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Year Number of Results
1998 1
1999 2
2006 1
2008 1
2010 1
2012 1
2013 1
2014 1
2015 2
2016 1
2017 5
2018 4
2019 8
2020 4
2021 4
2022 6
2023 2
2024 0

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43 results

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Page 1
Development and characterization of ferret ex vivo tracheal injury and cell engraftment model.
Ievlev V, Pai AC, Dillon DS Jr, Kuhl S, Lynch TJ, Freischlag KW, Gries CB, Engelhardt JF, Parekh KR. Ievlev V, et al. Front Med (Lausanne). 2023 Apr 11;10:1144754. doi: 10.3389/fmed.2023.1144754. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37113613 Free PMC article.
Injured explants can be cultured at ALI (using the novel tissue-transwell device on the right) and submerged long-term to evaluate tissue-autonomous regeneration responses. 4. Tracheal explants can also be used for low throughput screens of compounds to improve cell engraf …
Injured explants can be cultured at ALI (using the novel tissue-transwell device on the right) and submerged long-term to evaluate ti …
The impact of elexacaftor/tezacaftor/ivacaftor on body composition in a small cohort of youth with cystic fibrosis.
Granados A, Chan CL, Moheet A, Vigers T, Arbeláez AM, Larson Ode K. Granados A, et al. Pediatr Pulmonol. 2023 Jun;58(6):1805-1811. doi: 10.1002/ppul.26388. Epub 2023 Mar 17. Pediatr Pulmonol. 2023. PMID: 36929859
Both insulin secretion and insulin resistance increased. Longer-term metabolic consequences of ETI need further investigation....
Both insulin secretion and insulin resistance increased. Longer-term metabolic consequences of ETI need further investigation....
Robust Measures of Image-Registration-Derived Lung Biomechanics in SPIROMICS.
Pan Y, Wang D, Chaudhary MFA, Shao W, Gerard SE, Durumeric OC, Bhatt SP, Barr RG, Hoffman EA, Reinhardt JM, Christensen GE. Pan Y, et al. J Imaging. 2022 Nov 16;8(11):309. doi: 10.3390/jimaging8110309. J Imaging. 2022. PMID: 36422058 Free PMC article.
Chronic obstructive pulmonary disease (COPD) is an umbrella term used to define a collection of inflammatory lung diseases that cause airflow obstruction and severe damage to the lung parenchyma. ...
Chronic obstructive pulmonary disease (COPD) is an umbrella term used to define a collection of inflammatory lung diseases that cause …
Pseudomonas aeruginosa Can Diversify after Host Cell Invasion to Establish Multiple Intracellular Niches.
Kumar NG, Nieto V, Kroken AR, Jedel E, Grosser MR, Hallsten ME, Mettrucio MME, Yahr TL, Evans DJ, Fleiszig SMJ. Kumar NG, et al. mBio. 2022 Dec 20;13(6):e0274222. doi: 10.1128/mbio.02742-22. Epub 2022 Nov 14. mBio. 2022. PMID: 36374039 Free PMC article.
., rapid replication versus slow replication/persistence) suggest cooperation favoring both short- and long-term interests and another potential pathway to treatment failure. ...
., rapid replication versus slow replication/persistence) suggest cooperation favoring both short- and long-term interests and anothe …
Ferret Lung Transplantation Models Differential Lymphoid Aggregate Morphology Between Restrictive and Obstructive Forms of Chronic Lung Allograft Dysfunction.
Lynch TJ, Ahlers BA, Swatek AM, Ievlev V, Pai AC, Brooks L, Tang Y, Evans IA, Meyerholz DK, Engelhardt JF, Parekh KR. Lynch TJ, et al. Transplantation. 2022 Oct 1;106(10):1974-1989. doi: 10.1097/TP.0000000000004148. Epub 2022 Apr 15. Transplantation. 2022. PMID: 35442232 Free PMC article.
BACKGROUND: Long-term survival after lung transplantation remains limited by chronic lung allograft dysfunction (CLAD). ...
BACKGROUND: Long-term survival after lung transplantation remains limited by chronic lung allograft dysfunction (CLAD). ...
Quantitative Chest CT Assessment of Small Airways Disease in Post-Acute SARS-CoV-2 Infection.
Cho JL, Villacreses R, Nagpal P, Guo J, Pezzulo AA, Thurman AL, Hamzeh NY, Blount RJ, Fortis S, Hoffman EA, Zabner J, Comellas AP. Cho JL, et al. Radiology. 2022 Jul;304(1):185-192. doi: 10.1148/radiol.212170. Epub 2022 Mar 15. Radiology. 2022. PMID: 35289657 Free PMC article.
Background The long-term effects of SARS-CoV-2 infection on pulmonary structure and function remain incompletely characterized. ...Conclusion In survivors of COVID-19, small airways disease occurred independently of initial infection severity. The long-term conseque …
Background The long-term effects of SARS-CoV-2 infection on pulmonary structure and function remain incompletely characterized. ...Co …
The Role of Surgical Management in Chronic Pancreatitis in Children: A Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee.
Nathan JD, Ellery K, Balakrishnan K, Bhatt H, Ganoza A, Husain SZ, Kumar R, Morinville VD, Quiros JA, Schwarzenberg SJ, Sellers ZM, Uc A, Abu-El-Haija M. Nathan JD, et al. J Pediatr Gastroenterol Nutr. 2022 May 1;74(5):706-719. doi: 10.1097/MPG.0000000000003439. Epub 2022 Mar 3. J Pediatr Gastroenterol Nutr. 2022. PMID: 35258494 Free PMC article. Review.
A multidisciplinary team approach is needed to assure that the best possible operation is selected for each patient, their recovery is optimized, and their immediate and long-term postoperative needs are well-met....
A multidisciplinary team approach is needed to assure that the best possible operation is selected for each patient, their recovery is optim …
Development of human alveolar epithelial cell models to study distal lung biology and disease.
Tran E, Shi T, Li X, Chowdhury AY, Jiang D, Liu Y, Wang H, Yan C, Wallace WD, Lu R, Ryan AL, Marconett CN, Zhou B, Borok Z, Offringa IA. Tran E, et al. iScience. 2022 Jan 15;25(2):103780. doi: 10.1016/j.isci.2022.103780. eCollection 2022 Feb 18. iScience. 2022. PMID: 35169685 Free PMC article.
Our approach yields lung progenitor lines that retain the ability to differentiate along the alveolar cell lineage despite long-term expansion and provides a valuable system to model and study the distal lung in vitro....
Our approach yields lung progenitor lines that retain the ability to differentiate along the alveolar cell lineage despite long-term …
Polycythemia is Associated with Lower Incidence of Severe COPD Exacerbations in the SPIROMICS Study.
Fawzy A, Woo H, Balasubramanian A, Barjaktarevic I, Barr RG, Bowler RP, Comellas AP, Cooper CB, Couper D, Criner GJ, Dransfield MT, Han MK, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, McCormack M, Paine Iii R, Peters S, Wise R, Woodruff PG, Hansel NN, Putcha N. Fawzy A, et al. Chronic Obstr Pulm Dis. 2021 Jul 28;8(3):326-335. doi: 10.15326/jcopdf.2021.0216. Chronic Obstr Pulm Dis. 2021. PMID: 34197703 Free PMC article.
Secondary polycythemia has long been recognized as a consequence of chronic pulmonary disease and hypoxemia and is associated with lower mortality and fewer hospitalizations among individuals with chronic obstructive pulmonary disease (COPD)-prescribed long-term oxygen the …
Secondary polycythemia has long been recognized as a consequence of chronic pulmonary disease and hypoxemia and is associated with lower mor …
Lef-1 controls cell cycle progression in airway basal cells to regulate proliferation and differentiation.
Jensen-Cody CW, Crooke AK, Rotti PG, Ievlev V, Shahin W, Park SY, Lynch TJ, Engelhardt JF. Jensen-Cody CW, et al. Stem Cells. 2021 Sep;39(9):1221-1235. doi: 10.1002/stem.3386. Epub 2021 May 14. Stem Cells. 2021. PMID: 33932322 Free PMC article.
We demonstrate that conditional deletion of Lef-1 stalls basal cell proliferation at the G1/S transition of the cell cycle, and that Lef-1 knockout cells are unable to maintain luminal tracheal cell types in long-term air-liquid interface culture. RNA sequencing analysis r …
We demonstrate that conditional deletion of Lef-1 stalls basal cell proliferation at the G1/S transition of the cell cycle, and that Lef-1 k …
43 results