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Page 1
Herpes zoster opthalmicus.
Cockburn DM, Douglas IS. Cockburn DM, et al. Among authors: douglas is. Clin Exp Optom. 2000 Mar-Apr;83(2):59-64. doi: 10.1111/j.1444-0938.2000.tb04893.x. Clin Exp Optom. 2000. PMID: 12472455
Although involvement of the nasociliary branch of the first division of the trigeminal nerve is well recognised to be associated with serious and direct ocular morbidity, the need for careful long-term follow-up of cases of frontal branch involvement is perhaps less well k …
Although involvement of the nasociliary branch of the first division of the trigeminal nerve is well recognised to be associated with seriou …
Association of Proximity to a Long-Term Acute Care Hospital With Hospital Tracheostomy Practices.
Mehta AB, Matlock D, Douglas IS. Mehta AB, et al. Among authors: douglas is. Crit Care Med. 2022 Jan 1;50(1):93-102. doi: 10.1097/CCM.0000000000005146. Crit Care Med. 2022. PMID: 34166292 Free PMC article.
It is unclear if long-term acute care hospital availability can influence patient care decisions. ...Patients had a 32.4% (95% CI, 27.6-37.3%) higher risk of tracheostomy when admitted to a hospital with more long-term acute care hospital beds in the immediate vicin …
It is unclear if long-term acute care hospital availability can influence patient care decisions. ...Patients had a 32.4% (95% CI, 27 …
One-Year Outcomes Following Tracheostomy for Acute Respiratory Failure.
Mehta AB, Walkey AJ, Curran-Everett D, Douglas IS. Mehta AB, et al. Among authors: douglas is. Crit Care Med. 2019 Nov;47(11):1572-1581. doi: 10.1097/CCM.0000000000003959. Crit Care Med. 2019. PMID: 31397716 Free PMC article.
CONCLUSIONS: Long-term outcomes following tracheostomy are extremely poor with high mortality, morbidity, and healthcare resource utilization especially among older patients. ...If extended to the entire U.S. population, total short-term acute care hospital costs ap …
CONCLUSIONS: Long-term outcomes following tracheostomy are extremely poor with high mortality, morbidity, and healthcare resource uti …
Drivers of Decision-Making for Adult Tracheostomy for Prolonged Mechanical Ventilation: A Qualitative Study.
Mehta AB, Lockhart S, Lange AV, Matlock DD, Douglas IS, Morris MA. Mehta AB, et al. Among authors: douglas is. medRxiv [Preprint]. 2024 Jan 21:2024.01.20.24301492. doi: 10.1101/2024.01.20.24301492. medRxiv. 2024. PMID: 38293156 Free PMC article. Preprint.
Patient Wishes, Past Activity/Medical History, Short and Long-Term Outcomes, and Meaningful Recovery were key factors upon which surrogates and physicians based decision-making. ...HIGHLIGHTS: Decision-making for tracheostomy and prolonged mechanical ventilation is a compl …
Patient Wishes, Past Activity/Medical History, Short and Long-Term Outcomes, and Meaningful Recovery were key factors upon which surr …
Core Outcomes Set for Trials in People With Coronavirus Disease 2019.
Tong A, Elliott JH, Azevedo LC, Baumgart A, Bersten A, Cervantes L, Chew DP, Cho Y, Cooper T, Crowe S, Douglas IS, Evangelidis N, Flemyng E, Hannan E, Horby P, Howell M, Lee J, Liu E, Lorca E, Lynch D, Marshall JC, Gonzalez AM, McKenzie A, Manera KE, McLeod C, Mehta S, Mer M, Morris AC, Nseir S, Povoa P, Reid M, Sakr Y, Shen N, Smyth AR, Snelling T, Strippoli GF, Teixeira-Pinto A, Torres A, Turner T, Viecelli AK, Webb S, Williamson PR, Woc-Colburn L, Zhang J, Craig JC; COVID-19-Core Outcomes Set (COS) Workshop Investigators. Tong A, et al. Among authors: douglas is. Crit Care Med. 2020 Nov;48(11):1622-1635. doi: 10.1097/CCM.0000000000004585. Crit Care Med. 2020. PMID: 32804792 Free PMC article.
"Encompassing the full trajectory and severity of disease" was addressing longer term impacts and the full spectrum of illness (e.g. shortness of breath and recovery). ...
"Encompassing the full trajectory and severity of disease" was addressing longer term impacts and the full spectrum of illness (e.g. …
Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA).
Rosas IO, Bräu N, Waters M, Go RC, Malhotra A, Hunter BD, Bhagani S, Skiest D, Savic S, Douglas IS, Garcia-Diaz J, Aziz MS, Cooper N, Youngstein T, Sorbo LD, Zerda DJ, Ustianowski A, Gracian AC, Blyth KG, Carratalà J, François B, Benfield T, Haslem D, Bonfanti P, van der Leest CH, Rohatgi N, Wiese L, Luyt CE, Bauer RN, Cai F, Lee IT, Matharu B, Metcalf L, Wildum S, Graham E, Tsai L, Bao M. Rosas IO, et al. Among authors: douglas is. EClinicalMedicine. 2022 May;47:101409. doi: 10.1016/j.eclinm.2022.101409. Epub 2022 Apr 21. EClinicalMedicine. 2022. PMID: 35475258 Free PMC article.
BACKGROUND: In COVACTA, a randomised, placebo-controlled trial in patients hospitalised with coronavirus disease-19 (COVID-19), tocilizumab did not improve 28-day mortality, but shortened hospital and intensive care unit stay. Longer-term effects of tocilizumab in patients …
BACKGROUND: In COVACTA, a randomised, placebo-controlled trial in patients hospitalised with coronavirus disease-19 (COVID-19), tocilizumab …
Perspectives of patients, family members, health professionals and the public on the impact of COVID-19 on mental health.
Gardiner E, Baumgart A, Tong A, Elliott JH, Azevedo LC, Bersten A, Cervantes L, Chew DP, Cho Y, Crowe S, Douglas IS, Evangelidis N, Flemyng E, Horby P, Howell M, Lee J, Lorca E, Lynch D, Marshall JC, Gonzalez AM, McKenzie A, Manera K, Mehta S, Mer M, Morris AC, Nseir S, Povoa P, Reid M, Sakr Y, Shen N, Smyth AR, Snelling T, Strippoli GFM, Teixeira-Pinto A, Torres A, Viecelli AK, Webb S, Williamson PR, Woc-Colburn L, Zhang J, Craig JC. Gardiner E, et al. Among authors: douglas is. J Ment Health. 2022 Aug;31(4):524-533. doi: 10.1080/09638237.2021.2022637. Epub 2022 Jan 4. J Ment Health. 2022. PMID: 34983279
CONCLUSION: We found that the unpredictability of COVID-19, the fear of long-term health consequences, burden of guilt, and suffering in isolation profoundly impacted mental health. ...
CONCLUSION: We found that the unpredictability of COVID-19, the fear of long-term health consequences, burden of guilt, and suffering …
Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.
Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, Ventetuolo CE, Vieillard-Baron A, Voelkel NF, Vonk-Noordegraaf A, Hassoun PM; American Thoracic Society Assembly on Pulmonary Circulation. Lahm T, et al. Among authors: douglas is. Am J Respir Crit Care Med. 2018 Aug 15;198(4):e15-e43. doi: 10.1164/rccm.201806-1160ST. Am J Respir Crit Care Med. 2018. PMID: 30109950 Free PMC article.
BACKGROUND: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short- and long-term outcomes. Although remarkable progress has been made in the understanding of RV function and failure since the meeting o …
BACKGROUND: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short- a …
Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs.
Fernandez-Bustamante A, Klawitter J, Repine JE, Agazio A, Janocha AJ, Shah C, Moss M, Douglas IS, Tran ZV, Erzurum SC, Christians U, Seres T. Fernandez-Bustamante A, et al. Among authors: douglas is. Anesthesiology. 2014 Sep;121(3):469-81. doi: 10.1097/ALN.0000000000000301. Anesthesiology. 2014. PMID: 24809976 Free PMC article. Clinical Trial.
BACKGROUND: The early biological impact of short-term mechanical ventilation on healthy lungs is unknown. The authors aimed to characterize the immediate tidal volume (VT)-related changes on lung injury biomarkers in patients with healthy lungs and low risk of pulmonary co …
BACKGROUND: The early biological impact of short-term mechanical ventilation on healthy lungs is unknown. The authors aimed to charac …
A multicenter mortality prediction model for patients receiving prolonged mechanical ventilation.
Carson SS, Kahn JM, Hough CL, Seeley EJ, White DB, Douglas IS, Cox CE, Caldwell E, Bangdiwala SI, Garrett JM, Rubenfeld GD; ProVent Investigators. Carson SS, et al. Among authors: douglas is. Crit Care Med. 2012 Apr;40(4):1171-6. doi: 10.1097/CCM.0b013e3182387d43. Crit Care Med. 2012. PMID: 22080643 Free PMC article.
OBJECTIVE: Significant deficiencies exist in the communication of prognosis for patients requiring prolonged mechanical ventilation after acute illness, in part because of clinician uncertainty about long-term outcomes. We sought to refine a mortality prediction model for …
OBJECTIVE: Significant deficiencies exist in the communication of prognosis for patients requiring prolonged mechanical ventilation after ac …