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Antenatal screening for thyroid dysfunction: pre-term birth, low birth-weight, and growth restriction.
Dhaifalah I, Havalova J, Langova D, Cuckle H. Dhaifalah I, et al. Among authors: cuckle h. J Matern Fetal Neonatal Med. 2024 Dec;37(1):2300416. doi: 10.1080/14767058.2023.2300416. Epub 2024 Jan 8. J Matern Fetal Neonatal Med. 2024. PMID: 38191240 Free article.
OBJECTIVE: To assess pre-term birth, low birth-weight and growth restriction according to maternal thyroid screening results and subsequent treatment. ...All cases and controls had information on gestation at delivery or birth-weight. Outcome measures …
OBJECTIVE: To assess pre-term birth, low birth-weight and growth restriction according to maternal thyroid screening re …
Modified multiple marker aneuploidy screening as a primary screening test for preeclampsia.
Huang T, Bedford HM, Rashid S, Rasasakaram E, Priston M, Mak-Tam E, Gibbons C, Meschino WS, Cuckle H, Mei-Dan E. Huang T, et al. Among authors: cuckle h. BMC Pregnancy Childbirth. 2022 Mar 8;22(1):190. doi: 10.1186/s12884-022-04514-4. BMC Pregnancy Childbirth. 2022. PMID: 35260099 Free PMC article.

Preterm and early-onset preeclampsia PE were defined as women with PE who delivered at < 37 and < 34 weeks of gestation, respectively. RESULTS: There were 147 pregnancies with PE (81 term, 49 preterm and 17 early-onset), 295 with gestational hypertension, and 166 pre

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Preterm and early-onset preeclampsia PE were defined as women with PE who delivered at < 37 and < 34 weeks of gestation, respectively.

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Early pregnancy prediction of spontaneous preterm birth before 32 completed weeks of pregnancy using plasma RNA: transcriptome discovery and initial validation of an RNA panel of markers.
Weiner CP, Dong Y, Zhou H, Cuckle H, Ramsey R, Egerman R, Buhimschi I, Buhimschi C. Weiner CP, et al. Among authors: cuckle h. BJOG. 2021 Oct;128(11):1870-1880. doi: 10.1111/1471-0528.16736. Epub 2021 May 27. BJOG. 2021. PMID: 33969600 Free PMC article.
OBJECTIVE: To compare the second-trimester plasma cell-free (PCF) transcriptome of women who delivered at term with that of women with spontaneous preterm birth (sPTB) at or before 32 weeks of gestation and identify/validate PCF RNA markers present by 16 weeks of ge …
OBJECTIVE: To compare the second-trimester plasma cell-free (PCF) transcriptome of women who delivered at term with that of women wit …
Oligohydramnios: how severe is severe?
Zilberman Sharon N, Pekar-Zlotin M, Kugler N, Accart Z, Nimrodi M, Melcer Y, Cuckle H, Maymon R. Zilberman Sharon N, et al. Among authors: cuckle h. J Matern Fetal Neonatal Med. 2022 Dec;35(25):5754-5760. doi: 10.1080/14767058.2021.1892068. Epub 2021 Feb 28. J Matern Fetal Neonatal Med. 2022. PMID: 33645394
OBJECTIVE: To investigate whether the severity of isolated oligohydramnios at term is associated with increased rates of adverse perinatal outcome. ...All low-risk pregnancies with incidental isolated oligohydramnios at term were included. The degree of oligohydramn …
OBJECTIVE: To investigate whether the severity of isolated oligohydramnios at term is associated with increased rates of adverse peri …
Annual mammographic screening to reduce breast cancer mortality in women from age 40 years: long-term follow-up of the UK Age RCT.
Duffy S, Vulkan D, Cuckle H, Parmar D, Sheikh S, Smith R, Evans A, Blyuss O, Johns L, Ellis I, Sasieni P, Wale C, Myles J, Moss S. Duffy S, et al. Among authors: cuckle h. Health Technol Assess. 2020 Oct;24(55):1-24. doi: 10.3310/hta24550. Health Technol Assess. 2020. PMID: 33141657 Free PMC article. Clinical Trial.
BACKGROUND: There remains disagreement on the long-term effect of mammographic screening in women aged 40-49 years. OBJECTIVES: The long-term follow-up of a randomised controlled trial that offered annual mammography to women aged 40-49 years. ...
BACKGROUND: There remains disagreement on the long-term effect of mammographic screening in women aged 40-49 years. OBJECTIVES: The l …
Maternal age in the epidemiology of common autosomal trisomies.
Cuckle H, Morris J. Cuckle H, et al. Prenat Diagn. 2021 Apr;41(5):573-583. doi: 10.1002/pd.5840. Epub 2020 Oct 19. Prenat Diagn. 2021. PMID: 33078428 Review.
The birth prevalence rate of each common autosomal trisomy generally increases with advancing maternal age and there is a substantial fetal loss rate between late first trimester and term. ...There is no evidence of the claimed relatively high birth prevalenc …
The birth prevalence rate of each common autosomal trisomy generally increases with advancing maternal age and there is a substantial …
Effect of mammographic screening from age 40 years on breast cancer mortality (UK Age trial): final results of a randomised, controlled trial.
Duffy SW, Vulkan D, Cuckle H, Parmar D, Sheikh S, Smith RA, Evans A, Blyuss O, Johns L, Ellis IO, Myles J, Sasieni PD, Moss SM. Duffy SW, et al. Among authors: cuckle h. Lancet Oncol. 2020 Sep;21(9):1165-1172. doi: 10.1016/S1470-2045(20)30398-3. Epub 2020 Aug 12. Lancet Oncol. 2020. PMID: 32800099 Free PMC article. Clinical Trial.
Women were included in the primary comparison regardless of compliance with randomisation status (intention-to-treat analysis). This Article reports on long-term follow-up analysis. The trial is registered with the ISRCTN registry, ISRCTN24647151. ...
Women were included in the primary comparison regardless of compliance with randomisation status (intention-to-treat analysis). This Article …
Late pregnancy screening for preeclampsia with a urinary point-of-care test for misfolded proteins.
Li XM, Liu XM, Xu J, Du J, Cuckle H. Li XM, et al. Among authors: cuckle h. PLoS One. 2020 May 20;15(5):e0233214. doi: 10.1371/journal.pone.0233214. eCollection 2020. PLoS One. 2020. PMID: 32433710 Free PMC article.
A total of 140 preeclampsia cases were clinically diagnosed, 101 severe and 87 pre-term. Detection and false positive rates were similar in the training and validation subsets with combined 74% and 3.0%. The detection rate was 83% in severe, 86% in pre-term, 49% and …
A total of 140 preeclampsia cases were clinically diagnosed, 101 severe and 87 pre-term. Detection and false positive rates were simi …
Down's Syndrome Screening in the First Trimester with Additional Serum Markers: Indian Parameters.
Suresh S, Cuckle HS, Jagadeesh S, Ghosh K, Vemavarapu G, Taval T, Suresh S. Suresh S, et al. Among authors: cuckle hs. J Obstet Gynaecol India. 2020 Feb;70(1):12-17. doi: 10.1007/s13224-018-1198-1. Epub 2019 Feb 11. J Obstet Gynaecol India. 2020. PMID: 32030000 Free PMC article.
RESULTS: The model predicted a detection rate for a serum-only protocol of 80% for a 5% false-positive rate. Using a 1 in 250 at term Down's syndrome risk cut-off, the predicted detection rate was 78% and the false-positive rate was 4.1%. ...
RESULTS: The model predicted a detection rate for a serum-only protocol of 80% for a 5% false-positive rate. Using a 1 in 250 at term …
Effect of mammographic screening from age 40 years on breast cancer mortality in the UK Age trial at 17 years' follow-up: a randomised controlled trial.
Moss SM, Wale C, Smith R, Evans A, Cuckle H, Duffy SW. Moss SM, et al. Among authors: cuckle h. Lancet Oncol. 2015 Sep;16(9):1123-1132. doi: 10.1016/S1470-2045(15)00128-X. Epub 2015 Jul 20. Lancet Oncol. 2015. PMID: 26206144 Clinical Trial.
INTERPRETATION: Our results support an early reduction in mortality from breast cancer with annual mammography screening in women aged 40-49 years. Further data are needed to fully understand long-term effects. Cumulative incidence figures suggest at worst a small amount o …
INTERPRETATION: Our results support an early reduction in mortality from breast cancer with annual mammography screening in women aged 40-49 …
27 results