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Merkel Cell Carcinoma in the HIV-1/AIDS Patient.
Goldstein RH, DeCaprio JA. Goldstein RH, et al. Among authors: decaprio ja. Cancer Treat Res. 2019;177:211-229. doi: 10.1007/978-3-030-03502-0_8. Cancer Treat Res. 2019. PMID: 30523626
For advanced, metastatic, and recurrent MCC, checkpoint blockade inhibitors targeting PD-1 and PD-L1 have shown remarkable activity including durable long-term. MCC in patients living with HIV-1/AIDS are treated with similar modalities as HIV-1 uninfected individuals with …
For advanced, metastatic, and recurrent MCC, checkpoint blockade inhibitors targeting PD-1 and PD-L1 have shown remarkable activity includin …
AMP-activated protein kinase is essential for survival in chronic hypoxia.
Borger DR, Gavrilescu LC, Bucur MC, Ivan M, Decaprio JA. Borger DR, et al. Among authors: decaprio ja. Biochem Biophys Res Commun. 2008 May 30;370(2):230-4. doi: 10.1016/j.bbrc.2008.03.056. Epub 2008 Mar 24. Biochem Biophys Res Commun. 2008. PMID: 18359290 Free PMC article.
This study was undertaken to interrogate cancer cell survival during long-term hypoxic stress. Two systems with relevance to carcinogenesis were employed: Fully transformed BJ cells and a renal carcinoma cell line (786-0). ...
This study was undertaken to interrogate cancer cell survival during long-term hypoxic stress. Two systems with relevance to carcinog …