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Stability of carboplatin and oxaliplatin in their infusion solutions is due to self-association.
Di Pasqua AJ, Kerwood DJ, Shi Y, Goodisman J, Dabrowiak JC. Di Pasqua AJ, et al. Dalton Trans. 2011 May 14;40(18):4821-5. doi: 10.1039/c0dt01758b. Epub 2011 Apr 4. Dalton Trans. 2011. PMID: 21461444
The work presented here shows that carboplatin and oxaliplatin mainly exist as association complexes in concentrated aqueous solution, a property that accounts for the long term stability of their ready-to-use infusion solutions, and that these association complexes may ex …
The work presented here shows that carboplatin and oxaliplatin mainly exist as association complexes in concentrated aqueous solution, a pro …