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Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS.
Lambrakis K, Papendick C, French JK, Quinn S, Blyth A, Seshadri A, Edmonds MJR, Chuang A, Khan E, Nelson AJ, Wright D, Horsfall M, Morton E, Karnon J, Briffa T, Cullen LA, Chew DP. Lambrakis K, et al. Among authors: cullen la. Circulation. 2021 Jul 13;144(2):113-125. doi: 10.1161/CIRCULATIONAHA.121.055009. Epub 2021 May 16. Circulation. 2021. PMID: 33998255 Clinical Trial.
Few direct comparisons have examined whether the enhanced performance of these assays at low concentrations leads to changes in care that improves longer-term outcomes. This study evaluated late outcomes of participants managed under an unmasked 0/1-hour high-sensitivity c …
Few direct comparisons have examined whether the enhanced performance of these assays at low concentrations leads to changes in care that im …
A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT).
Chew DP, Lambrakis K, Blyth A, Seshadri A, Edmonds MJR, Briffa T, Cullen LA, Quinn S, Karnon J, Chuang A, Nelson AJ, Wright D, Horsfall M, Morton E, French JK, Papendick C. Chew DP, et al. Among authors: cullen la. Circulation. 2019 Nov 5;140(19):1543-1556. doi: 10.1161/CIRCULATIONAHA.119.042891. Epub 2019 Sep 3. Circulation. 2019. PMID: 31478763 Clinical Trial.
CONCLUSIONS: This in-practice evaluation of a 0/1-hour hs-cTnT protocol embedded in ED care enabled more rapid discharge of patients with suspected acute coronary syndrome. Improving short-term outcomes among patients with newly recognized troponin T elevation will require …
CONCLUSIONS: This in-practice evaluation of a 0/1-hour hs-cTnT protocol embedded in ED care enabled more rapid discharge of patients with su …
Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.
Neumann JT, Twerenbold R, Ojeda F, Sörensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S; COMPASS-MI Study Group. Neumann JT, et al. Among authors: cullen la. N Engl J Med. 2019 Jun 27;380(26):2529-2540. doi: 10.1056/NEJMoa1803377. N Engl J Med. 2019. PMID: 31242362
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lower likelihood of myocardial infarction and a lower short-term risk of cardiovascular events. For example, high-sensitivity troponin …
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lo …