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In Situ Investigation of Pseudomonas aeruginosa Biofilm Development: Interplay between Flow, Growth Medium, and Mechanical Properties of Substrate.
Straub H, Zuber F, Eberl L, Maniura-Weber K, Ren Q. Straub H, et al. Among authors: eberl l. ACS Appl Mater Interfaces. 2023 Jan 18;15(2):2781-2791. doi: 10.1021/acsami.2c20693. Epub 2023 Jan 5. ACS Appl Mater Interfaces. 2023. PMID: 36601891
Interestingly, magnesium rather than previously reported calcium was identified here to play a decisive role in the formation of dense P. aeruginosa aggregates and high levels of c-di-GMP. These results demonstrate that although short-term adhesion assays bring valuable in …
Interestingly, magnesium rather than previously reported calcium was identified here to play a decisive role in the formation of dense P. ae …
Deciphering the Enigmatic Function of Pseudomonas Metallothioneins.
Habjanič J, Mathew A, Eberl L, Freisinger E. Habjanič J, et al. Among authors: eberl l. Front Microbiol. 2020 Jul 22;11:1709. doi: 10.3389/fmicb.2020.01709. eCollection 2020. Front Microbiol. 2020. PMID: 32793167 Free PMC article.
We show that MT expression is only induced in the stationary phase and provides a fitness benefit for long-term starvation survival, while it is not required for metal resistance and acquisition, oxidative or nitrosative stress response, biofilm formation or motility....
We show that MT expression is only induced in the stationary phase and provides a fitness benefit for long-term starvation survival, …
Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms.
Cárcamo-Oyarce G, Lumjiaktase P, Kümmerli R, Eberl L. Cárcamo-Oyarce G, et al. Among authors: eberl l. Nat Commun. 2015 Jan 16;6:5945. doi: 10.1038/ncomms6945. Nat Commun. 2015. PMID: 25592773 Free PMC article.
The term 'quorum sensing' (QS) is generally used to describe the phenomenon that bacteria release and perceive signal molecules to coordinate cooperative behaviour in response to their population size. ...
The term 'quorum sensing' (QS) is generally used to describe the phenomenon that bacteria release and perceive signal molecules to co …
Cystic fibrosis-niche adaptation of Pseudomonas aeruginosa reduces virulence in multiple infection hosts.
Lorè NI, Cigana C, De Fino I, Riva C, Juhas M, Schwager S, Eberl L, Bragonzi A. Lorè NI, et al. Among authors: eberl l. PLoS One. 2012;7(4):e35648. doi: 10.1371/journal.pone.0035648. Epub 2012 Apr 25. PLoS One. 2012. PMID: 22558188 Free PMC article.
P. aeruginosa environmental strains are producing various virulence factors that are required for establishing acute infections in several host organisms; however, the P. aeruginosa phenotypic variants favour long-term persistence in the cystic fibrosis (CF) airways. Wheth …
P. aeruginosa environmental strains are producing various virulence factors that are required for establishing acute infections in several h …
Virulence of Burkholderia cepacia complex strains in gp91phox-/- mice.
Sousa SA, Ulrich M, Bragonzi A, Burke M, Worlitzsch D, Leitão JH, Meisner C, Eberl L, Sá-Correia I, Döring G. Sousa SA, et al. Among authors: eberl l. Cell Microbiol. 2007 Dec;9(12):2817-25. doi: 10.1111/j.1462-5822.2007.00998.x. Epub 2007 Jul 11. Cell Microbiol. 2007. PMID: 17627623
In cystic fibrosis (CF), infection with Burkholderia cepacia complex (Bcc) strains may cause long-term asymptomatic airway colonization, or severe lung infection leading to rapid pulmonary decline. ...
In cystic fibrosis (CF), infection with Burkholderia cepacia complex (Bcc) strains may cause long-term asymptomatic airway colonizati …
Influence of polyphenols on bacterial biofilm formation and quorum-sensing.
Huber B, Eberl L, Feucht W, Polster J. Huber B, et al. Among authors: eberl l. Z Naturforsch C J Biosci. 2003 Nov-Dec;58(11-12):879-84. doi: 10.1515/znc-2003-11-1224. Z Naturforsch C J Biosci. 2003. PMID: 14713169 Free article.
Many bacteria utilize sophisticated regulatory systems to ensure that some functions are only expressed when a particular population density has been reached. The term 'quorum-sensing' has been coined to describe this form of density-dependent gene regulation which relies …
Many bacteria utilize sophisticated regulatory systems to ensure that some functions are only expressed when a particular population density …
The endothelin system in human glioblastoma.
Egidy G, Eberl LP, Valdenaire O, Irmler M, Majdi R, Diserens AC, Fontana A, Janzer RC, Pinet F, Juillerat-Jeanneret L. Egidy G, et al. Among authors: eberl lp. Lab Invest. 2000 Nov;80(11):1681-9. doi: 10.1038/labinvest.3780178. Lab Invest. 2000. PMID: 11092528 Free article.
ET-1 induced transient phosphorylation of extracellular signal-regulated kinase but did not induce long-term thymidine incorporation in LNZ308 glioblastoma cells. These results suggest that, in glioblastoma cells, ET-1, mainly acting via the ET(B) receptor, is a survival/a …
ET-1 induced transient phosphorylation of extracellular signal-regulated kinase but did not induce long-term thymidine incorporation …
Physiological responses of Pseudomonas putida KT2442 to phosphate starvation.
Eberl L, Givskov M, Sternberg C, Møller S, Christiansen G, Molin S. Eberl L, et al. Microbiology (Reading). 1996 Jan;142(1):155-163. doi: 10.1099/13500872-142-1-155. Microbiology (Reading). 1996. PMID: 33657738 Free article.
By employing a bioluminescence-based marker system, we demonstrated that this mutant is able to replace wild-type cells in mixed culture experiments. Thus, long-term phosphate-deprived cultures represent dynamic regimes that can undergo population shifts....
By employing a bioluminescence-based marker system, we demonstrated that this mutant is able to replace wild-type cells in mixed culture exp …