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Development of beta 3-adrenoceptor agonists for the treatment of obesity and diabetes--an update.
Weyer C, Gautier JF, Danforth E Jr. Weyer C, et al. Among authors: danforth e jr. Diabetes Metab. 1999 Mar;25(1):11-21. Diabetes Metab. 1999. PMID: 10335419 Review.
These include the major question as to whether the number of biologically active beta 3-ARs in adult humans is sufficient to produce relevant metabolic effects and, if so, whether their long-term stimulation is safe and free of unwarranted side effects. In addition, the me …
These include the major question as to whether the number of biologically active beta 3-ARs in adult humans is sufficient to produce relevan …
Decreased thermic effect of a mixed meal during overnutrition in human obesity.
Katzeff HL, Danforth E Jr. Katzeff HL, et al. Among authors: danforth e jr. Am J Clin Nutr. 1989 Nov;50(5):915-21. doi: 10.1093/ajcn/50.5.915. Am J Clin Nutr. 1989. PMID: 2683718
Short-term mixed calorie overfeeding increases basal energy expenditure in man but its effects on the thermic effect of a meal (TEM) are unclear. ...
Short-term mixed calorie overfeeding increases basal energy expenditure in man but its effects on the thermic effect of a meal (TEM) …
Dietary-induced alterations in thyroid hormone metabolism during overnutrition.
Danforth E Jr, Horton ES, O'Connell M, Sims EA, Burger AG, Ingbar SH, Braverman L, Vagenakis AG. Danforth E Jr, et al. J Clin Invest. 1979 Nov;64(5):1336-47. doi: 10.1172/JCI109590. J Clin Invest. 1979. PMID: 500814 Free PMC article.
No change in the caloric requirement to maintain weight or concentrations of T3 was found after long-term (3 mo) fat overfeeding. In studies of short-term overfeeding (3 wk) the serum concentrations of T3 and its metabolic clearance were increased, resulting in a ma …
No change in the caloric requirement to maintain weight or concentrations of T3 was found after long-term (3 mo) fat overfeeding. In …