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Real-life omalizumab exposure and discontinuation in a large nationwide population-based study of paediatric and adult asthma patients.
Humbert M, Bourdin A, Taillé C, Kamar D, Thonnelier C, Lajoinie A, Rigault A, Deschildre A, Molimard M. Humbert M, et al. Among authors: deschildre a. Eur Respir J. 2022 Nov 10;60(5):2103130. doi: 10.1183/13993003.03130-2021. Print 2022 Nov. Eur Respir J. 2022. PMID: 35618272 Free PMC article.
CONCLUSION: This is the first large-scale study describing omalizumab real-life exposure patterns in adult and paediatric asthma patients in France with >10 years of follow-up. We showed the long-term maintenance of low HCRU in adults and children who discontinued omali …
CONCLUSION: This is the first large-scale study describing omalizumab real-life exposure patterns in adult and paediatric asthma patients in …
Biologicals in childhood severe asthma: the European PERMEABLE survey on the status quo.
Santos-Valente E, Buntrock-Döpke H, Abou Taam R, Arasi S, Bakirtas A, Lozano Blasco J, Bønnelykke K, Craiu M, Cutrera R, Deschildre A, Elnazir B, Fleming L, Frey U, Gappa M, Nieto García A, Skamstrup Hansen K, Hanssens L, Jahnz-Rozyk K, Jesenak M, Kerzel S, Kopp MV, Koppelman GH, Krivec U, MacLeod KA, Mäkelä M, Melén E, Mezei G, Moeller A, Moreira A, Pohunek P, Minić P, Rutjes NWP, Sammut P, Schwerk N, Szépfalusi Z, Turkalj M, Tzotcheva I, Ulmeanu A, Verhulst S, Xepapadaki P, Niggel J, Vijverberg S, Maitland-van der Zee AH, Potočnik U, Reinartz SM, van Drunen CM, Kabesch M. Santos-Valente E, et al. Among authors: deschildre a. ERJ Open Res. 2021 Aug 16;7(3):00143-2021. doi: 10.1183/23120541.00143-2021. eCollection 2021 Jul. ERJ Open Res. 2021. PMID: 34409097 Free PMC article.
Predicting the risk of respiratory distress in newborns with congenital pulmonary malformations.
Delacourt C, Bertille N, Salomon LJ, Rahshenas M, Benachi A, Bonnard A, Choupeaux L, Fouquet V, Goua V, Hameury F, Hervieux E, Jouannic JM, Khen-Dunlop N, Le Bouar G, Massardier J, Roditis L, Rosenblatt J, Sartor A, Thong-Vanh C, Lelong N, Khoshnood B; , for the MALFPULM study group; members of the MALFPULM study group:. Delacourt C, et al. Eur Respir J. 2022 Feb 3;59(2):2100949. doi: 10.1183/13993003.00949-2021. Print 2022 Feb. Eur Respir J. 2022. PMID: 34266941 Free article.
OBJECTIVES: Most children with prenatally diagnosed congenital pulmonary malformations (CPMs) are asymptomatic at birth. We aimed to develop a parsimonious prognostic model for predicting the risk of neonatal respiratory distress (NRD) in preterm and term infants wi …
OBJECTIVES: Most children with prenatally diagnosed congenital pulmonary malformations (CPMs) are asymptomatic at birth. We aimed to …
Rapid Improvement after Starting Elexacaftor-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and Advanced Pulmonary Disease.
Burgel PR, Durieu I, Chiron R, Ramel S, Danner-Boucher I, Prevotat A, Grenet D, Marguet C, Reynaud-Gaubert M, Macey J, Mely L, Fanton A, Quetant S, Lemonnier L, Paillasseur JL, Da Silva J, Martin C; French Cystic Fibrosis Reference Network Study Group. Burgel PR, et al. Am J Respir Crit Care Med. 2021 Jul 1;204(1):64-73. doi: 10.1164/rccm.202011-4153OC. Am J Respir Crit Care Med. 2021. PMID: 33600738

The mean (95% confidence interval) absolute increase in the ppFEV(1) was +15.1 (+13.8 to +16.4; P < 0.0001), and the mean (95% confidence interval) in weight was +4.2 kg (+3.9 to +4.6; P < 0.0001). The number of patients requiring long-term oxygen, noninvasive ventil

…

The mean (95% confidence interval) absolute increase in the ppFEV(1) was +15.1 (+13.8 to +16.4; P < 0.0001), and the mean (95% confidence

…
Child-Adult Transition in Sarcoidosis: A Series of 52 Patients.
Chauveau S, Jeny F, Montagne ME, Taam RA, Houdouin V, Meinzer U, Delacourt C, Epaud R, Aubart FC, Chapelon-Abric C, Israël-Biet D, Juvin K, Dossier A, Bodaghi B, Prévot G, Naccache JM, Mattioni S, Deschildre A, Brouard J, Tazi A, Meckenstock R, Didier M, Haroche J, Clement A, Bernaudin JF, Nunes H, Valeyre D, Nathan N, Gsf FTFSG. Chauveau S, et al. Among authors: deschildre a. J Clin Med. 2020 Jul 3;9(7):2097. doi: 10.3390/jcm9072097. J Clin Med. 2020. PMID: 32635292 Free PMC article.
Patients received a high corticosteroid cumulative dose (median 17,900 mg) for a median duration of five years (range 0-32), resulting in mostly mild (18; 35.3%) and rarely severe (2; 3.8%) adverse events. (4) Conclusions: Pediatric-onset sarcoidosis needed a long-term tre …
Patients received a high corticosteroid cumulative dose (median 17,900 mg) for a median duration of five years (range 0-32), resulting in mo …
Childhood asthma heterogeneity at the era of precision medicine: Modulating the immune response or the microbiota for the management of asthma attack.
Lejeune S, Deschildre A, Le Rouzic O, Engelmann I, Dessein R, Pichavant M, Gosset P. Lejeune S, et al. Among authors: deschildre a. Biochem Pharmacol. 2020 Sep;179:114046. doi: 10.1016/j.bcp.2020.114046. Epub 2020 May 22. Biochem Pharmacol. 2020. PMID: 32446884 Free PMC article. Review.
These dynamic interactions may impact the presentations of asthma attacks, and have long-term consequences. The aim of this review is to synthesize studies exploring immune mechanisms impairment against viruses and bacteria promoting asthma attacks in children. ...
These dynamic interactions may impact the presentations of asthma attacks, and have long-term consequences. The aim of this review is …
Health-related quality of life in infants and children with interstitial lung disease.
Lauby C, Boelle PY, Abou Taam R, Bessaci K, Brouard J, Dalphin ML, Delacourt C, Delestrain C, Deschildre A, Dubus JC, Fayon M, Giovannini-Chami L, Houdouin V, Houzel A, Marguet C, Pin I, Reix P, Renoux MC, Schweitzer C, Tatopoulos A, Thumerelle C, Troussier F, Wanin S, Weiss L, Clement A, Epaud R, Nathan N. Lauby C, et al. Among authors: deschildre a. Pediatr Pulmonol. 2019 Jun;54(6):828-836. doi: 10.1002/ppul.24308. Epub 2019 Mar 13. Pediatr Pulmonol. 2019. PMID: 30868755
The clinical factors associated with a lower total score were: extrapulmonary expression of the disease, higher Fan severity score, long-term oxygen therapy, nutritional support, and a number of oral treatments. ...
The clinical factors associated with a lower total score were: extrapulmonary expression of the disease, higher Fan severity score, long- …
New perspectives of childhood asthma treatment with biologics.
Just J, Deschildre A, Lejeune S, Amat F. Just J, et al. Among authors: deschildre a. Pediatr Allergy Immunol. 2019 Mar;30(2):159-171. doi: 10.1111/pai.13007. Epub 2018 Dec 16. Pediatr Allergy Immunol. 2019. PMID: 30444939 Review.
Pediatric specificities have to be addressed and validated by studies in children. Long-term effectiveness and particularly the impact on the natural history of asthma should also be investigated. ...
Pediatric specificities have to be addressed and validated by studies in children. Long-term effectiveness and particularly the impac …
Bronchial Foreign Body Alerting of a Bronchial Tumor: The Need of a Follow-Up Radiography.
El-Rifai N, Shahine S, Sidani H, Sabeh Aion A, Deschildre A, Copin MC. El-Rifai N, et al. Among authors: deschildre a. Case Rep Pediatr. 2016;2016:6714351. doi: 10.1155/2016/6714351. Epub 2016 Nov 22. Case Rep Pediatr. 2016. PMID: 27994904 Free PMC article.
The presence of MAML2 rearrangement confers a favorable outcome and may have long-term implications for the clinical management....
The presence of MAML2 rearrangement confers a favorable outcome and may have long-term implications for the clinical management....
[Inhaled corticosteroids and growth: should we be worried?].
Pouessel G, Gueorguieva I, Bernaczyk Y, Flammarion S, Thumerelle C, Deschildre A. Pouessel G, et al. Among authors: deschildre a. Arch Pediatr. 2015 Aug;22(8):886-91. doi: 10.1016/j.arcped.2015.05.008. Epub 2015 Jul 2. Arch Pediatr. 2015. PMID: 26142772 French.
The objective of this study was to synthesize data on the potential effects of ICSs on growth in children. Studies on the short-term impact of ICSs on growth evaluated by knemometry cannot be extrapolated to the medium or long term and therefore have no utility in r …
The objective of this study was to synthesize data on the potential effects of ICSs on growth in children. Studies on the short-term …
22 results