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Randomized controlled study of aerosolized hypertonic xylitol versus hypertonic saline in hospitalized patients with pulmonary exacerbation of cystic fibrosis.
Singh S, Hornick D, Fedler J, Launspach JL, Teresi ME, Santacroce TR, Cavanaugh JE, Horan R, Nelson G, Starner TD, Zabner J, Durairaj L. Singh S, et al. Among authors: durairaj l. J Cyst Fibros. 2020 Jan;19(1):108-113. doi: 10.1016/j.jcf.2019.06.016. Epub 2019 Jul 18. J Cyst Fibros. 2020. PMID: 31327670 Free PMC article. Clinical Trial.
CONCLUSIONS: Aerosolized hypertonic xylitol was well-tolerated among subjects hospitalized for CF pulmonary exacerbation. Future studies examining efficacy for long term use in patients with CF lung disease would be worthwhile. The clinical trial registration number for th …
CONCLUSIONS: Aerosolized hypertonic xylitol was well-tolerated among subjects hospitalized for CF pulmonary exacerbation. Future studies exa …
Inhaled hypertonic saline in adults hospitalised for exacerbation of cystic fibrosis lung disease: a retrospective study.
Pezzulo AA, Stoltz DA, Hornick DB, Durairaj L. Pezzulo AA, et al. Among authors: durairaj l. BMJ Open. 2012 Apr 19;2(2):e000407. doi: 10.1136/bmjopen-2011-000407. Print 2012. BMJ Open. 2012. PMID: 22517980 Free PMC article.
BACKGROUND: Inhaled hypertonic saline (HTS) improves quality of life and reduces pulmonary exacerbations when given long term in patients with cystic fibrosis (CF). While increasingly being offered for acute pulmonary exacerbations, little is known about the efficacy in th …
BACKGROUND: Inhaled hypertonic saline (HTS) improves quality of life and reduces pulmonary exacerbations when given long term in pati …
Safety assessment of inhaled xylitol in subjects with cystic fibrosis.
Durairaj L, Launspach J, Watt JL, Mohamad Z, Kline J, Zabner J. Durairaj L, et al. J Cyst Fibros. 2007 Jan;6(1):31-4. doi: 10.1016/j.jcf.2006.05.002. Epub 2006 Jun 15. J Cyst Fibros. 2007. PMID: 16781897 Free article. Clinical Trial.
CONCLUSIONS: A single dose inhalation of aerosolized iso-osmotic xylitol was well tolerated by subjects with cystic fibrosis. Future studies of long term safety are required....
CONCLUSIONS: A single dose inhalation of aerosolized iso-osmotic xylitol was well tolerated by subjects with cystic fibrosis. Future studies …