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Endurance training alleviates MCP-1 and TERRA accumulation at old age in human skeletal muscle.
Balan E, Diman A, Everard A, Nielens H, Decottignies A, Deldicque L. Balan E, et al. Among authors: deldicque l. Exp Gerontol. 2021 Oct 1;153:111510. doi: 10.1016/j.exger.2021.111510. Epub 2021 Aug 8. Exp Gerontol. 2021. PMID: 34371098
The effects of chronic endurance exercise and aging were tested in the blood and muscle of 34 male subjects divided into four groups: young (YU) or old (OU) untrained, young (YT) or old (OT) trained cyclists. Long-term endurance training limited the age-dependent elevation …
The effects of chronic endurance exercise and aging were tested in the blood and muscle of 34 male subjects divided into four groups: young …
Protein Intake and Exercise-Induced Skeletal Muscle Hypertrophy: An Update.
Deldicque L. Deldicque L. Nutrients. 2020 Jul 7;12(7):2023. doi: 10.3390/nu12072023. Nutrients. 2020. PMID: 32646013 Free PMC article.
Optimizing those conditions favor a positive net protein balance, which in the long term, may result in muscle mass accretion. Last but not least, it is also essential to take the nutritional status and the exercise training load into consideration when looking for mainten …
Optimizing those conditions favor a positive net protein balance, which in the long term, may result in muscle mass accretion. Last b …
Environmental hypoxia favors myoblast differentiation and fast phenotype but blunts activation of protein synthesis after resistance exercise in human skeletal muscle.
Gnimassou O, Fernández-Verdejo R, Brook M, Naslain D, Balan E, Sayda M, Cegielski J, Nielens H, Decottignies A, Demoulin JB, Smith K, Atherton PJ, Francaux M, Deldicque L. Gnimassou O, et al. Among authors: deldicque l. FASEB J. 2018 Oct;32(10):5272-5284. doi: 10.1096/fj.201800049RR. Epub 2018 Apr 19. FASEB J. 2018. PMID: 29672220
Contrary to our hypothesis, environmental hypoxia did not potentiate the short-term anabolic response after resistance exercise, but it initiated transcriptional regulations that could potentially translate into satellite cell incorporation and higher force production in t …
Contrary to our hypothesis, environmental hypoxia did not potentiate the short-term anabolic response after resistance exercise, but …
Repeated maximal-intensity hypoxic exercise superimposed to hypoxic residence boosts skeletal muscle transcriptional responses in elite team-sport athletes.
Brocherie F, Millet GP, D'Hulst G, Van Thienen R, Deldicque L, Girard O. Brocherie F, et al. Among authors: deldicque l. Acta Physiol (Oxf). 2018 Jan;222(1). doi: 10.1111/apha.12851. Epub 2017 Feb 22. Acta Physiol (Oxf). 2018. PMID: 28103427 Clinical Trial.
CONCLUSION: Combined with residence in normobaric hypoxia, repeated maximal-intensity hypoxic exercise induces short-term post-intervention beneficial changes in muscle transcriptional factors that are of larger magnitude (or not observed) than with similar normoxic exerci …
CONCLUSION: Combined with residence in normobaric hypoxia, repeated maximal-intensity hypoxic exercise induces short-term post-interv …
Effect of acute environmental hypoxia on protein metabolism in human skeletal muscle.
D'Hulst G, Jamart C, Van Thienen R, Hespel P, Francaux M, Deldicque L. D'Hulst G, et al. Among authors: deldicque l. Acta Physiol (Oxf). 2013 Jul;208(3):251-64. doi: 10.1111/apha.12086. Epub 2013 Mar 25. Acta Physiol (Oxf). 2013. PMID: 23418947 Free article. Clinical Trial.
CONCLUSION: Contrary to our hypothesis and despite an increase in the mRNA level of Redd1, an inhibitor of the mTORC1 pathway, short-term acute environmental hypoxia induced a higher response of PKB and S6K1 to a meal, which may be due to increased plasma insulin concentra …
CONCLUSION: Contrary to our hypothesis and despite an increase in the mRNA level of Redd1, an inhibitor of the mTORC1 pathway, short-term …
Role of alpha-actinin-3 in contractile properties of human single muscle fibers: a case series study in paraplegics.
Broos S, Malisoux L, Theisen D, Francaux M, Deldicque L, Thomis MA. Broos S, et al. Among authors: deldicque l. PLoS One. 2012;7(11):e49281. doi: 10.1371/journal.pone.0049281. Epub 2012 Nov 8. PLoS One. 2012. PMID: 23145141 Free PMC article.
The preservation of type I fibers and the absence of type II(x) fibers in the XX individual indicate a restricted transformation of the muscle fiber composition to type II fibers in response to long-term muscle disuse. Lack of alpha-actinin-3 may decrease unloaded shorteni …
The preservation of type I fibers and the absence of type II(x) fibers in the XX individual indicate a restricted transformation of the musc …
Hepatic steatosis in n-3 fatty acid depleted mice: focus on metabolic alterations related to tissue fatty acid composition.
Pachikian BD, Neyrinck AM, Cani PD, Portois L, Deldicque L, De Backer FC, Bindels LB, Sohet FM, Malaisse WJ, Francaux M, Carpentier YA, Delzenne NM. Pachikian BD, et al. Among authors: deldicque l. BMC Physiol. 2008 Dec 1;8:21. doi: 10.1186/1472-6793-8-21. BMC Physiol. 2008. PMID: 19046413 Free PMC article.
Steatosis occurs through a mechanism independent of the shift between beta-oxidation and lipogenesis. Moreover, long term n-3 PUFA depletion decreases the expression of factors involved in the unfolded protein response, suggesting a lower protection against endoplasmic ret …
Steatosis occurs through a mechanism independent of the shift between beta-oxidation and lipogenesis. Moreover, long term n-3 PUFA de …