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Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up.
Colby AH, Liu R, Doyle RP, Merting A, Zhang H, Savage N, Chu NQ, Hollister BA, McCulloch W, Burdette JE, Pearce CJ, Liu K, Oberlies NH, Colson YL, Grinstaff MW. Colby AH, et al. J Control Release. 2021 Sep 10;337:144-154. doi: 10.1016/j.jconrel.2021.07.012. Epub 2021 Jul 16. J Control Release. 2021. PMID: 34280414 Free PMC article.
Furthermore, we demonstrate good control over particle diameter, polydispersity and drug loading and the ability to sterilize the particles via filtration using this method. To facilitate long-term storage of these larger quantities of particles, we investigated six lyopro …
Furthermore, we demonstrate good control over particle diameter, polydispersity and drug loading and the ability to sterilize the particles …
Delivery of eupenifeldin via polymer-coated surgical buttresses prevents local lung cancer recurrence.
Al Subeh ZY, Chu NQ, Korunes-Miller JT, Tsai LL, Graf TN, Hung YP, Pearce CJ, Grinstaff MW, Colby AH, Colson YL, Oberlies NH. Al Subeh ZY, et al. Among authors: colby ah. J Control Release. 2021 Mar 10;331:260-269. doi: 10.1016/j.jconrel.2021.01.026. Epub 2021 Jan 21. J Control Release. 2021. PMID: 33484778 Free PMC article.
The in vitro eupenifeldin release profile depends on the number of external coating layers with the formulation of the greatest thickness demonstrating a prolonged release approaching 90 days. Similarly, the long-term cytotoxicity of eupenifeldin-loaded buttress formulatio …
The in vitro eupenifeldin release profile depends on the number of external coating layers with the formulation of the greatest thickness de …