Short-term metformin ingestion by healthy older adults improves myoblast function.
Mahmassani ZS, McKenzie AI, Petrocelli JJ, de Hart NM, Reidy PT, Fix DK, Ferrara PJ, Funai K, Drummond MJ.
Mahmassani ZS, et al. Among authors: drummond mj.
Am J Physiol Cell Physiol. 2021 Apr 1;320(4):C566-C576. doi: 10.1152/ajpcell.00469.2020. Epub 2021 Jan 6.
Am J Physiol Cell Physiol. 2021.
PMID: 33406027
Free PMC article.
MPCs from Old subjects had lower fusion index and myoblast-endothelial cell homing compared with Young, while Old MPCs, extracted after short-term metformin ingestion, performed better at both tasks. Transcriptomic analyses of Old MPCs (vs. ...
MPCs from Old subjects had lower fusion index and myoblast-endothelial cell homing compared with Young, while Old MPCs, extracted after shor …