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Friend virus-infected long-term bone marrow cultures produce colony stimulating factor dependent and independent granulocyte-macrophage progenitor cells for over four years in vitro.
Greenberger JS, Daugherty C, Sakakeeny MA, Braun J, Pierce JH, Eckner RJ, FitzGerald TJ. Greenberger JS, et al. Among authors: eckner rj. Leuk Res. 1987;11(1):51-61. doi: 10.1016/0145-2126(87)90105-6. Leuk Res. 1987. PMID: 3492638
Despite generation of clonal malignant cell lines, L-cell DSF (CSF-1, M-CSF) responsive GM-CFUc that were simultaneously produced over 4 years in the same long-term marrow cultures, grew to 7 day colonies in semisolid medium and terminally differentiated. Thus, adherent st …
Despite generation of clonal malignant cell lines, L-cell DSF (CSF-1, M-CSF) responsive GM-CFUc that were simultaneously produced over 4 yea …
Role of stromal and hematopoietic stem cells in Friend spleen focus forming virus effects in continuous bone marrow culture.
Greenberger JS, Eckner RJ, Sakakeeny MA, Cohen GI. Greenberger JS, et al. Among authors: eckner rj. Leuk Res. 1983;7(5):621-36. doi: 10.1016/0145-2126(83)90133-9. Leuk Res. 1983. PMID: 6645600
Thus, these data indicate that the prolongation of hematopoiesis in undisturbed long-term marrow cultures by SFFV occurs through an interaction of adherent hematopoietic stem cells with the marrow stroma....
Thus, these data indicate that the prolongation of hematopoiesis in undisturbed long-term marrow cultures by SFFV occurs through an i …