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Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial.
Huang AJ, Cummings SR, Ganz P, Schembri M, Raghunathan H, Vittinghoff E, Gibson CJ, Grady D. Huang AJ, et al. Among authors: cummings sr. JAMA Intern Med. 2023 Aug 1;183(8):776-783. doi: 10.1001/jamainternmed.2023.1977. JAMA Intern Med. 2023. PMID: 37273224 Clinical Trial.
IMPORTANCE: Due to the potential risks of long-term systemic estrogen therapy, many menopausal women are interested in nonhormonal treatments for vasomotor symptoms. ...
IMPORTANCE: Due to the potential risks of long-term systemic estrogen therapy, many menopausal women are interested in nonhormonal tr …
Association of early-life famine exposure with low bone mass in adulthood.
Qi W, Cui L, Yin X, Yu W, Zhao N, Chen L, Tang S, Lin H, Cui L, Jin X, Xie Z, Jiang N, Cummings SR, Li Z, Wang L, Xia W. Qi W, et al. Among authors: cummings sr. Arch Osteoporos. 2023 Feb 14;18(1):32. doi: 10.1007/s11657-022-01209-3. Arch Osteoporos. 2023. PMID: 36786951
Famine exposure in early life has been found to have a long-term effect on metabolic diseases, but its effect on bone health was not clear. ...METHODS: We enrolled participants born in 1943-1962 from the China Osteoporosis Prevalence Study (COPS), which were classified int …
Famine exposure in early life has been found to have a long-term effect on metabolic diseases, but its effect on bone health was not …
Multiple Vertebral Fractures After Denosumab Discontinuation: FREEDOM and FREEDOM Extension Trials Additional Post Hoc Analyses.
Cosman F, Huang S, McDermott M, Cummings SR. Cosman F, et al. Among authors: cummings sr. J Bone Miner Res. 2022 Nov;37(11):2112-2120. doi: 10.1002/jbmr.4705. Epub 2022 Oct 12. J Bone Miner Res. 2022. PMID: 36088628 Free PMC article. Clinical Trial.
The DMAb discontinuation group was subsequently dichotomized by treatment duration: short-term (3 years; n = 262) and long-term (>3 years; n = 213) treatment. For any VF, exposure-adjusted annualized rates per 100 patient-years (95% confidence interval [CI]) were …
The DMAb discontinuation group was subsequently dichotomized by treatment duration: short-term (3 years; n = 262) and long-term …
Deep Learning With Electronic Health Records for Short-Term Fracture Risk Identification: Crystal Bone Algorithm Development and Validation.
Almog YA, Rai A, Zhang P, Moulaison A, Powell R, Mishra A, Weinberg K, Hamilton C, Oates M, McCloskey E, Cummings SR. Almog YA, et al. Among authors: cummings sr. J Med Internet Res. 2020 Oct 16;22(10):e22550. doi: 10.2196/22550. J Med Internet Res. 2020. PMID: 32956069 Free PMC article.
Common fracture risk assessment tools utilize a subset of clinical risk factors for prediction, and often require manual data entry. Furthermore, these tools predict risk over the long term and do not explicitly provide short-term risk estimates necessary to identif …
Common fracture risk assessment tools utilize a subset of clinical risk factors for prediction, and often require manual data entry. Further …
Walking Speed and Muscle Mass Estimated by the D3-Creatine Dilution Method Are Important Components of Sarcopenia Associated With Incident Mobility Disability in Older Men: A Classification and Regression Tree Analysis.
Zanker J, Patel S, Blackwell T, Duchowny K, Brennan-Olsen S, Cummings SR, Evans WJ, Orwoll ES, Scott D, Vogrin S, Cauley JA, Duque G, Cawthon PM; Osteoporotic Fractures in Men (MrOS) Study Group. Zanker J, et al. Among authors: cummings sr. J Am Med Dir Assoc. 2020 Dec;21(12):1997-2002.e1. doi: 10.1016/j.jamda.2020.03.017. Epub 2020 May 4. J Am Med Dir Assoc. 2020. PMID: 32381425 Free PMC article.
Muscle mass by D(3)Cr may be a key tool for predicting the risk of negative outcomes in older adults in the future, particularly in post-acute and long-term care settings....
Muscle mass by D(3)Cr may be a key tool for predicting the risk of negative outcomes in older adults in the future, particularly in post-acu …
Denosumab in postmenopausal women with osteoporosis and diabetes: Subgroup analysis of FREEDOM and FREEDOM extension.
Ferrari S, Eastell R, Napoli N, Schwartz A, Hofbauer LC, Chines A, Wang A, Pannacciulli N, Cummings SR. Ferrari S, et al. Among authors: cummings sr. Bone. 2020 May;134:115268. doi: 10.1016/j.bone.2020.115268. Epub 2020 Feb 10. Bone. 2020. PMID: 32058020 Free article. Clinical Trial.
Among those, BMD increased significantly with denosumab versus placebo in FREEDOM, and continued to increase during the Extension in long-term (continuing denosumab) and crossover (placebo to denosumab) denosumab subjects. ...During the first 3 years in FREEDOM Extension, …
Among those, BMD increased significantly with denosumab versus placebo in FREEDOM, and continued to increase during the Extension in long- …
Dysmobility Syndrome Independently Increases Fracture Risk in the Osteoporotic Fractures in Men (MrOS) Prospective Cohort Study.
Buehring B, Hansen KE, Lewis BL, Cummings SR, Lane NE, Binkley N, Ensrud KE, Cawthon PM; Osteoporotic Fractures in Men (MrOS) Study Research Group. Buehring B, et al. Among authors: cummings sr. J Bone Miner Res. 2018 Sep;33(9):1622-1629. doi: 10.1002/jbmr.3455. Epub 2018 Jun 21. J Bone Miner Res. 2018. PMID: 29701911 Free PMC article.
We proposed the term "dysmobility syndrome" (DS) to identify individuals with impaired musculoskeletal health, a risk factor for falls and fractures. ...
We proposed the term "dysmobility syndrome" (DS) to identify individuals with impaired musculoskeletal health, a risk factor for fall …
High-throughput serum proteomics for the identification of protein biomarkers of mortality in older men.
Orwoll ES, Wiedrick J, Jacobs J, Baker ES, Piehowski P, Petyuk V, Gao Y, Shi T, Smith RD, Bauer DC, Cummings SR, Nielson CM, Lapidus J; Osteoporotic Fractures in Men Study (MrOS) Research Group. Orwoll ES, et al. Among authors: cummings sr. Aging Cell. 2018 Apr;17(2):e12717. doi: 10.1111/acel.12717. Epub 2018 Feb 5. Aging Cell. 2018. PMID: 29399943 Free PMC article.
Overall, these results suggest that complex inflammatory pathways, and proteins in other pathways, are linked to 5-year mortality risk. This work may serve to identify novel biomarkers for near-term mortality....
Overall, these results suggest that complex inflammatory pathways, and proteins in other pathways, are linked to 5-year mortality risk. This …
The Ability of a Single BMD and Fracture History Assessment to Predict Fracture Over 25 Years in Postmenopausal Women: The Study of Osteoporotic Fractures.
Black DM, Cauley JA, Wagman R, Ensrud K, Fink HA, Hillier TA, Lui LY, Cummings SR, Schousboe JT, Napoli N. Black DM, et al. Among authors: cummings sr. J Bone Miner Res. 2018 Mar;33(3):389-395. doi: 10.1002/jbmr.3194. Epub 2017 Jul 18. J Bone Miner Res. 2018. PMID: 28719727 Free PMC article.
The ability of bone mineral density (BMD) and other risk factors to predict fracture risk is well-established for as long as 5 to 10 years. However, their value to predict risk over a longer term has not been directly studied. We investigated whether a single assessment of …
The ability of bone mineral density (BMD) and other risk factors to predict fracture risk is well-established for as long as 5 to 10 years. …
48 results