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Continuous secretion of monocyte chemotactic factors and fibroblast growth factors by alveolar macrophages following a single exposure to bleomycin in vitro.
Denholm EM. Denholm EM. Am J Pathol. 1992 Oct;141(4):965-71. Am J Pathol. 1992. PMID: 1384342 Free PMC article.
The data suggest that a similar direct activation of macrophages by bleomycin may promote the long-term production of these factors in vivo, resulting in continued monocyte recruitment and promotion of fibroblast proliferation in fibrotic lungs....
The data suggest that a similar direct activation of macrophages by bleomycin may promote the long-term production of these factors i …