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Page 1
Eradication of measles: remaining challenges.
Holzmann H, Hengel H, Tenbusch M, Doerr HW. Holzmann H, et al. Among authors: doerr hw. Med Microbiol Immunol. 2016 Jun;205(3):201-8. doi: 10.1007/s00430-016-0451-4. Epub 2016 Mar 2. Med Microbiol Immunol. 2016. PMID: 26935826 Free PMC article. Review.
In addition, MeV infections cause long-lasting memory B and T cell impairment, predisposing people susceptible to opportunistic infections for years. A rare, but fatal long-term consequence of measles is subacute sclerosing panencephalitis. ...
In addition, MeV infections cause long-lasting memory B and T cell impairment, predisposing people susceptible to opportunistic infections f …
The complexity of aging: cancer risk among elderly people and infectious risk among those with cancer.
Pinzone MR, Berretta M, Doerr HW, Nunnari G, Cacopardo B. Pinzone MR, et al. Among authors: doerr hw. Anticancer Agents Med Chem. 2013 Nov;13(9):1444-8. doi: 10.2174/18715206113136660346. Anticancer Agents Med Chem. 2013. PMID: 24102281 Review.
Co-existing medical conditions, e.g. chronic renal failure, diabetes mellitus, emphysema, which are quite common in the elderly, may also contribute to rising the infectious risk, as well as the use of long term vascular catheters, which is required in a large number of ca …
Co-existing medical conditions, e.g. chronic renal failure, diabetes mellitus, emphysema, which are quite common in the elderly, may also co …
Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection.
Michaelis M, Barth S, Breitling R, Bruch J, Steinberger D, Rothweiler F, Hackmann K, Schröck E, Doerr HW, Griffin DK, Cinatl J, Cinatl J Jr. Michaelis M, et al. Among authors: doerr hw. Oncogenesis. 2012 Apr 30;1(4):e10. doi: 10.1038/oncsis.2012.10. Oncogenesis. 2012. PMID: 23552602 Free PMC article.
Here, we investigated whether the prolonged presence of HCMV can result in the irreversible selection of a cancer cell population with increased malignancy. The neuroblastoma cell line UKF-NB-4 was long-term (200 passages) infected with the HCMV strain Hi91 (UKF-NB-4(Hi)) …
Here, we investigated whether the prolonged presence of HCMV can result in the irreversible selection of a cancer cell population with incre …
Does short-term virologic failure translate to clinical events in antiretroviral-naive patients initiating antiretroviral therapy in clinical practice?
Antiretroviral Therapy Cohort Collaboration (ART-CC); Mugavero MJ, May M, Harris R, Saag MS, Costagliola D, Egger M, Phillips A, Günthard HF, Dabis F, Hogg R, de Wolf F, Fatkenheuer G, Gill MJ, Justice A, D'Arminio Monforte A, Lampe F, Miró JM, Staszewski S, Sterne JA. Antiretroviral Therapy Cohort Collaboration (ART-CC), et al. AIDS. 2008 Nov 30;22(18):2481-92. doi: 10.1097/QAD.0b013e328318f130. AIDS. 2008. PMID: 19005271 Free PMC article.
OBJECTIVE: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens translate to differences in clinical events in antiretroviral-naive patients initiating ART. ...CONCLUSION: Among antiretroviral-naive pati …
OBJECTIVE: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens …
[Influenza: acceptance of vaccination by healthcare personnel. Evaluation of the influenza season 2006/2007].
Wicker S, Doerr HW, Gottschalk R, Rabenau HF, Allwinn R. Wicker S, et al. Among authors: doerr hw. Dtsch Med Wochenschr. 2007 Aug;132(33):1683-7. doi: 10.1055/s-2007-984949. Dtsch Med Wochenschr. 2007. PMID: 17713863 German.
CONCLUSION: In spite of an extensive vaccination campaign and a significantly increased vaccination rate of the personnel (3.5% in 2001/2002; 25.8% in 2006/2007), the acceptance of influenza vaccination remains low. Long-term measures are required to obtain better rates fo …
CONCLUSION: In spite of an extensive vaccination campaign and a significantly increased vaccination rate of the personnel (3.5% in 2001/2002 …
Quadruple nucleoside therapy with zidovudine, lamivudine, abacavir and tenofovir in the treatment of HIV.
Stürmer M, Staszewski S, Doerr HW. Stürmer M, et al. Among authors: doerr hw. Antivir Ther. 2007;12(5):695-703. Antivir Ther. 2007. PMID: 17713153 Review.
Highly active antiretroviral therapy (HAART) has significantly reduced morbidity and mortality in HIV-infected patients. However, problems such as short-term or long-term toxicity and the development of drug resistance could necessitate a change in the therapy regim …
Highly active antiretroviral therapy (HAART) has significantly reduced morbidity and mortality in HIV-infected patients. However, problems s …
Evolution of resistance mutations during low-level viral replication in HIV-1-infected patients treated with zidovudine/lamivudine/abacavir as a first-line regimen.
Stürmer M, Dauer B, Moesch M, Haberl A, Mueller A, Locher L, Knecht G, Hanke N, Doerr HW, Staszewski S. Stürmer M, et al. Among authors: doerr hw. Antivir Ther. 2007;12(1):25-30. doi: 10.1177/135965350701200102. Antivir Ther. 2007. PMID: 17503744
OBJECTIVE: Long-term evaluation of viral evolution in patients who continued first-line therapy with zidovudine/lamivudine/abacavir (Trizivir [TZV]) in the presence of low-level viral replication and assessment of the impact of mutational patterns selected under TZV on vir …
OBJECTIVE: Long-term evaluation of viral evolution in patients who continued first-line therapy with zidovudine/lamivudine/abacavir ( …
Durability of HIV-1 viral suppression over 3.3 years with multi-drug antiretroviral therapy in previously drug-naive individuals.
Phillips AN, Miller V, Sabin C, Cozzi Lepri A, Klauke S, Bickel M, Doerr HW, Hill A, Staszewski S. Phillips AN, et al. Among authors: doerr hw. AIDS. 2001 Dec 7;15(18):2379-84. doi: 10.1097/00002030-200112070-00005. AIDS. 2001. PMID: 11740188 Clinical Trial.
BACKGROUND: Relatively little is known about the long-term durability of viral suppression in individuals initially achieving a viral load of less than 50 copies/ml within 24 weeks of starting antiretroviral therapy, nor the extent to which therapy interruption accounts fo …
BACKGROUND: Relatively little is known about the long-term durability of viral suppression in individuals initially achieving a viral …
The role of viral load determination for the management of human immunodeficiency virus, hepatitis B virus and hepatitis C virus infection.
Berger A, Preiser W, Doerr HW. Berger A, et al. Among authors: doerr hw. J Clin Virol. 2001 Jan;20(1-2):23-30. doi: 10.1016/s1386-6532(00)00151-7. J Clin Virol. 2001. PMID: 11163579 Review.
The prognostic relevance of quantitative HCV RNA determination is of limited value for the long-term prognosis of chronic hepatitis C. However, viral load may predict the outcome of antiviral therapy. ...
The prognostic relevance of quantitative HCV RNA determination is of limited value for the long-term prognosis of chronic hepatitis C …
Azidothymidine resistance of H9 human T-cell lymphoma cells is associated with decreased sensitivity to antitumor agents and inhibition of apoptosis.
Cinatl J Jr, Kotchetkov R, Gröschel B, Cinatl J, Driever PH, Kabickova H, Kornhuber B, Schwabe D, Doerr HW. Cinatl J Jr, et al. Among authors: doerr hw. Int J Mol Med. 1998 Dec;2(6):685-91. doi: 10.3892/ijmm.2.6.685. Int J Mol Med. 1998. PMID: 9850737
In addition the development of tumors and their response to therapy may be further influenced by long-term treatment of HIV-1 patients with nucleoside analogs such as AZT (3'-azido-3'deoxythymidine), ddI (2',3'-dideoxyinosine), ddC (2',3'-dideoxycytidine), d4T (2',3'-dideh …
In addition the development of tumors and their response to therapy may be further influenced by long-term treatment of HIV-1 patient …
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