Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

6 results

Filters applied: . Clear all
Page 1
The human Papillomavirus twilight zone - Latency, immune control and subclinical infection.
Doorbar J. Doorbar J. Tumour Virus Res. 2023 Dec;16:200268. doi: 10.1016/j.tvr.2023.200268. Epub 2023 Jun 23. Tumour Virus Res. 2023. PMID: 37354969 Free PMC article. Review.
Clinical studies, and animal model infection studies, suggested a key role for host immune surveillance in maintaining such asymptomatic infections, and although infections may also be cleared, most studies have used the term 'clearance' to describe a situation where the p …
Clinical studies, and animal model infection studies, suggested a key role for host immune surveillance in maintaining such asymptomatic inf …
Modulation of basal cell fate during productive and transforming HPV-16 infection is mediated by progressive E6-driven depletion of Notch.
Kranjec C, Holleywood C, Libert D, Griffin H, Mahmood R, Isaacson E, Doorbar J. Kranjec C, et al. Among authors: doorbar j. J Pathol. 2017 Aug;242(4):448-462. doi: 10.1002/path.4917. J Pathol. 2017. PMID: 28497579 Free PMC article.
Inactivating mutations in key driver genes, such as TP53 and NOTCH1, reduce the proportion of differentiating cells allowing for the long-term persistence of expanding mutant clones in the tissue. Here we show that through the expression of E6, HPV-16 prevents the early fa …
Inactivating mutations in key driver genes, such as TP53 and NOTCH1, reduce the proportion of differentiating cells allowing for the long- …
The low-risk papillomaviruses.
Egawa N, Doorbar J. Egawa N, et al. Among authors: doorbar j. Virus Res. 2017 Mar 2;231:119-127. doi: 10.1016/j.virusres.2016.12.017. Epub 2016 Dec 28. Virus Res. 2017. PMID: 28040475 Free article. Review.
These viruses are referred to as 'high-risk' (hrHPV), to distinguish them from the over 200 prevalent HPV types that more commonly cause only benign epithelial lesions. The 'low-risk' (lrHPV) term used to describe this group belies their cumulative morbidity. ...
These viruses are referred to as 'high-risk' (hrHPV), to distinguish them from the over 200 prevalent HPV types that more commonly cause onl …
Carcinogenic human papillomavirus infection.
Schiffman M, Doorbar J, Wentzensen N, de Sanjosé S, Fakhry C, Monk BJ, Stanley MA, Franceschi S. Schiffman M, et al. Among authors: doorbar j. Nat Rev Dis Primers. 2016 Dec 1;2:16086. doi: 10.1038/nrdp.2016.86. Nat Rev Dis Primers. 2016. PMID: 27905473 Review.
The discovery of HPV as a carcinogen led to the development of effective preventive vaccines and sensitive HPV DNA and RNA tests. Together, vaccination programmes (the ultimate long-term preventive strategy) and screening using HPV tests could dramatically alter the landsc …
The discovery of HPV as a carcinogen led to the development of effective preventive vaccines and sensitive HPV DNA and RNA tests. Together, …
Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia.
Egawa N, Egawa K, Griffin H, Doorbar J. Egawa N, et al. Among authors: doorbar j. Viruses. 2015 Jul 16;7(7):3863-90. doi: 10.3390/v7072802. Viruses. 2015. PMID: 26193301 Free PMC article. Review.
Many papillomaviruses minimise the risk of immune clearance by causing chronic asymptomatic infections, accompanied by long-term virion-production with only limited viral gene expression. Such lesions are typical of those caused by Beta HPV types in the general population, …
Many papillomaviruses minimise the risk of immune clearance by causing chronic asymptomatic infections, accompanied by long-term viri …
Characterization of events during the late stages of HPV16 infection in vivo using high-affinity synthetic Fabs to E4.
Doorbar J, Foo C, Coleman N, Medcalf L, Hartley O, Prospero T, Napthine S, Sterling J, Winter G, Griffin H. Doorbar J, et al. Virology. 1997 Nov 10;238(1):40-52. doi: 10.1006/viro.1997.8768. Virology. 1997. PMID: 9375007 Free article.
A C-terminal monoclonal (TVG404) was generated by hybridoma technology, and N-terminal polyclonal antiserum was prepared by peptide immunization (alpha N-term). The most potent antibody (TVG405) had an affinity for E4 of approximately 1.0 nM. ...
A C-terminal monoclonal (TVG404) was generated by hybridoma technology, and N-terminal polyclonal antiserum was prepared by peptide immuniza …