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Post-stroke gaseous hypothermia increases vascular density but not neurogenesis in the ischemic penumbra of aged rats.
Sandu RE, Uzoni A, Ciobanu O, Moldovan M, Anghel A, Radu E, Coogan AN, Popa-Wagner A. Sandu RE, et al. Among authors: coogan an. Restor Neurol Neurosci. 2016 Feb 24;34(3):401-14. doi: 10.3233/RNN-150600. Restor Neurol Neurosci. 2016. PMID: 26923618
PURPOSE: In aged humans, stroke is a major cause of disability for which no neuroprotective measures are available. In animal studies of focal ischemia, short-term hypothermia often reduces infarct size. Nevertheless, efficient neuroprotection requires long-term, re …
PURPOSE: In aged humans, stroke is a major cause of disability for which no neuroprotective measures are available. In animal studies of foc …
Long-lasting effects of sepsis on circadian rhythms in the mouse.
O'Callaghan EK, Anderson ST, Moynagh PN, Coogan AN. O'Callaghan EK, et al. Among authors: coogan an. PLoS One. 2012;7(10):e47087. doi: 10.1371/journal.pone.0047087. Epub 2012 Oct 11. PLoS One. 2012. PMID: 23071720 Free PMC article.
Previous studies have indicated reciprocal relationships between the circadian and the immune systems, although to date there have been only limited explorations of the long-term modulation of the circadian system by immune challenge, and it is to this question that we add …
Previous studies have indicated reciprocal relationships between the circadian and the immune systems, although to date there have been only …
The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1beta on long-term potentiation in the rat dentate gyrus in vitro.
Coogan AN, O'Neill LA, O'Connor JJ. Coogan AN, et al. Neuroscience. 1999;93(1):57-69. doi: 10.1016/s0306-4522(99)00100-1. Neuroscience. 1999. PMID: 10430470
To investigate a possible role for interleukin-1beta in the normal expression of long-term potentiation, the interleukin-1 receptor antagonist (25 ng/ml) was applied during the maintenance phase of long-term potentiation. This was found to depress the sustained expr …
To investigate a possible role for interleukin-1beta in the normal expression of long-term potentiation, the interleukin-1 receptor a …
Interleukin-1beta inhibits a tetraethylammonium-induced synaptic potentiation in the rat dentate gyrus in vitro.
Coogan AN, O'Connor JJ. Coogan AN, et al. Eur J Pharmacol. 1999 Jun 18;374(2):197-206. doi: 10.1016/s0014-2999(99)00320-9. Eur J Pharmacol. 1999. PMID: 10422760
Perfusion of the K+ channel blocker, tetraethylammonium chloride (25 mM) for 10 min and subsequent washout gave rise to robust and long-term potentiation of the field EPSP slope (tetraethylammonium induced long-term potentiation; 125+/-5% of baseline 60 min followin …
Perfusion of the K+ channel blocker, tetraethylammonium chloride (25 mM) for 10 min and subsequent washout gave rise to robust and long-t …
P42/44 MAP kinase inhibitor PD98059 attenuates multiple forms of synaptic plasticity in rat dentate gyrus in vitro.
Coogan AN, O'Leary DM, O'Connor JJ. Coogan AN, et al. J Neurophysiol. 1999 Jan;81(1):103-10. doi: 10.1152/jn.1999.81.1.103. J Neurophysiol. 1999. PMID: 9914271 Free article.
The effects of the specific p42/44 mitogen-activated protein (MAP) kinase cascade inhibitor, PD98059, were investigated on three types of long-term potentiation (LTP) in the medial perforant path of the rat dentate gyrus in vitro: LTP induced by 1) high-frequency stimulati …
The effects of the specific p42/44 mitogen-activated protein (MAP) kinase cascade inhibitor, PD98059, were investigated on three types of lo …