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Development and validation of the risk engine for an Australian Health Economics Model of Osteoporosis.
Si L, Eisman JA, Winzenberg T, Sanders KM, Center JR, Nguyen TV, Tran T, Palmer AJ. Si L, et al. Among authors: eisman ja. Osteoporos Int. 2021 Oct;32(10):2073-2081. doi: 10.1007/s00198-021-05955-x. Epub 2021 Apr 15. Osteoporos Int. 2021. PMID: 33856500
CONCLUSIONS: In summary, the development of the risk engine of AusHEMO followed the best practice for osteoporosis disease modelling and the model has been shown to have good face, internal and cross validities. The AusHEMO can be confidently used to predict long-term frac …
CONCLUSIONS: In summary, the development of the risk engine of AusHEMO followed the best practice for osteoporosis disease modelling and the …
SEVERE HYPERTRIGLYCERIDEMIA ASSOCIATED WITH EVEROLIMUS TREATMENT AFTER HEART TRANSPLANTATION.
Lo P, Kearney K, Muir CA, Song N, Eisman JA, Macdonald PS. Lo P, et al. Among authors: eisman ja. AACE Clin Case Rep. 2020 Sep 21;6(5):e269-e272. doi: 10.4158/ACCR-2020-0191. eCollection 2020 Sep-Oct. AACE Clin Case Rep. 2020. PMID: 32984536 Free PMC article.
However, it can confer adverse effects such as dyslipidemia, which is not underpinned by any long-term screening and management of dyslipidemia in heart transplant recipients treated with everolimus. ...
However, it can confer adverse effects such as dyslipidemia, which is not underpinned by any long-term screening and management of dy …
Roux-en-Y gastric bypass and gastric sleeve surgery result in long term bone loss.
Brzozowska MM, Tran T, Bliuc D, Jorgensen J, Talbot M, Fenton-Lee D, Chen W, Hong A, Viardot A, White CP, Nguyen TV, Pocock N, Eisman JA, Baldock PA, Center JR. Brzozowska MM, et al. Among authors: eisman ja. Int J Obes (Lond). 2021 Jan;45(1):235-246. doi: 10.1038/s41366-020-00660-x. Epub 2020 Aug 26. Int J Obes (Lond). 2021. PMID: 32848203
OBJECTIVES: Little is known about the long-term skeletal impact of bariatric procedures, particularly the increasingly commonly performed gastric sleeve surgery (GS). ...
OBJECTIVES: Little is known about the long-term skeletal impact of bariatric procedures, particularly the increasingly commonly perfo …
Association between vertebral fractures and coronary artery calcification in current and former smokers in the ECLIPSE cohort.
van Dort MJ, Driessen JHM, Geusens P, Romme EAPM, Smeenk FWJM, Rahel BM, Eisman JA, Wouters EFM, van den Bergh JPW. van Dort MJ, et al. Among authors: eisman ja. Osteoporos Int. 2020 Feb;31(2):297-305. doi: 10.1007/s00198-019-05218-w. Epub 2019 Nov 25. Osteoporos Int. 2020. PMID: 31768590 Free PMC article.
Similarly, after adjustment for BA, high (OR = 2.06 [1.02-4.13]) but not medium Agatston score (OR = 1.61 [0.88-2.94]) was associated with prevalent VFs. Agatston score at baseline was not associated with short-term VF incidence. CONCLUSION: In (former) smokers, there was …
Similarly, after adjustment for BA, high (OR = 2.06 [1.02-4.13]) but not medium Agatston score (OR = 1.61 [0.88-2.94]) was associated with p …
Persistence of Excess Mortality Following Individual Nonhip Fractures: A Relative Survival Analysis.
Tran T, Bliuc D, Hansen L, Abrahamsen B, van den Bergh J, Eisman JA, van Geel T, Geusens P, Vestergaard P, Nguyen TV, Center JR. Tran T, et al. Among authors: eisman ja. J Clin Endocrinol Metab. 2018 Sep 1;103(9):3205-3214. doi: 10.1210/jc.2017-02656. J Clin Endocrinol Metab. 2018. PMID: 30053007
CONTEXT: Little is known about long-term excess mortality following fragility nonhip fractures. OBJECTIVE: The study aimed to determine which fracture was associated with excess mortality and for how long the postfracture excess mortality persisted. ...CONCLUSION: This stu …
CONTEXT: Little is known about long-term excess mortality following fragility nonhip fractures. OBJECTIVE: The study aimed to determi …
Prediction of changes in bone mineral density in the elderly: contribution of "osteogenomic profile".
Ho-Le TP, Pham HM, Center JR, Eisman JA, Nguyen HT, Nguyen TV. Ho-Le TP, et al. Among authors: eisman ja. Arch Osteoporos. 2018 Jun 21;13(1):68. doi: 10.1007/s11657-018-0480-2. Arch Osteoporos. 2018. PMID: 29931598
CONCLUSIONS: We conclude that the osteogenomic profile constructed from BMD-associated genetic variants is modestly associated with long-term changes in femoral neck BMD in women, but not in men....
CONCLUSIONS: We conclude that the osteogenomic profile constructed from BMD-associated genetic variants is modestly associated with long- …
Fracture Risk Assessment: From Population to Individual.
Nguyen TV, Eisman JA. Nguyen TV, et al. Among authors: eisman ja. J Clin Densitom. 2017 Jul-Sep;20(3):368-378. doi: 10.1016/j.jocd.2017.06.023. Epub 2017 Jul 17. J Clin Densitom. 2017. PMID: 28729045
Although the prognostic performance of Garvan and FRAX() for fracture prediction is not perfect and there is room for further improvement, these predictive models can aid patients and doctors communicate about fracture risk in the medium term and to make rational decisions …
Although the prognostic performance of Garvan and FRAX() for fracture prediction is not perfect and there is room for further improvement, t …
Population-Wide Impact of Non-Hip Non-Vertebral Fractures on Mortality.
Tran T, Bliuc D, van Geel T, Adachi JD, Berger C, van den Bergh J, Eisman JA, Geusens P, Goltzman D, Hanley DA, Josse RG, Kaiser SM, Kovacs CS, Langsetmo L, Prior JC, Nguyen TV, Center JR. Tran T, et al. Among authors: eisman ja. J Bone Miner Res. 2017 Sep;32(9):1802-1810. doi: 10.1002/jbmr.3118. Epub 2017 May 15. J Bone Miner Res. 2017. PMID: 28256011 Free article. Clinical Trial.
Data on long-term consequences of non-hip non-vertebral (NHNV) fractures, accounting for approximately two-thirds of all fragility fractures, are scanty. ...
Data on long-term consequences of non-hip non-vertebral (NHNV) fractures, accounting for approximately two-thirds of all fragility fr …
Erratum to: Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the Long-Term Odanacatib Fracture Trial.
Bone HG, Dempster DW, Eisman JA, Greenspan SL, McClung MR, Nakamura T, Papapoulos S, Shih WJ, Rybak-Feiglin A, Santora AC, Verbruggen N, Leung AT, Lombardi A. Bone HG, et al. Among authors: eisman ja. Osteoporos Int. 2015 Nov;26(11):2721. doi: 10.1007/s00198-015-3274-z. Osteoporos Int. 2015. PMID: 26359183 Free PMC article. No abstract available.
Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the Long-Term Odanacatib Fracture Trial.
Bone HG, Dempster DW, Eisman JA, Greenspan SL, McClung MR, Nakamura T, Papapoulos S, Shih WJ, Rybak-Feiglin A, Santora AC, Verbruggen N, Leung AT, Lombardi A. Bone HG, et al. Among authors: eisman ja. Osteoporos Int. 2015 Feb;26(2):699-712. doi: 10.1007/s00198-014-2944-6. Epub 2014 Nov 29. Osteoporos Int. 2015. PMID: 25432773 Free PMC article. Clinical Trial.
In a phase 2 trial, ODN 50 mg once weekly reduced bone resorption while preserving bone formation and progressively increased BMD over 5 years. We describe the phase III Long-Term ODN Fracture Trial (LOFT), an event-driven, randomized, blinded placebo-controlled trial, wit …
In a phase 2 trial, ODN 50 mg once weekly reduced bone resorption while preserving bone formation and progressively increased BMD over 5 yea …
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