Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

20 results

Filters applied: . Clear all
Page 1
Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia.
Wang Q, Qiu H, Jiang H, Wu L, Dong S, Pan J, Wang W, Ping N, Xia J, Sun A, Wu D, Xue Y, Drexler HG, Macleod RA, Chen S. Wang Q, et al. Among authors: drexler hg. Haematologica. 2011 Dec;96(12):1808-14. doi: 10.3324/haematol.2011.043083. Epub 2011 Aug 31. Haematologica. 2011. PMID: 21880637 Free PMC article. Clinical Trial.
No differences in disease-free survival and overall survival between T-cell acute lymphoblastic leukemia patients with and without PHF6 mutations were observed in a short-term follow-up. CONCLUSIONS: Overall, these results indicate that, in T-cell acute lymphoblastic leuke …
No differences in disease-free survival and overall survival between T-cell acute lymphoblastic leukemia patients with and without PHF6 muta …
Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas.
Drexler HG, Gignac SM, von Wasielewski R, Werner M, Dirks WG. Drexler HG, et al. Leukemia. 2000 Sep;14(9):1533-59. doi: 10.1038/sj.leu.2401878. Leukemia. 2000. PMID: 10994999 Review.
The fact that patients with ALK lymphomas experience significantly better overall survival than ALK- ALCL demonstrates further that analysis of ALK expression has important prognostic implications. The term ALK lymphoma signifies a switch in the use of the diagnostic crite …
The fact that patients with ALK lymphomas experience significantly better overall survival than ALK- ALCL demonstrates further that analysis …
Human bone marrow stroma-dependent cell line MOLP-5 derived from a patient in leukaemic phase of multiple myeloma.
Matsuo Y, Drexler HG, Nishizaki C, Harashima A, Fukuda S, Kozuka T, Sezaki T, Orita K. Matsuo Y, et al. Among authors: drexler hg. Br J Haematol. 2000 Apr;109(1):54-63. doi: 10.1046/j.1365-2141.2000.01985.x. Br J Haematol. 2000. PMID: 10848782 Free article.
Interleukin 6 (IL-6) receptor mRNA was found in the reverse transcriptase polymerase chain reaction (RT-PCR) analysis. IL-6 and IL-10 could induce cellular proliferation in short-term induction experiments. IL-6 or IL-10 production was not detected by specific enzyme-linke …
Interleukin 6 (IL-6) receptor mRNA was found in the reverse transcriptase polymerase chain reaction (RT-PCR) analysis. IL-6 and IL-10 could …
Effects of thrombopoietin, interleukin-3 and the kinase inhibitor K-252a on growth and polyploidization of the megakaryocytic cell line M-07e.
Quentmeier H, Zaborski M, Drexler HG. Quentmeier H, et al. Among authors: drexler hg. Leukemia. 1998 Oct;12(10):1603-11. doi: 10.1038/sj.leu.2401170. Leukemia. 1998. PMID: 9766506
Thus, the TPO-receptor (TPO-R) MPL was tyrosine phosphorylated after a short-term stimulation with TPO, followed by tyrosine phosphorylation of STAT 3 and STAT 5, but not of STAT 1. ...The second major effect of TPO, polypoidization, could not be observed in M-07e cells. E …
Thus, the TPO-receptor (TPO-R) MPL was tyrosine phosphorylated after a short-term stimulation with TPO, followed by tyrosine phosphor …
Interferon-gamma induced proliferation of human myeloid leukaemia cell lines.
Drexler HG, Zaborski M, Quentmeier H. Drexler HG, et al. Br J Haematol. 1997 Sep;98(3):699-710. doi: 10.1046/j.1365-2141.1997.2673084.x. Br J Haematol. 1997. PMID: 9332328 Free article.
No proliferative response was seen in autonomously growing cell lines; however, 11/19 constitutively growth factor-dependent cell lines showed a significant response in short-term proliferation assays upon incubation with IFN-gamma. The stimulation indices ranged from 2 to …
No proliferative response was seen in autonomously growing cell lines; however, 11/19 constitutively growth factor-dependent cell lines show …
Cytokine response profiles of human myeloid factor-dependent leukemia cell lines.
Drexler HG, Zaborski M, Quentmeier H. Drexler HG, et al. Leukemia. 1997 May;11(5):701-8. doi: 10.1038/sj.leu.2400633. Leukemia. 1997. PMID: 9180295
A proliferative or anti-proliferative response to these 41 cytokines was assessed by the short-term 3H-thymidine uptake assay. A proliferative response was considered as positive when the stimulation index (SI) was >2; inhibition was regarded as significant with an SI & …
A proliferative or anti-proliferative response to these 41 cytokines was assessed by the short-term 3H-thymidine uptake assay. A prol …
Thrombopoietin supports the continuous growth of cytokine-dependent human leukemia cell lines.
Drexler HG, Zaborski M, Quentmeier H. Drexler HG, et al. Leukemia. 1997 Apr;11(4):541-51. doi: 10.1038/sj.leu.2400621. Leukemia. 1997. PMID: 9096695
The acute myeloid leukemia (AML)-derived cell lines HU-3, M-07e, M-MOK and TF-1 have absolute dependence on granulocyte-macrophage colony-stimulating factor (GM-CSF). We cultured these cells long term (> 6 months) in the continuous presence of TPO (omitting GM-CSF). ... …
The acute myeloid leukemia (AML)-derived cell lines HU-3, M-07e, M-MOK and TF-1 have absolute dependence on granulocyte-macrophage colony-st …
MUTZ-3, a monocytic model cell line for interleukin-4 and lipopolysaccharide studies.
Quentmeier H, Duschl A, Hu ZB, Schnarr B, Zaborski M, Drexler HG. Quentmeier H, et al. Among authors: drexler hg. Immunology. 1996 Dec;89(4):606-12. doi: 10.1046/j.1365-2567.1996.d01-780.x. Immunology. 1996. PMID: 9014829 Free PMC article.
Flow cytometric and immunoprecipitation analysis revealed expression of both IL-4R chains in both cell lines. In addition, short-term stimulation with IL-4 induced tyrosine-phosphorylation of the gamma c chain. As both cell lines also expressed signal transducer and activa …
Flow cytometric and immunoprecipitation analysis revealed expression of both IL-4R chains in both cell lines. In addition, short-term …
Chromosomal breakage correlates with delayed lethality in normal and ataxia telangiectasia cell lines treated with bleomycin.
MacLeod RA, Buchheim T, Kaufmann M, Drexler HG. MacLeod RA, et al. Among authors: drexler hg. Mutat Res. 1996 Nov 11;372(1):33-42. doi: 10.1016/S0027-5107(96)00106-6. Mutat Res. 1996. PMID: 9003529
The following endpoints were studied: (1) the maximum (initial) yields of different classes of chromosomal aberrations (CA) produced in G2-phase; (2) the percentage distributions of cells within bins with different numbers of CA; (3) short-term (0-48 h) viability and proli …
The following endpoints were studied: (1) the maximum (initial) yields of different classes of chromosomal aberrations (CA) produced in G2-p …
Expression of the receptor MPL and proliferative effects of its ligand thrombopoietin on human leukemia cells.
Quentmeier H, Zaborski M, Graf G, Ludwig WD, Drexler HG. Quentmeier H, et al. Among authors: drexler hg. Leukemia. 1996 Feb;10(2):297-310. Leukemia. 1996. PMID: 8637239
This growth factor-dependent cell line which is normally cultured in conditioned medium containing several cytokines could be grown in long-term culture supplemented only with TPO. Co-incubation of M-07e with various cytokines and TPO showed additive proliferative effects …
This growth factor-dependent cell line which is normally cultured in conditioned medium containing several cytokines could be grown in long- …
20 results