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Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation.
Mohebi A, Collins VL, Berke JD. Mohebi A, et al. Among authors: collins vl. Elife. 2023 Jun 5;12:e85011. doi: 10.7554/eLife.85011. Elife. 2023. PMID: 37272423 Free PMC article.
CIN stimulation rapidly evoked DA release, and in contrast to slice preparations, this DA release showed no indication of short-term depression or receptor desensitization. The sound of unexpected food delivery evoked a brief joint increase in CIN population activity and D …
CIN stimulation rapidly evoked DA release, and in contrast to slice preparations, this DA release showed no indication of short-term
Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non-inferiority trial.
SoSTART Collaboration. SoSTART Collaboration. Lancet Neurol. 2021 Oct;20(10):842-853. doi: 10.1016/S1474-4422(21)00264-7. Epub 2021 Sep 3. Lancet Neurol. 2021. PMID: 34487722
Web-based computerised randomisation incorporating a minimisation algorithm allocated participants (1:1) to start or avoid long-term (1 year) full treatment dose open-label oral anticoagulation. ...
Web-based computerised randomisation incorporating a minimisation algorithm allocated participants (1:1) to start or avoid long-term
Prevalence, radiographic resolution and outcomes of slab fractures of the third and central tarsal bones in juvenile Thoroughbred horses.
Steel CM, Collins VL, Hance SR, Adkins AR, Hitchens PL. Steel CM, et al. Among authors: collins vl. Aust Vet J. 2019 Apr;97(4):108-115. doi: 10.1111/avj.12790. Aust Vet J. 2019. PMID: 30919440
Further investigation is required to determine risk factors and before making firm conclusions regarding the optimal management, prognosis for racing and long-term soundness....
Further investigation is required to determine risk factors and before making firm conclusions regarding the optimal management, prognosis f …
Influence of Gestational Age at Initiation of Antihypertensive Therapy: Secondary Analysis of CHIPS Trial Data (Control of Hypertension in Pregnancy Study).
Pels A, Mol BWJ, Singer J, Lee T, von Dadelszen P, Ganzevoort W, Asztalos E, Magee LA; CHIPS Study Group. Pels A, et al. Hypertension. 2018 Jun;71(6):1170-1177. doi: 10.1161/HYPERTENSIONAHA.117.10689. Epub 2018 Apr 23. Hypertension. 2018. PMID: 29686009 Free PMC article. Clinical Trial.
For the 981 women with nonsevere, chronic or gestational hypertension randomized to less-tight (target diastolic blood pressure, 100 mm Hg), or tight (target, 85 mm Hg) control, we used mixed-effects logistic regression to examine whether the effect of less-tight (versus tight) c …
For the 981 women with nonsevere, chronic or gestational hypertension randomized to less-tight (target diastolic blood pressure, 100 mm Hg), …
Long-term effect of critical illness after severe paediatric burn injury on cardiac function in adolescent survivors: an observational study.
Hundeshagen G, Herndon DN, Clayton RP, Wurzer P, McQuitty A, Jennings K, Branski L, Collins VN, Marques NR, Finnerty CC, Suman OE, Kinsky MP. Hundeshagen G, et al. Among authors: collins vn. Lancet Child Adolesc Health. 2017 Dec;1(4):293-301. doi: 10.1016/S2352-4642(17)30122-0. Epub 2017 Oct 20. Lancet Child Adolesc Health. 2017. PMID: 29581998 Free PMC article.
BACKGROUND: Sepsis, trauma, and burn injury acutely depress systolic and diastolic cardiac function; data on long-term cardiac sequelae of pediatric critical illness are sparse. This study evaluated long-term systolic and diastolic function, myocardial fibrosis, and …
BACKGROUND: Sepsis, trauma, and burn injury acutely depress systolic and diastolic cardiac function; data on long-term cardiac sequel …
Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain.
Geisenberger C, Mock A, Warta R, Rapp C, Schwager C, Korshunov A, Nied AK, Capper D, Brors B, Jungk C, Jones D, Collins VP, Ichimura K, Bäcklund LM, Schnabel E, Mittelbron M, Lahrmann B, Zheng S, Verhaak RG, Grabe N, Pfister SM, Hartmann C, von Deimling A, Debus J, Unterberg A, Abdollahi A, Herold-Mende C. Geisenberger C, et al. Among authors: collins vp. Acta Neuropathol. 2015 Sep;130(3):419-34. doi: 10.1007/s00401-015-1427-y. Epub 2015 May 1. Acta Neuropathol. 2015. PMID: 25931051
Glioblastoma (GBM) is a devastating tumor and few patients survive beyond 3 years. Defining the molecular determinants underlying long-term survival is essential for insights into tumor biology and biomarker identification. We therefore investigated homogeneously treated, …
Glioblastoma (GBM) is a devastating tumor and few patients survive beyond 3 years. Defining the molecular determinants underlying long-te
The impact of predictive genetic testing for hereditary nonpolyposis colorectal cancer: three years after testing.
Collins VR, Meiser B, Ukoumunne OC, Gaff C, St John DJ, Halliday JL. Collins VR, et al. Genet Med. 2007 May;9(5):290-7. doi: 10.1097/gim.0b013e31804b45db. Genet Med. 2007. PMID: 17505206
Prophylactic surgery was rare. CONCLUSION: This report of long-term data indicates appropriate screening and improved psychological measures for non-carriers with no evidence of undue psychological distress in carriers of hereditary nonpolyposis colorectal cancer mutations …
Prophylactic surgery was rare. CONCLUSION: This report of long-term data indicates appropriate screening and improved psychological m …
Newborn screening for mucopolysaccharidoses: opinions of patients and their families.
Hayes IM, Collins V, Sahhar M, Wraith JE, Delatycki MB. Hayes IM, et al. Among authors: collins v. Clin Genet. 2007 May;71(5):446-50. doi: 10.1111/j.1399-0004.2007.00783.x. Clin Genet. 2007. PMID: 17489850
Ninety-seven percent supported the use of NBS for MPS in situations where early treatment that favorably impacts on disease outcome is available, 87% supported NBS when a severe form of MPS was diagnosed, but no treatment is available that improves the long-term outcome an …
Ninety-seven percent supported the use of NBS for MPS in situations where early treatment that favorably impacts on disease outcome is avail …
Regulation of membrane-associated prostaglandin E2 synthase 1 in pregnant sheep intrauterine tissues by glucocorticoid and estradiol.
Zhang Q, Collins V, Chakrabarty K, Wolf RF, Unno N, Howe D, Rose JC, Wu WX. Zhang Q, et al. Among authors: collins v. Endocrinology. 2006 Aug;147(8):3719-26. doi: 10.1210/en.2006-0293. Epub 2006 May 11. Endocrinology. 2006. PMID: 16690805
For gestational and labor groups, 16 pregnant ewes from 95-147 d gestational age (dGA) and four pregnant ewes at spontaneous term labor were used. The fetal glucocorticoid group, 14 pregnant ewes at 123-125 dGA with fetuses, was divided into the following groups: after sha …
For gestational and labor groups, 16 pregnant ewes from 95-147 d gestational age (dGA) and four pregnant ewes at spontaneous term lab …
Cryopreservation of viable human glioblastoma xenografts.
Goike HM, Asplund AC, Pettersson EH, Liu L, Ichimura K, Collins VP. Goike HM, et al. Among authors: collins vp. Neuropathol Appl Neurobiol. 2000 Apr;26(2):172-6. doi: 10.1046/j.1365-2990.2000.026002172.x. Neuropathol Appl Neurobiol. 2000. PMID: 10840280
The passaging and maintenance of human tumour xenografts in immune-deficient animals are expensive and labour-intensive. This study presents a protocol that permits long-term cryopreservation of viable glioblastoma xenograft tissue pieces in liquid nitrogen. ...In order to …
The passaging and maintenance of human tumour xenografts in immune-deficient animals are expensive and labour-intensive. This study presents …
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