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Neuroanatomical abnormalities in a nonhuman primate model of congenital Zika virus infection.
Beckman D, Seelke AMH, Bennett J, Dougherty P, Van Rompay KKA, Keesler R, Pesavento PA, Coffey LLA, Morrison JH, Bliss-Moreau E. Beckman D, et al. Among authors: dougherty p. Elife. 2022 Mar 9;11:e64734. doi: 10.7554/eLife.64734. Elife. 2022. PMID: 35261339 Free PMC article.
We evaluated neuropathological consequences of fetal ZIKV exposure in rhesus monkeys, a translatable animal model for human neural development, by carrying out quantitative neuroanatomical analyses of the nearly full-term brains of fetuses infected with ZIKV and procedure- …
We evaluated neuropathological consequences of fetal ZIKV exposure in rhesus monkeys, a translatable animal model for human neural developme …
Chemotherapy-induced peripheral neuropathy in a dish: dorsal root ganglion cells treated in vitro with paclitaxel show biochemical and physiological responses parallel to that seen in vivo.
Li Y, Marri T, North RY, Rhodes HR, Uhelski ML, Tatsui CE, Rhines LD, Rao G, Corrales G, Abercrombie TJ, Johansson CA, Dougherty PM. Li Y, et al. Among authors: dougherty pm. Pain. 2021 Jan;162(1):84-96. doi: 10.1097/j.pain.0000000000002005. Pain. 2021. PMID: 32694383 Free PMC article.
An important recent study has also shown that the initial toxicity produced by paclitaxel in patients was highly predictive of long-term outcome. In this study, we therefore focused on defining the mechanisms of acute toxicity produced by paclitaxel treatment on primary se …
An important recent study has also shown that the initial toxicity produced by paclitaxel in patients was highly predictive of long-term …
Motor Neuron Excitability Attenuation as a Sequel to Lumbosacral Manipulation in Subacute Low Back Pain Patients and Asymptomatic Adults: A Cross-Sectional H-Reflex Study.
Dishman JD, Burke JR, Dougherty P. Dishman JD, et al. Among authors: dougherty p. J Manipulative Physiol Ther. 2018 Jun;41(5):363-371. doi: 10.1016/j.jmpt.2017.10.015. Epub 2018 Jul 9. J Manipulative Physiol Ther. 2018. PMID: 29997032 Clinical Trial.
RESULTS: The time series analysis and the significant lumbosacral time interaction term (P < .05) indicated that inhibition of the H(max)/M(max) ratios at the 10-second postlumbosacral procedure time point was greatest after the HVLA SM procedure. ...

RESULTS: The time series analysis and the significant lumbosacral time interaction term (P < .05) indicated that inhibition of the

…
Radiation induces age-dependent deficits in cortical synaptic plasticity.
Zhang D, Zhou W, Lam TT, Weng C, Bronk L, Ma D, Wang Q, Duman JG, Dougherty PM, Grosshans DR. Zhang D, et al. Among authors: dougherty pm. Neuro Oncol. 2018 Aug 2;20(9):1207-1214. doi: 10.1093/neuonc/noy052. Neuro Oncol. 2018. PMID: 29660023 Free PMC article.
METHODS: In vivo recordings were used to test neuronal plasticity along the direct pathway from the cornu ammonis 1 (CA1)/subicular region to the prefrontal cortex (PFC). Specifically, long-term potentiation (LTP) in the CA1/subicular-PFC pathway was assessed after cranial …
METHODS: In vivo recordings were used to test neuronal plasticity along the direct pathway from the cornu ammonis 1 (CA1)/subicular region t …
The musculoskeletal effects of cigarette smoking.
Lee JJ, Patel R, Biermann JS, Dougherty PJ. Lee JJ, et al. Among authors: dougherty pj. J Bone Joint Surg Am. 2013 May 1;95(9):850-9. doi: 10.2106/JBJS.L.00375. J Bone Joint Surg Am. 2013. PMID: 23636193
Cigarette smoking decreases bone mineral density and increases the risk of sustaining a fracture or tendon injury, with partial reversibility of these risks with long-term cessation of smoking. Cigarette smoking increases the risk for perioperative complications, nonunion …
Cigarette smoking decreases bone mineral density and increases the risk of sustaining a fracture or tendon injury, with partial reversibilit …
Utility of early high dose statins in acute coronary syndrome.
Dougherty PJ, Arora RR. Dougherty PJ, et al. Am J Ther. 2012 Sep;19(5):369-76. doi: 10.1097/MJT.0b013e31823735aa. Am J Ther. 2012. PMID: 22964560 Review.
Our review suggests that early (<24 hours) high dose (80 mg of atorvastatin) statins may significantly reduce adverse cardiovascular outcomes and may improve long-term mortality....
Our review suggests that early (<24 hours) high dose (80 mg of atorvastatin) statins may significantly reduce adverse cardiovascular outc …
Spinal manipulative therapy for elderly patients with chronic obstructive pulmonary disease: a case series.
Dougherty PE, Engel RM, Vemulpad S, Burke J. Dougherty PE, et al. J Manipulative Physiol Ther. 2011 Jul-Aug;34(6):413-7. doi: 10.1016/j.jmpt.2011.05.004. Epub 2011 Jun 24. J Manipulative Physiol Ther. 2011. PMID: 21807266
METHODS: The study design was a prospective case series. Six patients of a long-term care center who were older than 65 years and having COPD underwent a course of 12 SMT sessions over a 4-week period. ...
METHODS: The study design was a prospective case series. Six patients of a long-term care center who were older than 65 years and hav …
Multiple traumatic limb loss: a comparison of Vietnam veterans to OIF/OEF servicemembers.
Dougherty PJ, McFarland LV, Smith DG, Esquenazi A, Blake DJ, Reiber GE. Dougherty PJ, et al. J Rehabil Res Dev. 2010;47(4):333-48. doi: 10.1682/jrrd.2009.04.0043. J Rehabil Res Dev. 2010. PMID: 20803402 Free article.
This article compares the Vietnam and the Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) groups with war-theater-associated multiple-limb loss to document significant changes in health status, prosthetic-device use, and long-term prognosis. During 2007 and 20 …
This article compares the Vietnam and the Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) groups with war-theater-associated mu …
Long-term follow-up of unilateral transfemoral amputees from the Vietnam war.
Dougherty PJ. Dougherty PJ. J Trauma. 2003 Apr;54(4):718-23. doi: 10.1097/01.TA.0000046260.16866.A9. J Trauma. 2003. PMID: 12707534
BACKGROUND: Despite their frequency, few reports exist concerning the initial and long-term consequences of battle-incurred unilateral transfemoral amputations. METHODS: A retrospective cohort design was used to measure the long-term health of transfemoral battle am …
BACKGROUND: Despite their frequency, few reports exist concerning the initial and long-term consequences of battle-incurred unilatera …
Physiological changes in primate somatosensory thalamus induced by deafferentation are dependent on the spinal funiculi that are sectioned and time following injury.
Weng HR, Lenz FA, Vierck C, Dougherty PM. Weng HR, et al. Among authors: dougherty pm. Neuroscience. 2003;116(4):1149-60. doi: 10.1016/s0306-4522(02)00796-0. Neuroscience. 2003. PMID: 12617956
A total of 1175 neurons were sampled from 13 animals, three intact, six with ventral quadrant lesions (three with prolonged survival and three with short-term survival after spinal lesion) and four with combined ventral and dorsal quadrant lesions. ...The magnitude of the …
A total of 1175 neurons were sampled from 13 animals, three intact, six with ventral quadrant lesions (three with prolonged survival and thr …
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