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Cystic fibrosis papers of the year 2017.
Doull I. Doull I. Paediatr Respir Rev. 2018 Jun;27:2-5. doi: 10.1016/j.prrv.2018.03.001. Epub 2018 Mar 15. Paediatr Respir Rev. 2018. PMID: 29627168 Review.
The evidence base for small molecule therapies in CF has continued to expand, with evidence for lumacaftor/ivacaftor in younger patients and longer-term evidence in adults, and pivotal studies on tezacaftor/ivacaftor. ...
The evidence base for small molecule therapies in CF has continued to expand, with evidence for lumacaftor/ivacaftor in younger patients and …
Bronchiectasis following treatment for high-risk neuroblastoma: A case series.
Adams M, Traunecker H, Doull I, Cox R. Adams M, et al. Among authors: doull i. Pediatr Blood Cancer. 2017 Oct;64(10). doi: 10.1002/pbc.26509. Epub 2017 Mar 10. Pediatr Blood Cancer. 2017. PMID: 28296062
High-risk (HR) neuroblastoma remains a very challenging disease to treat and long-term cure is only possible with intensive, multimodal treatment including chemotherapy, high-dose therapy, radiotherapy, surgery, and immunotherapy. ...
High-risk (HR) neuroblastoma remains a very challenging disease to treat and long-term cure is only possible with intensive, multimod …
Behavioural, educational and respiratory outcomes of antenatal betamethasone for term caesarean section (ASTECS trial).
Stutchfield PR, Whitaker R, Gliddon AE, Hobson L, Kotecha S, Doull IJ. Stutchfield PR, et al. Among authors: doull ij. Arch Dis Child Fetal Neonatal Ed. 2013 May;98(3):F195-200. doi: 10.1136/archdischild-2012-303157. Epub 2013 Feb 19. Arch Dis Child Fetal Neonatal Ed. 2013. PMID: 23424017 Free PMC article. Clinical Trial.
OBJECTIVES: To determine whether antenatal betamethasone prior to elective term caesarean section (CS) affects long term behavioural, cognitive or developmental outcome, and whether the risk of asthma or atopic disease is reduced. DESIGN: A questionnaire based follo …
OBJECTIVES: To determine whether antenatal betamethasone prior to elective term caesarean section (CS) affects long term behav …
Current therapy for bronchiolitis.
Nagakumar P, Doull I. Nagakumar P, et al. Among authors: doull i. Arch Dis Child. 2012 Sep;97(9):827-30. doi: 10.1136/archdischild-2011-301579. Epub 2012 Jun 25. Arch Dis Child. 2012. PMID: 22734014 Review.
More recently, nebulised epinephrine has been demonstrated to offer short term benefits, while two stratagems have shown promise in decreasing risk of hospitalisation and length of hospital stay. ...
More recently, nebulised epinephrine has been demonstrated to offer short term benefits, while two stratagems have shown promise in d …
Full, shared and hybrid paediatric care for cystic fibrosis in South and Mid Wales.
Doull I, Evans H; South and Mid Wales Paediatric Cystic Fibrosis Network. Doull I, et al. Arch Dis Child. 2012 Jan;97(1):17-20. doi: 10.1136/adc.2010.199380. Epub 2011 Feb 13. Arch Dis Child. 2012. PMID: 21317431
CONCLUSIONS: These differences in pulmonary function are likely to reflect the model of care received, and may affect long term outcomes....
CONCLUSIONS: These differences in pulmonary function are likely to reflect the model of care received, and may affect long term outco …
Management of bronchiolitis.
Adams M, Doull I. Adams M, et al. Among authors: doull i. Paediatr Child Health (Oxford). 2009 Jun;19(6):266-270. doi: 10.1016/j.paed.2009.03.001. Epub 2009 May 13. Paediatr Child Health (Oxford). 2009. PMID: 32288783 Free PMC article. Review.
Agents with evidence of no benefit in acute bronchiolitis include beta(2) agonists, ipratropium, montelukast, corticosteroids, antiviral agents such as ribavirin or RSV immunoglobulin, physiotherapy, nebulized deoxyribonuclease or antibiotics. It is possible that nebulized epinep …
Agents with evidence of no benefit in acute bronchiolitis include beta(2) agonists, ipratropium, montelukast, corticosteroids, antiviral age …
The effect of asthma and its treatment on growth.
Doull IJ. Doull IJ. Arch Dis Child. 2004 Jan;89(1):60-3. doi: 10.1136/adc.2003.014365. Arch Dis Child. 2004. PMID: 14709510 Free PMC article. Review.
Recent longitudinal studies offer reassurance that at conventional doses ICS do not have significant long term effects on growth, and that their benefits consistently outweigh their side effects....
Recent longitudinal studies offer reassurance that at conventional doses ICS do not have significant long term effects on growth, and …