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Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis.
D'Onofrio F, Renga G, Puccetti M, Pariano M, Bellet MM, Santarelli I, Stincardini C, Mosci P, Ricci M, Giovagnoli S, Costantini C, Romani L. D'Onofrio F, et al. Among authors: costantini c. Cells. 2021 Jun 29;10(7):1622. doi: 10.3390/cells10071622. Cells. 2021. PMID: 34209524 Free PMC article.
Primary sclerosing cholangitis (PSC) is a long-term liver disease characterized by a progressive course of cholestasis with liver inflammation and fibrosis. ...
Primary sclerosing cholangitis (PSC) is a long-term liver disease characterized by a progressive course of cholestasis with liver inf …
Comparative clinical performance of two types of drug-eluting stents with abluminal biodegradable polymer coating: Five-year results of the DESTINY randomized trial.
Prado GFA Jr, Abizaid AAC, Meireles GC, Sarmento-Leite R, Prudente M, Cantarelli M, Dourado AD, Jr JM, Perin MA, Costantini C, Costa R, Costa JR, Chamie D, Campos CM, Ribeiro EE, Lemos PA. Prado GFA Jr, et al. Among authors: costantini c. Rev Port Cardiol (Engl Ed). 2021 Feb;40(2):71-76. doi: 10.1016/j.repc.2020.05.017. Epub 2021 Jan 2. Rev Port Cardiol (Engl Ed). 2021. PMID: 33402278 Free article. Clinical Trial. English, Portuguese.
CONCLUSIONS: The novel Inspiron stent had similar good clinical performance in long-term follow-up when compared head-to-head with the control latest-generation Biomatrix Flex biolimus-eluting stent....
CONCLUSIONS: The novel Inspiron stent had similar good clinical performance in long-term follow-up when compared head-to-head with th …
Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease.
Stone GW, Kappetein AP, Sabik JF, Pocock SJ, Morice MC, Puskas J, Kandzari DE, Karmpaliotis D, Brown WM 3rd, Lembo NJ, Banning A, Merkely B, Horkay F, Boonstra PW, van Boven AJ, Ungi I, Bogáts G, Mansour S, Noiseux N, Sabaté M, Pomar J, Hickey M, Gershlick A, Buszman PE, Bochenek A, Schampaert E, Pagé P, Modolo R, Gregson J, Simonton CA, Mehran R, Kosmidou I, Généreux P, Crowley A, Dressler O, Serruys PW; EXCEL Trial Investigators. Stone GW, et al. N Engl J Med. 2019 Nov 7;381(19):1820-1830. doi: 10.1056/NEJMoa1909406. Epub 2019 Sep 28. N Engl J Med. 2019. PMID: 31562798 Free article. Clinical Trial.
BACKGROUND: Long-term outcomes after percutaneous coronary intervention (PCI) with contemporary drug-eluting stents, as compared with coronary-artery bypass grafting (CABG), in patients with left main coronary artery disease are not clearly established. ...
BACKGROUND: Long-term outcomes after percutaneous coronary intervention (PCI) with contemporary drug-eluting stents, as compared with …
Association mapping desiccation resistance within chromosomal inversions in the African malaria vector Anopheles gambiae.
Ayala D, Zhang S, Chateau M, Fouet C, Morlais I, Costantini C, Hahn MW, Besansky NJ. Ayala D, et al. Among authors: costantini c. Mol Ecol. 2019 Mar;28(6):1333-1342. doi: 10.1111/mec.14880. Epub 2018 Oct 22. Mol Ecol. 2019. PMID: 30252170 Free PMC article.
However, the same features that ensure their large role in local adaptation-especially reduced recombination between alternate arrangements-mean that uncovering the precise loci within inversions that control these phenotypes is unachievable using standard mapping approaches. Her …
However, the same features that ensure their large role in local adaptation-especially reduced recombination between alternate arrangements- …
Stem-cell therapy in ST-segment elevation myocardial infarction with reduced ejection fraction: A multicenter, double-blind randomized trial.
Nicolau JC, Furtado RHM, Silva SA, Rochitte CE, Rassi A Jr, Moraes JBMC Jr, Quintella E, Costantini CR, Korman APM, Mattos MA, Castello HJ Jr, Caixeta A, Dohmann HFR, de Carvalho ACC; MiHeart/AMI Investigators. Nicolau JC, et al. Among authors: costantini cr. Clin Cardiol. 2018 Mar;41(3):392-399. doi: 10.1002/clc.22882. Epub 2018 Mar 22. Clin Cardiol. 2018. PMID: 29569254 Free PMC article. Clinical Trial.
BACKGROUND: Left ventricular ejection fraction (LVEF) is a major determinant of long-term prognosis after ST-segment elevation myocardial infarction (STEMI). ...
BACKGROUND: Left ventricular ejection fraction (LVEF) is a major determinant of long-term prognosis after ST-segment elevation myocar …
Opportunities for improvement in anti-thrombotic therapy and other strategies for the management of acute coronary syndromes: Insights from EPICOR, an international study of current practice patterns.
Bueno H, Sinnaeve P, Annemans L, Danchin N, Licour M, Medina J, Pocock S, Sánchez-Covisa J, Storey RF, Jukema JW, Zeymer U, Van de Werf F; EPICOR Investigators. Bueno H, et al. Eur Heart J Acute Cardiovasc Care. 2016 Feb;5(1):3-12. doi: 10.1177/2048872614565912. Epub 2015 Jan 5. Eur Heart J Acute Cardiovasc Care. 2016. PMID: 25561688
AIMS: To describe international patterns and opportunities for improvement of pre- and in-hospital care of patients hospitalized for acute coronary syndromes (ACS), with special focus on anti-thrombotic therapy. METHODS AND RESULTS: EPICOR (long-tErm follow-uP of anti-thro …
AIMS: To describe international patterns and opportunities for improvement of pre- and in-hospital care of patients hospitalized for acute c …
Edoxaban versus warfarin in patients with atrial fibrillation.
Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, Waldo AL, Ezekowitz MD, Weitz JI, Špinar J, Ruzyllo W, Ruda M, Koretsune Y, Betcher J, Shi M, Grip LT, Patel SP, Patel I, Hanyok JJ, Mercuri M, Antman EM; ENGAGE AF-TIMI 48 Investigators. Giugliano RP, et al. N Engl J Med. 2013 Nov 28;369(22):2093-104. doi: 10.1056/NEJMoa1310907. Epub 2013 Nov 19. N Engl J Med. 2013. PMID: 24251359 Free article. Clinical Trial.
BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. ...
BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of ed …
Short-term effects of moderate intensity physical activity in patients with metabolic syndrome.
Colombo CM, de Macedo RM, Fernandes-Silva MM, Caporal AM, Stinghen AE, Costantini CR, Baena CP, Guarita-Souza LC, Faria-Neto JR. Colombo CM, et al. Among authors: costantini cr. Einstein (Sao Paulo). 2013 Jul-Sep;11(3):324-30. doi: 10.1590/s1679-45082013000300011. Einstein (Sao Paulo). 2013. PMID: 24136759 Free PMC article.
OBJECTIVES: To evaluate whether a short-term moderate intensity exercise program could change inflammatory parameters, and improve different components of metabolic syndrome in sedentary patients. ...
OBJECTIVES: To evaluate whether a short-term moderate intensity exercise program could change inflammatory parameters, and improve di …
Implications of myocardial reperfusion on survival in women versus men with acute myocardial infarction undergoing primary coronary intervention.
Meller SM, Lansky AJ, Costa RA, Soffler M, Costantini CO, Brodie BR, Cox DA, Stuckey TD, Fahy M, Grines CL, Stone GW. Meller SM, et al. Among authors: costantini co. Am J Cardiol. 2013 Oct 15;112(8):1087-92. doi: 10.1016/j.amjcard.2013.05.052. Epub 2013 Jul 2. Am J Cardiol. 2013. PMID: 23827398 Clinical Trial.
Whether the incidence and prognosis of myocardial perfusion differs according to gender among patients with AMI undergoing PCI is unknown. MBG and short- and long-term mortality were evaluated in 1,301 patients (male = 935; female = 366) with AMI randomized to primary angi …
Whether the incidence and prognosis of myocardial perfusion differs according to gender among patients with AMI undergoing PCI is unknown. M …
Acute effects of prolonged physical exercise: evaluation after a twenty-four-hour ultramarathon.
Passaglia DG, Emed LG, Barberato SH, Guerios ST, Moser AI, Silva MM, Ishie E, Guarita-Souza LC, Costantini CR, Faria-Neto JR. Passaglia DG, et al. Among authors: costantini cr. Arq Bras Cardiol. 2013 Jan;100(1):21-8. doi: 10.1590/s0066-782x2012005000118. Epub 2012 Dec 18. Arq Bras Cardiol. 2013. PMID: 23250832 Free article. English, Portuguese.
Cardiac abnormalities found in our study suggest that cardiac fatigue may occur in this specific race modality. The long-term effect of these alterations, while maintaining the routine practice of prolonged strenuous physical activity, is still unknown....
Cardiac abnormalities found in our study suggest that cardiac fatigue may occur in this specific race modality. The long-term effect …
20 results