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MRI and pathology comparisons in Rasmussen's encephalitis: a multi-institutional examination of hemispherotomy outcomes relative to imaging and histological severity.
Doherty A, Knudson K, Fuller C, Leach JL, Wang AC, Marupudi N, Han RH, Tomko S, Ojemann J, Smyth MD, Mangano F, Skoch J. Doherty A, et al. Childs Nerv Syst. 2024 Mar 15. doi: 10.1007/s00381-024-06353-4. Online ahead of print. Childs Nerv Syst. 2024. PMID: 38489033
Hemispherotomy provides the best chance at achieving seizure freedom in RE patients, but with significant risks and variable long-term outcomes. The goal of this study is to utilize our multicenter pediatric cohort to characterize if differences in pathology and/or imaging …
Hemispherotomy provides the best chance at achieving seizure freedom in RE patients, but with significant risks and variable long-term
Patient-Reported Outcomes 12 Years after Localized Prostate Cancer Treatment.
Donovan JL, Hamdy FC, Lane JA, Young GJ, Metcalfe C, Walsh EI, Davis M, Steuart-Feilding T, Blazeby JM, Avery KNL, Martin RM, Bollina P, Doble A, Doherty A, Gillatt D, Gnanapragasam V, Hughes O, Kockelbergh R, Kynaston H, Paul A, Paez E, Powell P, Rosario DJ, Rowe E, Mason M, Catto JWF, Peters TJ, Wade J, Turner EL, Williams NJ, Oxley J, Staffurth J, Bryant RJ, Neal DE. Donovan JL, et al. Among authors: doherty a. NEJM Evid. 2023 Apr;2(4):EVIDoa2300018. doi: 10.1056/EVIDoa2300018. Epub 2023 Mar 11. NEJM Evid. 2023. PMID: 38320051
Outcomes after Localized Prostate Cancer TreatmentDonovan et al. present the long-term patient-reported outcomes of 1643 randomly assigned participants in the ProtecT (Prostate Testing for Cancer and Treatment) trial. ...
Outcomes after Localized Prostate Cancer TreatmentDonovan et al. present the long-term patient-reported outcomes of 1643 randomly ass …
Determinants of workload-related clinician stress levels in general hospital consultation liaison psychiatry services during the COVID-19 pandemic in England and Ireland. Short report.
van der Feltz-Cornelis CM, Sweetman J, Lee W, Doherty AM, Dineen P, Meinlschmidt G, Vitinius F, Fazekas C, Huber CG, Schaefert R, Stein B. van der Feltz-Cornelis CM, et al. Among authors: doherty am. J Psychosom Res. 2024 Feb;177:111584. doi: 10.1016/j.jpsychores.2023.111584. Epub 2023 Dec 30. J Psychosom Res. 2024. PMID: 38181547 Free article.
Rigorous measures may be needed to ensure mental healthcare provision remains tenable and sustainable in the long term....
Rigorous measures may be needed to ensure mental healthcare provision remains tenable and sustainable in the long term....
Knowledge Retention From Emergency Medicine Simulation-Based Learning Curriculum for Pre-clinical Medical Students.
McMains JC, Larkins MC, Doherty AM, Horiates J, Alachraf K, Gordon JA, Fletcher J, Brewer KL. McMains JC, et al. Among authors: doherty am. Cureus. 2023 Jun 30;15(6):e41216. doi: 10.7759/cureus.41216. eCollection 2023 Jun. Cureus. 2023. PMID: 37525818 Free PMC article.
Retention of factual knowledge is a current topic of discussion as medical learners often have difficulty with long-term retention. The aim of this study was to assess if students would learn, retain, and enjoy emergency medicine (EM)-focused SBL. ...
Retention of factual knowledge is a current topic of discussion as medical learners often have difficulty with long-term retention. T …
Longitudinal characterization of TK6 cells sequentially adapted to animal product-free, chemically defined culture medium: considerations for genotoxicity studies.
Perez-Diaz N, Hoffman E, Clements J, Cruickshank R, Doherty A, Ebner D, Elloway J, Fu J, Kelsall J, Millar V, Saib O, Scott A, Woods I, Hutter V. Perez-Diaz N, et al. Among authors: doherty a. Front Toxicol. 2023 Jul 4;5:1177586. doi: 10.3389/ftox.2023.1177586. eCollection 2023. Front Toxicol. 2023. PMID: 37469456 Free PMC article.
Several chemically defined serum replacements (CDSR) have been developed to provide an alternative to FBS, but not every cell line adapts easily and successfully to CDSR-supplemented medium, and the long-term effect on cell characteristics remains uncertain. Aim: The aim o …
Several chemically defined serum replacements (CDSR) have been developed to provide an alternative to FBS, but not every cell line adapts ea …
Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer.
Hamdy FC, Donovan JL, Lane JA, Metcalfe C, Davis M, Turner EL, Martin RM, Young GJ, Walsh EI, Bryant RJ, Bollina P, Doble A, Doherty A, Gillatt D, Gnanapragasam V, Hughes O, Kockelbergh R, Kynaston H, Paul A, Paez E, Powell P, Rosario DJ, Rowe E, Mason M, Catto JWF, Peters TJ, Oxley J, Williams NJ, Staffurth J, Neal DE; ProtecT Study Group. Hamdy FC, et al. Among authors: doherty a. N Engl J Med. 2023 Apr 27;388(17):1547-1558. doi: 10.1056/NEJMoa2214122. Epub 2023 Mar 11. N Engl J Med. 2023. PMID: 36912538 Clinical Trial.
METHODS: At a median follow-up of 15 years (range, 11 to 21), we compared the results in this population with respect to death from prostate cancer (the primary outcome) and death from any cause, metastases, disease progression, and initiation of long-term androgen-depriva …
METHODS: At a median follow-up of 15 years (range, 11 to 21), we compared the results in this population with respect to death from prostate …
Substance use and self-harm emergency department presentations during COVID19: evidence from a National Clinical Programme for Self-Harm.
Maguire E, Kavalidou K, Bannan N, Doherty AM, Jeffers A. Maguire E, et al. Among authors: doherty am. Ir J Psychol Med. 2023 Sep;40(3):424-429. doi: 10.1017/ipm.2022.36. Epub 2022 Aug 2. Ir J Psychol Med. 2023. PMID: 35915057
CONCLUSION: An increase in suicide-related ideation and substance-related self-harm presentations may indicate longer term effects of the pandemic and its relevant restrictions. Future studies might explore whether those presenting with ideation will develop a risk of suic …
CONCLUSION: An increase in suicide-related ideation and substance-related self-harm presentations may indicate longer term effects of …
The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project.
Flynn J, O'Connor L, Hanlon M, Bellani G, Contreras M, Doherty A, Durand H, Fallon E, Gormley C, Laffey J, Molloy G, Sarma K, Strepparava MG, Russo S, Walsh J, McGuire BE. Flynn J, et al. Among authors: doherty a. HRB Open Res. 2021 Jan 29;3:54. doi: 10.12688/hrbopenres.13117.2. eCollection 2020. HRB Open Res. 2021. PMID: 33870088 Free PMC article.
Accordingly, this project will employ a mixed-methods approach over three work packages to develop best-practice guidelines for alleviating psychological distress in FLWs during the different phases of the pandemic. Work package 1 will identify the point and long-term prev …
Accordingly, this project will employ a mixed-methods approach over three work packages to develop best-practice guidelines for alleviating …
Men's experiences of radiotherapy treatment for localized prostate cancer and its long-term treatment side effects: a longitudinal qualitative study.
Sutton E, Lane JA, Davis M, Walsh EI, Neal DE, Hamdy FC, Mason M, Staffurth J, Martin RM, Metcalfe C, Peters TJ, Donovan JL, Wade J; ProtecT Study Group. Sutton E, et al. Cancer Causes Control. 2021 Mar;32(3):261-269. doi: 10.1007/s10552-020-01380-3. Epub 2021 Jan 4. Cancer Causes Control. 2021. PMID: 33394204 Free PMC article.
RESULTS: Men experienced bowel, sexual, and urinary side effects, mostly in the short term but some persisted and were bothersome. Most men downplayed the impacts, voicing expectations of age-related decline, and normalizing these changes. ...CONCLUSIONS: These findings re …
RESULTS: Men experienced bowel, sexual, and urinary side effects, mostly in the short term but some persisted and were bothersome. Mo …
An exploration of lifestyle/obesity programmes for adults with intellectual disabilities through a realist lens: Impact of a 'context, mechanism and outcome' evaluation.
Taggart L, Doherty AJ, Chauhan U, Hassiotis A. Taggart L, et al. Among authors: doherty aj. J Appl Res Intellect Disabil. 2021 Mar;34(2):578-593. doi: 10.1111/jar.12826. Epub 2020 Dec 20. J Appl Res Intellect Disabil. 2021. PMID: 33342030
RESULTS: There were few theoretically underpinned, multi-component programmes that were effective in the short to long-term and many failed to explore the 'context and mechanisms'. We developed a logic model and engaged in two co-production workshops to refine this model. …
RESULTS: There were few theoretically underpinned, multi-component programmes that were effective in the short to long-term and many …
36 results