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Increased brain transport and metabolism of acetate in hypoglycemia unawareness.
Gulanski BI, De Feyter HM, Page KA, Belfort-DeAguiar R, Mason GF, Rothman DL, Sherwin RS. Gulanski BI, et al. J Clin Endocrinol Metab. 2013 Sep;98(9):3811-20. doi: 10.1210/jc.2013-1701. Epub 2013 Jun 24. J Clin Endocrinol Metab. 2013. PMID: 23796565 Free PMC article.
CONTEXT: Intensive insulin therapy reduces the risk for long-term complications in patients with type 1 diabetes mellitus (T1DM) but increases the risk for hypoglycemia-associated autonomic failure (HAAF), a syndrome that includes hypoglycemia unawareness and defective glu …
CONTEXT: Intensive insulin therapy reduces the risk for long-term complications in patients with type 1 diabetes mellitus (T1DM) but …
Temporal changes in insulin resistance and secretion in 24-h-fasted conscious pregnant rats.
Rossi G, Sherwin RS, Penzias AS, Lapaczewski P, Jacob RJ, Shulman GI, Diamond MP. Rossi G, et al. Am J Physiol. 1993 Dec;265(6 Pt 1):E845-51. doi: 10.1152/ajpendo.1993.265.6.E845. Am J Physiol. 1993. PMID: 8279539
We conclude that rat pregnancy is characterized by the early appearance of peripheral insulin resistance. As pregnancy progresses toward term, marked hepatic insulin resistance and insulin hypersecretion develop, whereas peripheral insulin resistance demonstrates negligibl …
We conclude that rat pregnancy is characterized by the early appearance of peripheral insulin resistance. As pregnancy progresses toward …
Inhibitory effect of pregnancy on counterregulatory hormone responses to hypoglycemia in awake rat.
Rossi G, Lapaczewski P, Diamond MP, Jacob RJ, Shulman GI, Sherwin RS. Rossi G, et al. Diabetes. 1993 Oct;42(10):1440-5. doi: 10.2337/diab.42.10.1440. Diabetes. 1993. PMID: 8375583
To investigate whether pregnancy may contribute as an independent hypoglycemia risk factor, awake pregnant rats that were near term underwent stepped insulin hypoglycemic (3.4 and 2.3 mM) clamp studies in the fasted and nonfasted states. ...
To investigate whether pregnancy may contribute as an independent hypoglycemia risk factor, awake pregnant rats that were near term u …