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Inappropriate prescribing contributes to high antibiotic exposure in young children in Australia.
Netea SA, Messina NL, Gardiner K, Pittet LF, Curtis N; MIS BAIR trial consortium. Netea SA, et al. J Antimicrob Chemother. 2024 Apr 17:dkae090. doi: 10.1093/jac/dkae090. Online ahead of print. J Antimicrob Chemother. 2024. PMID: 38629145
BACKGROUND: Antibiotic exposure increases antimicrobial resistance and has also been associated with long-term harms, including allergies, inflammatory diseases and weight gain. ...Factors associated with antibiotic exposure from 0 to 12 months of age were delivery by Caes …
BACKGROUND: Antibiotic exposure increases antimicrobial resistance and has also been associated with long-term harms, including aller …
Intratracheal budesonide mixed with surfactant to increase survival free of bronchopulmonary dysplasia in extremely preterm infants: statistical analysis plan for the international, multicenter, randomized PLUSS trial.
Francis KL, McKinlay CJD, Kamlin COF, Cheong JLY, Dargaville PA, Dawson JA, Doyle LW, Jacobs SE, Davis PG, Donath SM, Manley BJ. Francis KL, et al. Among authors: donath sm. Trials. 2023 Nov 6;24(1):709. doi: 10.1186/s13063-023-07650-0. Trials. 2023. PMID: 37932774 Free PMC article. Clinical Trial.
Effective and safe prophylactic therapies for BPD are urgently required. Systemic corticosteroids reduce rates of BPD in the short term but are associated with poorer neurodevelopmental outcomes if given to ventilated infants in the first week after birth. ...Second …
Effective and safe prophylactic therapies for BPD are urgently required. Systemic corticosteroids reduce rates of BPD in the short term
Intratracheal budesonide mixed with surfactant to increase survival free of bronchopulmonary dysplasia in extremely preterm infants: study protocol for the international, multicenter, randomized PLUSS trial.
Manley BJ, Kamlin COF, Donath S, Huang L, Birch P, Cheong JLY, Dargaville PA, Dawson JA, Doyle LW, Jacobs SE, Wilson R, Davis PG, McKinlay CJD. Manley BJ, et al. Among authors: donath s. Trials. 2023 May 9;24(1):320. doi: 10.1186/s13063-023-07257-5. Trials. 2023. PMID: 37161488 Free PMC article.
Effective and safe prophylactic therapies for BPD are urgently required. Systemic corticosteroids reduce rates of BPD in the short-term but are associated with poorer neurodevelopmental outcomes if given to ventilated infants in the first week after birth. ...METHOD …
Effective and safe prophylactic therapies for BPD are urgently required. Systemic corticosteroids reduce rates of BPD in the short-term
Physiologically based cord clamping for infants ≥32+0 weeks gestation: A randomised clinical trial and reference percentiles for heart rate and oxygen saturation for infants ≥35+0 weeks gestation.
Badurdeen S, Davis PG, Hooper SB, Donath S, Santomartino GA, Heng A, Zannino D, Hoq M, Omar F Kamlin C, Kane SC, Woodward A, Roberts CT, Polglase GR, Blank DA; Baby Directed Umbilical Cord Clamping (BabyDUCC) collaborative group. Badurdeen S, et al. Among authors: donath s. PLoS Med. 2022 Jun 23;19(6):e1004029. doi: 10.1371/journal.pmed.1004029. eCollection 2022 Jun. PLoS Med. 2022. PMID: 35737735 Free PMC article. Clinical Trial.
BACKGROUND: Globally, the majority of newborns requiring resuscitation at birth are full term or late-preterm infants. These infants typically have their umbilical cord clamped early (ECC) before moving to a resuscitation platform, losing the potential support of th …
BACKGROUND: Globally, the majority of newborns requiring resuscitation at birth are full term or late-preterm infants. These i …
Symptom relief, prognostic factors, and outcome in patients receiving urgent radiation therapy for superior vena cava syndrome : A single-center retrospective analysis of 21 years' practice.
Guhlich M, Maag TE, Dröge LH, El Shafie RA, Hille A, Donath S, Schirmer MA, Knaus O, Nauck F, Overbeck TR, Hinterthaner M, Körber W, Andreas S, Rittmeyer A, Leu M, Rieken S. Guhlich M, et al. Among authors: donath s. Strahlenther Onkol. 2022 Dec;198(12):1072-1081. doi: 10.1007/s00066-022-01952-z. Epub 2022 May 12. Strahlenther Onkol. 2022. PMID: 35552767 Free PMC article.

Symptom relief was achieved in 68.4%. Mean OS was 59 days, 7.6% (n = 6) of patients showed long-term survival (> 2 years). Applied RT dose > 39 Gy, clinical target volume (CTV) size < 387 ml, concomitant chemotherapy, and completion of the prescribed RT course wer

Symptom relief was achieved in 68.4%. Mean OS was 59 days, 7.6% (n = 6) of patients showed long-term survival (> 2 years). Applied …
Neonatal head injuries: A prospective Paediatric Research in Emergency Departments International Collaborative cohort study.
Eapen N, Borland ML, Phillips N, Kochar A, Dalton S, Cheek JA, Gilhotra Y, Neutze J, Lyttle MD, Donath S, Crowe L, Dalziel SR, Oakley E, Williams A, Hearps S, Bressan S, Babl FE. Eapen N, et al. Among authors: donath s. J Paediatr Child Health. 2020 May;56(5):764-769. doi: 10.1111/jpc.14736. Epub 2019 Dec 23. J Paediatr Child Health. 2020. PMID: 31868278
AIM: To characterise the causes, clinical characteristics and short-term outcomes of neonates who presented to paediatric emergency departments with a head injury. ...CONCLUSIONS: Neonatal head injuries are rare with a mostly benign short-term outcome and are approp …
AIM: To characterise the causes, clinical characteristics and short-term outcomes of neonates who presented to paediatric emergency d …
A prospective, cross-sectional study to establish age-specific reference intervals for neonates and children in the setting of clinical biochemistry, immunology and haematology: the HAPPI Kids study protocol.
Hoq M, Karlaftis V, Mathews S, Burgess J, Donath SM, Carlin J, Monagle P, Ignjatovic V. Hoq M, et al. Among authors: donath sm. BMJ Open. 2019 Apr 3;9(4):e025897. doi: 10.1136/bmjopen-2018-025897. BMJ Open. 2019. PMID: 30948591 Free PMC article.
Venous blood samples are collected from healthy premature neonates (32-36 weeks of gestation), term neonates (from birth to a maximum of 72 hours postbirth) and children aged 30 days to 18 years (undergoing minor day surgical procedures). ...
Venous blood samples are collected from healthy premature neonates (32-36 weeks of gestation), term neonates (from birth to a …
Long-term clinical and immunological effects of probiotic and peanut oral immunotherapy after treatment cessation: 4-year follow-up of a randomised, double-blind, placebo-controlled trial.
Hsiao KC, Ponsonby AL, Axelrad C, Pitkin S, Tang MLK; PPOIT Study Team. Hsiao KC, et al. Lancet Child Adolesc Health. 2017 Oct;1(2):97-105. doi: 10.1016/S2352-4642(17)30041-X. Epub 2017 Aug 15. Lancet Child Adolesc Health. 2017. PMID: 30169215
BACKGROUND: Oral immunotherapy has attracted much interest as a potential treatment for food allergy, yet little is known about its long-term effects. We aimed to assess long-term outcomes in participants who completed a randomised, double-blind, placebo-controlled …
BACKGROUND: Oral immunotherapy has attracted much interest as a potential treatment for food allergy, yet little is known about its long- …
Probiotics, prematurity and neurodevelopment: follow-up of a randomised trial.
Jacobs SE, Hickey L, Donath S, Opie GF, Anderson PJ, Garland SM, Cheong JLY; ProPremsStudy Groups. Jacobs SE, et al. Among authors: donath s. BMJ Paediatr Open. 2017 Nov 25;1(1):e000176. doi: 10.1136/bmjpo-2017-000176. eCollection 2017. BMJ Paediatr Open. 2017. PMID: 29637171 Free PMC article.
INTERVENTION: Probiotics (Bifidobacterium infantis, Streptococcus thermophilus and Bifidobacterium lactis) or placebo administered from birth until discharge home or term CA, whichever came sooner. MAIN OUTCOME MEASURES: Major neurodevelopmental impairment comprised …
INTERVENTION: Probiotics (Bifidobacterium infantis, Streptococcus thermophilus and Bifidobacterium lactis) or placebo administered from b
38 results