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Renal dysfunction in cystic fibrosis: is there cause for concern?
Soulsby N, Greville H, Coulthard K, Doecke C. Soulsby N, et al. Among authors: coulthard k. Pediatr Pulmonol. 2009 Oct;44(10):947-53. doi: 10.1002/ppul.21086. Pediatr Pulmonol. 2009. PMID: 19728391 Review.
One of the less obvious concerns is that of renal dysfunction associated with long-term exposure to aminoglycosides as well as renally toxic immunosuppressants in lung transplant recipients. ...
One of the less obvious concerns is that of renal dysfunction associated with long-term exposure to aminoglycosides as well as renall …
Efficacy of once-daily tobramycin monotherapy for acute pulmonary exacerbations of cystic fibrosis: a preliminary study.
Master V, Roberts GW, Coulthard KP, Baghurst PA, Martin A, Roberts ME, Onishko CR, Martin AJ, Linke RJ, Holmes M, Jarvinen A, Kennedy D, Colebatch KA, Hansman D, Parsons DW. Master V, et al. Among authors: coulthard kp. Pediatr Pulmonol. 2001 May;31(5):367-76. doi: 10.1002/ppul.1060. Pediatr Pulmonol. 2001. PMID: 11340683 Clinical Trial.
Tobramycin doses were adjusted to achieve a daily area under the time-concentration curve of 100 mg x hr/L in both groups. Results were assessed for both short-term changes (efficacy and safety after 10 days of IV antibiotics during acute exacerbations) and long-term
Tobramycin doses were adjusted to achieve a daily area under the time-concentration curve of 100 mg x hr/L in both groups. Results were asse …