) is associated with differential outcomes with specific pharmacotherapy treatment strategies in the "NIH Exploratory Trials in PD Long-term Study 1" (NET-PD LS-1, n = 540). DNA samples were geno …
This study investigated if the BDNF rs6265 single nucleotide polymorphism (SNP) is associated with differential outcomes with specific pharm …
Feasibility and utility of a clinician dashboard from wearable and mobile application Parkinson's disease data.
Elm JJ, Daeschler M, Bataille L, Schneider R, Amara A, Espay AJ, Afek M, Admati C, Teklehaimanot A, Simuni T. Elm JJ, et al. NPJ Digit Med. 2019 Sep 25;2:95. doi: 10.1038/s41746-019-0169-y. eCollection 2019. NPJ Digit Med. 2019. PMID: 31583283 Free PMC article.
Movement, symptoms, and medication intake data were feasibly translated from the app into a clinician dashboard but there was substantial attrition rate over 6 months. Further enhancements are needed to ensure long-term patient adherence to portable technologies and optima …
Movement, symptoms, and medication intake data were feasibly translated from the app into a clinician dashboard but there was substantial at …
Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone After Transient Ischemic Attack or Minor Ischemic Stroke: A Secondary Analysis of the POINT Randomized Clinical Trial.
Tillman H, Johnston SC, Farrant M, Barsan W, Elm JJ, Kim AS, Lindblad AS, Palesch YY, Easton JD. Tillman H, et al. Among authors: elm jj. JAMA Neurol. 2019 Jul 1;76(7):774-782. doi: 10.1001/jamaneurol.2019.0932. JAMA Neurol. 2019. PMID: 31034032 Free PMC article. Clinical Trial.
IMPORTANCE: Results show the short-term risk of hemorrhage in treating patients with acute transient ischemic attack (TIA) or minor acute ischemic stroke (AIS) with clopidogrel plus aspirin or aspirin alone. ...
IMPORTANCE: Results show the short-term risk of hemorrhage in treating patients with acute transient ischemic attack (TIA) or minor a …
Transcranial Direct Current Stimulation vs Sham Stimulation to Treat Aphasia After Stroke: A Randomized Clinical Trial.
Fridriksson J, Rorden C, Elm J, Sen S, George MS, Bonilha L. Fridriksson J, et al. Among authors: elm j. JAMA Neurol. 2018 Dec 1;75(12):1470-1476. doi: 10.1001/jamaneurol.2018.2287. JAMA Neurol. 2018. PMID: 30128538 Free PMC article. Clinical Trial.
OBJECTIVE: To examine the futility of studying A-tDCS as an adjunctive intervention during speech therapy to improve speech production (naming) for individuals with long-term poststroke aphasia. DESIGN, SETTING, AND PARTICIPANTS: Double-blinded, prospective randomized clin …
OBJECTIVE: To examine the futility of studying A-tDCS as an adjunctive intervention during speech therapy to improve speech production (nami …
Long-Term Outcomes in Patients Aged 70 Years With Intravenous Glyburide From the Phase II GAMES-RP Study of Large Hemispheric Infarction: An Exploratory Analysis.
Sheth KN, Petersen NH, Cheung K, Elm JJ, Hinson HE, Molyneaux BJ, Beslow LA, Sze GK, Simard JM, Kimberly WT. Sheth KN, et al. Among authors: elm jj. Stroke. 2018 Jun;49(6):1457-1463. doi: 10.1161/STROKEAHA.117.020365. Epub 2018 May 22. Stroke. 2018. PMID: 29789393 Free PMC article. Clinical Trial.
BACKGROUND AND PURPOSE: We aimed to determine whether subjects aged 70 years who were treated with intravenous glyburide (RP-1127; BIIB093; glibenclamide) would have better long-term outcomes than those who received placebo. METHODS: GAMES-RP (Glyburide Advantage in Malign …
BACKGROUND AND PURPOSE: We aimed to determine whether subjects aged 70 years who were treated with intravenous glyburide (RP-1127; BIIB093; …
24 results