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Efficacy and Safety of the Travoprost Intraocular Implant in Reducing Topical IOP-Lowering Medication Burden in Patients with Open-Angle Glaucoma or Ocular Hypertension.
Berdahl JP, Sarkisian SR Jr, Ang RE, Doan LV, Kothe AC, Usner DW, Katz LJ, Navratil T; Travoprost Intraocular Implant Study Group. Berdahl JP, et al. Drugs. 2024 Jan;84(1):83-97. doi: 10.1007/s40265-023-01973-7. Epub 2023 Dec 7. Drugs. 2024. PMID: 38060092 Free PMC article. Clinical Trial.
PURPOSE: A randomized, double-masked, multicenter, phase 2 trial to evaluate the long-term safety and efficacy of travoprost intraocular implant, an extended-release drug delivery system designed to provide uninterrupted sustained intraocular pressure (IOP)-lowering therap …
PURPOSE: A randomized, double-masked, multicenter, phase 2 trial to evaluate the long-term safety and efficacy of travoprost intraocu …
ATS Core Curriculum 2022. Pediatric Pulmonary Medicine: Updates in pediatric neuromuscular disease.
Leon-Astudillo C, Okorie CUA, McCown MY, Dy FJ, Puranik S, Prero M, ElMallah MK, Treat L, Gross JE. Leon-Astudillo C, et al. Among authors: elmallah mk. Pediatr Pulmonol. 2023 Jul;58(7):1866-1874. doi: 10.1002/ppul.26448. Epub 2023 May 5. Pediatr Pulmonol. 2023. PMID: 37144867 Review.
Despite extraordinary progress in the medical management of NMD, little is known regarding the respiratory implications and long-term outcomes for patients in the era of advanced therapeutics and precision medicine. ...
Despite extraordinary progress in the medical management of NMD, little is known regarding the respiratory implications and long-term …
Higher dosing of alglucosidase alfa improves outcomes in children with Pompe disease: a clinical study and review of the literature.
Khan AA, Case LE, Herbert M, DeArmey S, Jones H, Crisp K, Zimmerman K, ElMallah MK, Young SP, Kishnani PS. Khan AA, et al. Among authors: elmallah mk. Genet Med. 2020 May;22(5):898-907. doi: 10.1038/s41436-019-0738-0. Epub 2020 Jan 6. Genet Med. 2020. PMID: 31904026 Free PMC article. Review.
PURPOSE: Enzyme replacement therapy (ERT) with recombinant human acid-alpha glucosidase (rhGAA) at standard dose of 20 mg/kg every other week is insufficient to halt the long-term progression of myopathy in Pompe disease. METHODS: We conducted a retrospective study on infa …
PURPOSE: Enzyme replacement therapy (ERT) with recombinant human acid-alpha glucosidase (rhGAA) at standard dose of 20 mg/kg every other wee …
Ampakine CX717 potentiates intermittent hypoxia-induced hypoglossal long-term facilitation.
Turner SM, ElMallah MK, Hoyt AK, Greer JJ, Fuller DD. Turner SM, et al. Among authors: elmallah mk. J Neurophysiol. 2016 Sep 1;116(3):1232-8. doi: 10.1152/jn.00210.2016. Epub 2016 Jun 15. J Neurophysiol. 2016. PMID: 27306673 Free PMC article.
Here, we examined if ampakines alter the expression of respiratory long-term facilitation (LTF), a form of neuroplasticity manifested as a persistent increase in inspiratory activity following brief periods of reduced O2 [intermittent hypoxia (IH)]. ...
Here, we examined if ampakines alter the expression of respiratory long-term facilitation (LTF), a form of neuroplasticity manifested …
Power spectral analysis of hypoglossal nerve activity during intermittent hypoxia-induced long-term facilitation in mice.
ElMallah MK, Stanley DA, Lee KZ, Turner SM, Streeter KA, Baekey DM, Fuller DD. ElMallah MK, et al. J Neurophysiol. 2016 Mar;115(3):1372-80. doi: 10.1152/jn.00479.2015. Epub 2015 Dec 16. J Neurophysiol. 2016. PMID: 26683067 Free PMC article.
Acute exposure to intermittent hypoxia can induce a form of neuroplasticity known as long-term facilitation (LTF), in which inspiratory burst amplitude is persistently elevated. ...
Acute exposure to intermittent hypoxia can induce a form of neuroplasticity known as long-term facilitation (LTF), in which inspirato …
Hereditary mucoepithelial dysplasia and severe respiratory distress.
Halawa M, Abu-Hasan MN, ElMallah MK. Halawa M, et al. Among authors: elmallah mk. Respir Med Case Rep. 2015 Apr 8;15:27-9. doi: 10.1016/j.rmcr.2015.03.004. eCollection 2015. Respir Med Case Rep. 2015. PMID: 26236594 Free PMC article.
We present a case of severe respiratory distress in an initially healthy full term infant born to a mother with HMD. This infant later developed signs and symptoms of HMD. ...
We present a case of severe respiratory distress in an initially healthy full term infant born to a mother with HMD. This infant late …