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Palliative needs for heart failure or chronic obstructive pulmonary disease: Results of a multicenter observational registry.
Int J Cardiol. 2015 Apr 1;184:552-558. doi: 10.1016/j.ijcard.2015.03.056. Epub 2015 Mar 5.
Int J Cardiol. 2015.
PMID: 25767016
Free article.
METHODS AND RESULTS: Seven centers enrolled 267 patients with advanced HF (n=174) or COPD (n=93) using common (multiple hospitalizations or severely impaired functional status or cachexia) and disease-specific (HF: systolic dysfunction, NYHA classes III-IV, end-organ hypoperfusio …
METHODS AND RESULTS: Seven centers enrolled 267 patients with advanced HF (n=174) or COPD (n=93) using common (multiple hospitalizations or …
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
Linke SP, Clarkin KC, Di Leonardo A, Tsou A, Wahl GM.
Linke SP, et al. Among authors: di leonardo a.
Genes Dev. 1996 Apr 15;10(8):934-47. doi: 10.1101/gad.10.8.934.
Genes Dev. 1996.
PMID: 8608941
Free article.
In contrast to the p53-dependent response to DNA damage, characterized by long-term arrest and irregular cellular morphologies, the antimetabolite-induced arrest was highly reversible and cellular morphologies remained relatively normal. ...
In contrast to the p53-dependent response to DNA damage, characterized by long-term arrest and irregular cellular morphologies, the a …
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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.
Di Leonardo A, Linke SP, Clarkin K, Wahl GM.
Di Leonardo A, et al.
Genes Dev. 1994 Nov 1;8(21):2540-51. doi: 10.1101/gad.8.21.2540.
Genes Dev. 1994.
PMID: 7958916
Free article.
Cytogenetic analyses combined with radiation dosage data indicate that only one or a small number of unrepaired DNA breaks may be sufficient to cause arrest. The arrest also correlated with long-term elevations of p53 protein, Cip1 mRNA, and Cip1 protein. We propose that p …
Cytogenetic analyses combined with radiation dosage data indicate that only one or a small number of unrepaired DNA breaks may be sufficient …
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