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Risk of stroke within 3, 7, 14, 21 and 30 days after influenza vaccination in Alberta, Canada: A population-based study.
Tanaka K, Demchuk AM, Malo S, Hill MD, Holodinsky JK. Tanaka K, et al. Among authors: demchuk am. Eur J Neurol. 2024 Apr;31(4):e16172. doi: 10.1111/ene.16172. Epub 2023 Dec 20. Eur J Neurol. 2024. PMID: 38117538
BACKGROUND AND PURPOSE: Influenza vaccination is associated with a longer-term protective effect against stroke; however, it has a short-term inflammatory response which may increase short-term risk of stroke. The aim was to investigate the association betwee …
BACKGROUND AND PURPOSE: Influenza vaccination is associated with a longer-term protective effect against stroke; however, it has a sh …
Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy.
Halliday A, Bulbulia R, Bonati LH, Chester J, Cradduck-Bamford A, Peto R, Pan H; ACST-2 Collaborative Group. Halliday A, et al. Lancet. 2021 Sep 18;398(10305):1065-1073. doi: 10.1016/S0140-6736(21)01910-3. Epub 2021 Aug 29. Lancet. 2021. PMID: 34469763 Free PMC article. Clinical Trial.
Comparison of their long-term protective effects requires large-scale randomised evidence. ...INTERPRETATION: Serious complications are similarly uncommon after competent CAS and CEA, and the long-term effects of these two carotid artery procedures on fatal or disab …
Comparison of their long-term protective effects requires large-scale randomised evidence. ...INTERPRETATION: Serious complications a …
Return on Investment in Endovascular Care: The Case of Endovascular Reperfusion Alberta.
Thanh NX, Jeerakathil T, Stang J, Halabi ML, Mann B, Buck BH, Rempel JL, Goyal M, Demchuk AM, Valaire S, Wasylak T, Hill MD. Thanh NX, et al. Among authors: demchuk am. Can J Neurol Sci. 2022 Sep;49(5):629-635. doi: 10.1017/cjn.2021.189. Epub 2021 Aug 6. Can J Neurol Sci. 2022. PMID: 34353400
Probabilities of ERA being cost saving were 39% (31%), 97% (96%), and 94% (91%), for short, medium, and long-term time horizons, respectively. CONCLUSION: The ERA program was cost saving in the medium and long-term time horizons. Results emphasized the importance of …
Probabilities of ERA being cost saving were 39% (31%), 97% (96%), and 94% (91%), for short, medium, and long-term time horizons, resp …
Endovascular Treatment Effect Diminishes With Increasing Thrombus Perviousness: Pooled Data From 7 Trials on Acute Ischemic Stroke.
Kappelhof M, Tolhuisen ML, Treurniet KM, Dutra BG, Alves H, Zhang G, Brown S, Muir KW, Dávalos A, Roos YBWEM, Saver JL, Demchuk AM, Jovin TG, Bracard S, Campbell BCV, van der Lugt A, Guillemin F, White P, Hill MD, Dippel DWJ, Mitchell PJ, Goyal M, Marquering HA, Majoie CBLM; HERMES Collaborators. Kappelhof M, et al. Among authors: demchuk am. Stroke. 2021 Nov;52(11):3633-3641. doi: 10.1161/STROKEAHA.120.033124. Epub 2021 Jul 20. Stroke. 2021. PMID: 34281377 Free PMC article.
RESULTS: Increased perviousness was associated with improved functional outcome. After adding a multiplicative term of thrombus attenuation increase and treatment allocation, model fit improved significantly (P=0.03), indicating interaction between perviousness and EVT ben …
RESULTS: Increased perviousness was associated with improved functional outcome. After adding a multiplicative term of thrombus atten …
Thrombolysis outcomes according to arterial characteristics of acute ischemic stroke by alteplase dose and blood pressure target.
Zhou Z, Xia C, Mair G, Delcourt C, Yoshimura S, Liu X, Chen Z, Malavera A, Carcel C, Chen X, Wang X, Al-Shahi Salman R, Robinson TG, Lindley RI, Chalmers J, Wardlaw JM, Parsons MW, Demchuk AM, Anderson CS. Zhou Z, et al. Among authors: demchuk am. Int J Stroke. 2022 Jun;17(5):566-575. doi: 10.1177/17474930211025436. Epub 2021 Jun 24. Int J Stroke. 2022. PMID: 34096413 Clinical Trial.
Heterogeneity in associations for outcomes across subgroups was estimated by adding an interaction term to the models. RESULTS: There were 940 participants: 607 in alteplase arm only, 243 in blood pressure arm only, and 90 assigned to both arms. ...
Heterogeneity in associations for outcomes across subgroups was estimated by adding an interaction term to the models. RESULTS: There …
Prediction of Clinical Outcomes in Acute Ischaemic Stroke Patients: A Comparative Study.
Rajashekar D, Hill MD, Demchuk AM, Goyal M, Fiehler J, Forkert ND. Rajashekar D, et al. Among authors: demchuk am. Front Neurol. 2021 May 6;12:663899. doi: 10.3389/fneur.2021.663899. eCollection 2021. Front Neurol. 2021. PMID: 34025567 Free PMC article.
However, most previously described methods for predicting long-term stroke outcomes do not make use of the full multi-modal data available. ...
However, most previously described methods for predicting long-term stroke outcomes do not make use of the full multi-modal data avai …
Calculation of Prognostic Scores, Using Delayed Imaging, Outperforms Baseline Assessments in Acute Intracerebral Hemorrhage.
Lun R, Yogendrakumar V, Demchuk AM, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Y, Dzialowski I, Kobayashi A, Boulanger JM, Gubitz G, Srivastava P, Roy J, Kase CS, Bhatia R, Hill MD, Dowlatshahi D. Lun R, et al. Among authors: demchuk am. Stroke. 2020 Apr;51(4):1107-1110. doi: 10.1161/STROKEAHA.119.027119. Epub 2020 Mar 10. Stroke. 2020. PMID: 32151235
We propose that calculation of prognostic scores using delayed imaging will have better predictive values for long-term mortality compared with baseline assessments. Methods- We analyzed prospectively collected data from the multicenter PREDICT study (Prediction of Hematom …
We propose that calculation of prognostic scores using delayed imaging will have better predictive values for long-term mortality com …
Public Health and Cost Benefits of Successful Reperfusion After Thrombectomy for Stroke.
Kunz WG, Almekhlafi MA, Menon BK, Saver JL, Hunink MG, Dippel DWJ, Majoie CBLM, Liebeskind DS, Jovin TG, Davalos A, Bracard S, Guillemin F, Campbell BCV, Mitchell PJ, White P, Muir KW, Brown S, Demchuk AM, Hill MD, Goyal M; HERMES Collaborators. Kunz WG, et al. Among authors: demchuk am. Stroke. 2020 Mar;51(3):899-907. doi: 10.1161/STROKEAHA.119.027874. Epub 2020 Jan 22. Stroke. 2020. PMID: 31964289
Conclusions- Improved reperfusion grants patients with stroke additional QALYs and leads to long-term cost savings. Procedural strategies to achieve complete reperfusion should be assessed for safety and feasibility, even when initial reperfusion seems to be adequate....
Conclusions- Improved reperfusion grants patients with stroke additional QALYs and leads to long-term cost savings. Procedural strate …
New and expanding ventricular hemorrhage predicts poor outcome in acute intracerebral hemorrhage.
Yogendrakumar V, Ramsay T, Fergusson D, Demchuk AM, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Y, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz G, Srivastava P, Roy J, Kase CS, Bhatia R, Hill MD, Warren AD, Anderson CD, Gurol ME, Greenberg SM, Viswanathan A, Rosand J, Goldstein JN, Dowlatshahi D; the PREDICT/Sunnybrook CTA Study Group. Yogendrakumar V, et al. Among authors: demchuk am. Neurology. 2019 Aug 27;93(9):e879-e888. doi: 10.1212/WNL.0000000000008007. Epub 2019 Aug 1. Neurology. 2019. PMID: 31371565 Free PMC article.
OBJECTIVE: To describe the relationship between intraventricular hemorrhage (IVH) expansion and long-term outcome and to use this relationship to select and validate clinically relevant thresholds of IVH expansion in 2 separate intracerebral hemorrhage (ICH) populations. . …
OBJECTIVE: To describe the relationship between intraventricular hemorrhage (IVH) expansion and long-term outcome and to use this rel …
Observed Cost and Variations in Short Term Cost-Effectiveness of Therapy for Ischemic Stroke in Interventional Management of Stroke (IMS) III.
Simpson KN, Simpson AN, Mauldin PD, Palesch YY, Yeatts SD, Kleindorfer D, Tomsick TA, Foster LD, Demchuk AM, Khatri P, Hill MD, Jauch EC, Jovin TG, Yan B, von Kummer R, Molina CA, Goyal M, Schonewille WJ, Mazighi M, Engelter ST, Anderson C, Spilker J, Carrozzella J, Ryckborst KJ, Janis LS, Broderick JP; Interventional Management of Stroke (IMS) III Investigators. Simpson KN, et al. Among authors: demchuk am. J Am Heart Assoc. 2017 May 8;6(5):e004513. doi: 10.1161/JAHA.116.004513. J Am Heart Assoc. 2017. PMID: 28483774 Free PMC article. Clinical Trial.
The kind of resources used postdischarge also varied between treatment groups. Incremental short-term cost-effectiveness ratios varied greatly when treatments were compared for patient subgroups. ...
The kind of resources used postdischarge also varied between treatment groups. Incremental short-term cost-effectiveness ratios varie …
25 results