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Control of vaccinia virus skin lesions by long-term-maintained IFN-gamma+TNF-alpha+ effector/memory CD4+ lymphocytes in humans.
Puissant-Lubrano B, Bossi P, Gay F, Crance JM, Bonduelle O, Garin D, Bricaire F, Autran B, Combadière B. Puissant-Lubrano B, et al. Among authors: crance jm. J Clin Invest. 2010 May;120(5):1636-44. doi: 10.1172/JCI38506. Epub 2010 Apr 1. J Clin Invest. 2010. PMID: 20364089 Free PMC article.
While antibody responses have been widely proposed as a correlate of efficacy and protection in humans, the role of cellular and humoral immunity in VV-associated skin lesion formation was unknown. We therefore investigated whether long-term residual humoral and cellular i …
While antibody responses have been widely proposed as a correlate of efficacy and protection in humans, the role of cellular and humoral imm …
Short- and long-term immunogenicity and protection induced by non-replicating smallpox vaccine candidates in mice and comparison with the traditional 1st generation vaccine.
Ferrier-Rembert A, Drillien R, Tournier JN, Garin D, Crance JM. Ferrier-Rembert A, et al. Among authors: crance jm. Vaccine. 2008 Mar 25;26(14):1794-804. doi: 10.1016/j.vaccine.2007.12.059. Epub 2008 Feb 12. Vaccine. 2008. PMID: 18336966
Prime-boost vaccination enabled effective long-term protection from death for mice vaccinated with MVA, but protection from disease and CD4(+) T-cell level were lower than the ones induced by the traditional vaccine over the long-term period. Further investigations …
Prime-boost vaccination enabled effective long-term protection from death for mice vaccinated with MVA, but protection from disease a …