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Calcium carbonate suppresses haem toxicity markers without calcium phosphate side effects on colon carcinogenesis.
Allam O, Bahuaud D, Taché S, Naud N, Corpet DE, Pierre FH. Allam O, et al. Among authors: corpet de. Br J Nutr. 2011 Feb;105(3):384-92. doi: 10.1017/S0007114510003624. Epub 2010 Dec 7. Br J Nutr. 2011. PMID: 21134327 Free PMC article.
The present study was designed to find a Ca supplementation with no adverse effect, by testing several doses and types of Ca salts. One in vitro study and two short-term studies in rats identified calcium carbonate as the most effective Ca salt to bind haem in vitro and to …
The present study was designed to find a Ca supplementation with no adverse effect, by testing several doses and types of Ca salts. One in v …
Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colon.
Pierre FH, Santarelli RL, Allam O, Tache S, Naud N, Gueraud F, Corpet DE. Pierre FH, et al. Among authors: corpet de. Nutr Cancer. 2010;62(5):567-73. doi: 10.1080/01635580903532408. Nutr Cancer. 2010. PMID: 20574917 Free PMC article.
Promotion was associated with cytotoxicity and lipid peroxidation. In the short-term study, cytotoxicity and lipid peroxidation of fecal water, and the urinary marker of lipid peroxidation, increased dramatically in ham- and hemin-fed rat. ...
Promotion was associated with cytotoxicity and lipid peroxidation. In the short-term study, cytotoxicity and lipid peroxidation of fe …
New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic acid.
Pierre F, Peiro G, Taché S, Cross AJ, Bingham SA, Gasc N, Gottardi G, Corpet DE, Guéraud F. Pierre F, et al. Among authors: corpet de. Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2274-9. doi: 10.1158/1055-9965.EPI-06-0085. Cancer Epidemiol Biomarkers Prev. 2006. PMID: 17119057 Clinical Trial.
METHODS: We measured urinary excretion of 8-iso-PGF(2)alpha and 1,4-dihydroxynonane mercapturic acid (DHN-MA), the major urinary metabolite of 4-hydroxynonenal, in three studies. In a short-term and a carcinogenesis long-term animal study, we fed rats four different …
METHODS: We measured urinary excretion of 8-iso-PGF(2)alpha and 1,4-dihydroxynonane mercapturic acid (DHN-MA), the major urinary metabolite …
Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens.
Corpet DE, Parnaud G, Delverdier M, Peiffer G, Taché S. Corpet DE, et al. Cancer Res. 2000 Jun 15;60(12):3160-4. Cancer Res. 2000. PMID: 10866305
To determine the consistency of this preventive effect, we carried out a long-term study in rats fed the standard American Institute of Nutrition 1976 diet, and 7 short-term prevention studies in rodents. ...
To determine the consistency of this preventive effect, we carried out a long-term study in rats fed the standard American Institute …
Diet, aberrant crypt foci and colorectal cancer.
Bruce WR, Archer MC, Corpet DE, Medline A, Minkin S, Stamp D, Yin Y, Zhang XM. Bruce WR, et al. Among authors: corpet de. Mutat Res. 1993 Nov;290(1):111-8. doi: 10.1016/0027-5107(93)90038-h. Mutat Res. 1993. PMID: 7694090 Review.
The importance of these hypotheses has still to be tested in long term carcinogenesis experiments, in analytic epidemiology studies and then, perhaps, in intervention trials....
The importance of these hypotheses has still to be tested in long term carcinogenesis experiments, in analytic epidemiology studies a …