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Rapid outpatient transient ischemic attack clinic and stroke service activity during the SARS-CoV-2 pandemic: a multicenter time series analysis.
Lim A, Rothwell PM, Li L, Coutts SB, Hill MD, Guarino M, Barone V, Rondelli F, Kleinig T, Cornell-Farrow R, Krause M, Wronski M, Singhal S, Ma H, Phan TG. Lim A, et al. Among authors: coutts sb. Front Neurol. 2024 Feb 7;15:1351769. doi: 10.3389/fneur.2024.1351769. eCollection 2024. Front Neurol. 2024. PMID: 38385034 Free PMC article.
BACKGROUND AND AIM: Rapid outpatient evaluation and treatment of TIA in structured clinics have been shown to reduce stroke recurrence. It is unclear whether short-term downtrends in TIA incidence and admissions have had enduring impact on TIA clinic activity. ...
BACKGROUND AND AIM: Rapid outpatient evaluation and treatment of TIA in structured clinics have been shown to reduce stroke recurrence. It i …
Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.
Healey JS, Lopes RD, Granger CB, Alings M, Rivard L, McIntyre WF, Atar D, Birnie DH, Boriani G, Camm AJ, Conen D, Erath JW, Gold MR, Hohnloser SH, Ip J, Kautzner J, Kutyifa V, Linde C, Mabo P, Mairesse G, Benezet Mazuecos J, Cosedis Nielsen J, Philippon F, Proietti M, Sticherling C, Wong JA, Wright DJ, Zarraga IG, Coutts SB, Kaplan A, Pombo M, Ayala-Paredes F, Xu L, Simek K, Nevills S, Mian R, Connolly SJ; ARTESIA Investigators. Healey JS, et al. Among authors: coutts sb. N Engl J Med. 2024 Jan 11;390(2):107-117. doi: 10.1056/NEJMoa2310234. Epub 2023 Nov 12. N Engl J Med. 2024. PMID: 37952132 Clinical Trial.
BACKGROUND: Subclinical atrial fibrillation is short-lasting and asymptomatic and can usually be detected only by long-term continuous monitoring with pacemakers or defibrillators. Subclinical atrial fibrillation is associated with an increased risk of stroke by a factor o …
BACKGROUND: Subclinical atrial fibrillation is short-lasting and asymptomatic and can usually be detected only by long-term continuou …
Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy.
Halliday A, Bulbulia R, Bonati LH, Chester J, Cradduck-Bamford A, Peto R, Pan H; ACST-2 Collaborative Group. Halliday A, et al. Lancet. 2021 Sep 18;398(10305):1065-1073. doi: 10.1016/S0140-6736(21)01910-3. Epub 2021 Aug 29. Lancet. 2021. PMID: 34469763 Free PMC article. Clinical Trial.
Comparison of their long-term protective effects requires large-scale randomised evidence. ...INTERPRETATION: Serious complications are similarly uncommon after competent CAS and CEA, and the long-term effects of these two carotid artery procedures on fatal or disab …
Comparison of their long-term protective effects requires large-scale randomised evidence. ...INTERPRETATION: Serious complications a …
Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.
Best JG, Ambler G, Wilson D, Lee KJ, Lim JS, Shiozawa M, Koga M, Li L, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats-Sanchez L, Martínez-Domeño A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Ben Assayag E, Hallevi H, Molad J, Nishihara M, Tanaka J, Coutts SB, Polymeris A, Wagner B, Seiffge DJ, Lyrer P, Algra A, Kappelle LJ, Al-Shahi Salman R, Jäger HR, Lip GYH, Fischer U, El-Koussy M, Mas JL, Legrand L, Karayiannis C, Phan T, Gunkel S, Christ N, Abrigo J, Leung T, Chu W, Chappell F, Makin S, Hayden D, Williams DJ, Mess WH, Nederkoorn PJ, Barbato C, Browning S, Wiegertjes K, Tuladhar AM, Maaijwee N, Guevarra AC, Yatawara C, Mendyk AM, Delmaire C, Köhler S, van Oostenbrugge R, Zhou Y, Xu C, Hilal S, Gyanwali B, Chen C, Lou M, Staals J, Bordet R, Kandiah N, de Leeuw FE, Simister R, Hendrikse J, Kelly PJ, Wardlaw J, Soo Y, Fluri F, Srikanth V, Calvet D, Jung S, Kwa VIH, Engelter ST, Peters N, Smith EE, Hara H, Yakushiji Y, Orken DN, Fazekas F, Thijs V, Heo JH, Mok V, Veltkamp R, Ay H, Imaizumi T, Gomez-Anson B, Lau KK, Jouvent E, Rothwell P… See abstract for full author list ➔ Best JG, et al. Among authors: coutts sb. Lancet Neurol. 2021 Apr;20(4):294-303. doi: 10.1016/S1474-4422(21)00024-7. Epub 2021 Mar 17. Lancet Neurol. 2021. PMID: 33743239
INTERPRETATION: The MICON risk scores, incorporating clinical variables and cerebral microbleeds, offer predictive value for the long-term risks of intracranial haemorrhage and ischaemic stroke in patients prescribed antithrombotic therapy for secondary stroke prevention; …
INTERPRETATION: The MICON risk scores, incorporating clinical variables and cerebral microbleeds, offer predictive value for the long-ter …
Association of White Matter Hyperintensities With Short-Term Outcomes in Patients With Minor Cerebrovascular Events.
Zerna C, Yu AYX, Modi J, Patel SK, Coulter JI, Smith EE, Coutts SB. Zerna C, et al. Among authors: coutts sb. Stroke. 2018 Apr;49(4):919-923. doi: 10.1161/STROKEAHA.117.017429. Epub 2018 Mar 14. Stroke. 2018. PMID: 29540612
CONCLUSIONS: Our data suggest that quantitative and qualitative WML assessments are highly correlated and comparable in TIA/minor stroke patients. WML burden is associated with short-term outcome of patients with good prestroke function in the presence of intracranial sten …
CONCLUSIONS: Our data suggest that quantitative and qualitative WML assessments are highly correlated and comparable in TIA/minor stroke pat …
The Alberta Stroke Prevention in TIAs and mild strokes (ASPIRE) intervention: rationale and design for evaluating the implementation of a province-wide TIA triaging system.
Jeerakathil T, Shuaib A, Majumdar SR, Demchuk AM, Butcher KS, Watson TJ, Dean N, Gordon D, Edmond C, Coutts SB; ASPIRE Investigators. Jeerakathil T, et al. Among authors: coutts sb. Int J Stroke. 2014 Oct;9 Suppl A100:135-43. doi: 10.1111/j.1747-4949.2012.00881.x. Epub 2012 Oct 23. Int J Stroke. 2014. PMID: 23088263
A prospective transient ischaemic attack cohort will also be concurrently created with telephone follow-up at seven-days and 90 days as well as passive follow-up over the longer term using linkages to provincial healthcare administrative databases. ...
A prospective transient ischaemic attack cohort will also be concurrently created with telephone follow-up at seven-days and 90 days as well …
Incidence of radiocontrast nephropathy in patients undergoing acute stroke computed tomography angiography.
Krol AL, Dzialowski I, Roy J, Puetz V, Subramaniam S, Coutts SB, Demchuk AM. Krol AL, et al. Among authors: coutts sb. Stroke. 2007 Aug;38(8):2364-6. doi: 10.1161/STROKEAHA.107.482778. Epub 2007 Jun 28. Stroke. 2007. PMID: 17600231
BACKGROUND AND PURPOSE: Minimal research has evaluated the renal safety of emergent computed tomography angiography (CTA) procedures, consecutive contrast medium application, and the long-term outcome in acute stroke patients. We investigated the incidence of contrast-indu …
BACKGROUND AND PURPOSE: Minimal research has evaluated the renal safety of emergent computed tomography angiography (CTA) procedures, consec …
Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion-derived blood flow and blood volume measurements.
Murphy BD, Fox AJ, Lee DH, Sahlas DJ, Black SE, Hogan MJ, Coutts SB, Demchuk AM, Goyal M, Aviv RI, Symons S, Gulka IB, Beletsky V, Pelz D, Hachinski V, Chan R, Lee TY. Murphy BD, et al. Among authors: coutts sb. Stroke. 2006 Jul;37(7):1771-7. doi: 10.1161/01.STR.0000227243.96808.53. Epub 2006 Jun 8. Stroke. 2006. PMID: 16763182
CBV in the penumbra (2.15+/-0.43 mL x 100 g(-1)) was significantly higher than contralateral (1.78+/-0.30 mL x 100 g(-1)) and infarcted tissue (1.12+/-0.37 mL x 100 g(-1)). Logistic regression using an interaction term (CBFxCBV) resulted in sensitivity, specificity, and ac …
CBV in the penumbra (2.15+/-0.43 mL x 100 g(-1)) was significantly higher than contralateral (1.78+/-0.30 mL x 100 g(-1)) and infarcted tiss …
Extent of early ischemic changes on computed tomography (CT) before thrombolysis: prognostic value of the Alberta Stroke Program Early CT Score in ECASS II.
Dzialowski I, Hill MD, Coutts SB, Demchuk AM, Kent DM, Wunderlich O, von Kummer R. Dzialowski I, et al. Among authors: coutts sb. Stroke. 2006 Apr;37(4):973-8. doi: 10.1161/01.STR.0000206215.62441.56. Epub 2006 Feb 23. Stroke. 2006. PMID: 16497977
However, a treatment-by-ASPECTS effect modification was seen in predicting PH (0.043 for the interaction term), indicating a much higher likelihood of thrombolytic-related parenchymal hemorrhage in those with ASPECTS < or =7. ...
However, a treatment-by-ASPECTS effect modification was seen in predicting PH (0.043 for the interaction term), indicating a much hig …