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Eosinophilia Associated With CD3-CD4+ T Cells: Characterization and Outcome of a Single-Center Cohort of 26 Patients.
Carpentier C, Verbanck S, Schandené L, Heimann P, Trépant AL, Cogan E, Roufosse F. Carpentier C, et al. Among authors: cogan e. Front Immunol. 2020 Aug 11;11:1765. doi: 10.3389/fimmu.2020.01765. eCollection 2020. Front Immunol. 2020. PMID: 32849632 Free PMC article.
Disease manifestations were mild and did not require maintenance therapy in roughly one third of the cohort, while two thirds required long-term oral corticosteroids and/or second-line agents. Among these, interferon-alpha was the most effective treatment option with a res …
Disease manifestations were mild and did not require maintenance therapy in roughly one third of the cohort, while two thirds required long- …
[Practical approach to hypereosinophilia].
Roufosse F, Cogan E. Roufosse F, et al. Among authors: cogan e. Rev Med Brux. 2008 Sep;29(4):400-8. Rev Med Brux. 2008. PMID: 18949995 French.
Occasionally, thorough diagnostic work-up fails to identify an underlying disorder; the term hypereosinophilic syndrome is used when moderate or severe hypereosinophilia is associated with multi-organ involvement. ...
Occasionally, thorough diagnostic work-up fails to identify an underlying disorder; the term hypereosinophilic syndrome is used when …
Lymphocytic variant hypereosinophilic syndromes.
Roufosse F, Cogan E, Goldman M. Roufosse F, et al. Among authors: cogan e. Immunol Allergy Clin North Am. 2007 Aug;27(3):389-413. doi: 10.1016/j.iac.2007.07.002. Immunol Allergy Clin North Am. 2007. PMID: 17868856 Review.
Although end-organ complications of hypereosinophilia are generally benign, with predominant cutaneous manifestations, long-term prognosis is overshadowed by an increased risk of developing T-cell lymphoma, as a result of malignant transformation of aberrant T cells years …
Although end-organ complications of hypereosinophilia are generally benign, with predominant cutaneous manifestations, long-term prog …
Hypereosinophilic syndrome: lymphoproliferative and myeloproliferative variants.
Roufosse F, Goldman M, Cogan E. Roufosse F, et al. Among authors: cogan e. Semin Respir Crit Care Med. 2006 Apr;27(2):158-70. doi: 10.1055/s-2006-939519. Semin Respir Crit Care Med. 2006. PMID: 16612767 Review.
It is currently unclear whether timely therapeutic intervention in such patients could interfere with long-term progression toward malignant hematological disorders....
It is currently unclear whether timely therapeutic intervention in such patients could interfere with long-term progression toward ma …
The idiopathic hypereosinophilic syndrome: clinical presentation, pathogenesis and therapeutic strategies.
Roufosse F, Bartholomé E, Schandené L, Goldman M, Cogan E. Roufosse F, et al. Among authors: cogan e. Drugs Today (Barc). 1998 Apr;34(4):361-73. doi: 10.1358/dot.1998.34.4.485234. Drugs Today (Barc). 1998. PMID: 15010724
Correct diagnosis and management are important in order to prevent long-term complications. Furthermore, it appears that HES represents a premalignant state in some patients, and close follow-up is necessary to detect early signs of malignant transformation. ...Such patien …
Correct diagnosis and management are important in order to prevent long-term complications. Furthermore, it appears that HES represen …
The hypereosinophilic syndrome revisited.
Roufosse F, Cogan E, Goldman M. Roufosse F, et al. Among authors: cogan e. Annu Rev Med. 2003;54:169-84. doi: 10.1146/annurev.med.54.101601.152431. Epub 2001 Dec 3. Annu Rev Med. 2003. PMID: 12525672 Review.
Recent evidence suggests at least two distinct underlying hematological disorders involving myeloid and lymphoid cells, respectively. We therefore suggest that the term idiopathic should be abandoned in the classification of HES. ...
Recent evidence suggests at least two distinct underlying hematological disorders involving myeloid and lymphoid cells, respectively. We the …