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Cytoprotective effect of tocopherols in hepatocytes cultured with polyunsaturated fatty acids.
Mikkelsen L, Hansen HS, Grunnet N, Dich J. Mikkelsen L, et al. Among authors: dich j. Lipids. 1994 May;29(5):369-72. doi: 10.1007/BF02537192. Lipids. 1994. PMID: 8015369
To find an optimal antioxidant for this purpose, the effect of 50 microM alpha-tocopherol, gamma-tocopherol, alpha-tocopheryl acetate, alpha-tocopheryl acid succinate, or alpha-tocopheryl phosphate, or of 1 microM N,N'-diphenyl-1,4-phenylenediamine, was investigated with respect …
To find an optimal antioxidant for this purpose, the effect of 50 microM alpha-tocopherol, gamma-tocopherol, alpha-tocopheryl acetate, alpha …
Inhibition of fatty acid synthesis in rat hepatocytes by exogenous polyunsaturated fatty acids is caused by lipid peroxidation.
Mikkelsen L, Hansen HS, Grunnet N, Dich J. Mikkelsen L, et al. Among authors: dich j. Biochim Biophys Acta. 1993 Feb 10;1166(1):99-104. doi: 10.1016/0005-2760(93)90289-l. Biochim Biophys Acta. 1993. PMID: 8431498
Rat hepatocyte long-term cultures were utilized to investigate the impact of different polyunsaturated fatty acids (PUFA) on the insulin-induced de novo fatty acid synthesis in vitro. ...
Rat hepatocyte long-term cultures were utilized to investigate the impact of different polyunsaturated fatty acids (PUFA) on the insu …
Long-term culture of hepatocytes: effect of hormones on enzyme activities and metabolic capacity.
Dich J, Vind C, Grunnet N. Dich J, et al. Hepatology. 1988 Jan-Feb;8(1):39-45. doi: 10.1002/hep.1840080109. Hepatology. 1988. PMID: 3276589
(vii) It is concluded that hepatocyte cultures as described in the present study may be a useful, well-defined system for long-term metabolic, pharmacologic and toxicologic studies....
(vii) It is concluded that hepatocyte cultures as described in the present study may be a useful, well-defined system for long-term m …
Effect of ethanol on lipid metabolism in cultured hepatocytes.
Grunnet N, Kondrup J, Dich J. Grunnet N, et al. Among authors: dich j. Biochem J. 1985 Jun 15;228(3):673-81. doi: 10.1042/bj2280673. Biochem J. 1985. PMID: 3927897 Free PMC article.
After this period the medium was changed again and the cultures were further incubated with [1-14C]oleate alone or with [1-14C]oleate plus ethanol for 6 h. This allowed a comparison of effects of short-term (6 h) and long-term (24 + 6 h) exposure to ethanol on fatty …
After this period the medium was changed again and the cultures were further incubated with [1-14C]oleate alone or with [1-14C]oleate plus e …