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Green tea catechins decrease oxidative stress in surgical menopause-induced overactive bladder in a rat model.
Juan YS, Chuang SM, Lee YL, Long CY, Wu TH, Chang WC, Levin RM, Liu KM, Huang CH. Juan YS, et al. Among authors: chuang sm. BJU Int. 2012 Sep;110(6 Pt B):E236-44. doi: 10.1111/j.1464-410X.2012.11258.x. Epub 2012 May 28. BJU Int. 2012. PMID: 22639915
Western immunoblots were performed to determine the expressions of inflammatory markers, apoptosis-associated proteins and oxidative stress markers. RESULTS: Long-term ovariectomy significantly increased non-voiding contractions and decreased bladder compliance. ...
Western immunoblots were performed to determine the expressions of inflammatory markers, apoptosis-associated proteins and oxidative stress …
Zinc ion enhances GABA tea-mediated oxidative DNA damage.
Chuang SM, Wang HF, Hsiao CC, Cherng SH. Chuang SM, et al. J Agric Food Chem. 2012 Feb 15;60(6):1586-94. doi: 10.1021/jf2044263. Epub 2012 Feb 7. J Agric Food Chem. 2012. PMID: 22264004
Moreover, the data showed that the GABA tea extract itself (0.5-5 mg/mL) could induce DNA cleavage in a long-term exposure (48 h). EGCG, but not the GABA tea extract, enhanced H(2)O(2)-induced DNA cleavage. ...
Moreover, the data showed that the GABA tea extract itself (0.5-5 mg/mL) could induce DNA cleavage in a long-term exposure (48 h). EG …
Neuroprotection of green tea catechins on surgical menopause-induced overactive bladder in a rat model.
Juan YS, Chuang SM, Long CY, Chen CH, Levin RM, Liu KM, Huang CH. Juan YS, et al. Among authors: chuang sm. Menopause. 2012 Mar;19(3):346-54. doi: 10.1097/gme.0b013e31822d652d. Menopause. 2012. PMID: 22042325
Western immunoblots and real-time polymerase chain reaction were performed to determine M2 and M3 muscarinic cholinergic receptors (MChRs) at both protein and messenger RNA (mRNA) expressions. RESULTS: Long-term ovariectomy significantly increased non-voiding contractions, …
Western immunoblots and real-time polymerase chain reaction were performed to determine M2 and M3 muscarinic cholinergic receptors (MChRs) a …
Disturbed mitotic progression and genome segregation are involved in cell transformation mediated by nano-TiO2 long-term exposure.
Huang S, Chueh PJ, Lin YW, Shih TS, Chuang SM. Huang S, et al. Among authors: chuang sm. Toxicol Appl Pharmacol. 2009 Dec 1;241(2):182-94. doi: 10.1016/j.taap.2009.08.013. Epub 2009 Aug 18. Toxicol Appl Pharmacol. 2009. PMID: 19695278
Moreover, long-term exposure to nano-TiO2 not only increased cell survival and growth on soft agar but also the numbers of multinucleated cells and micronucleus (MN) as suggested in confocal microscopy analysis. Cell cycle phase analysis showed G2/M delay and slower cell d …
Moreover, long-term exposure to nano-TiO2 not only increased cell survival and growth on soft agar but also the numbers of multinucle …
ERK1/2 achieves sustained activation by stimulating MAPK phosphatase-1 degradation via the ubiquitin-proteasome pathway.
Lin YW, Chuang SM, Yang JL. Lin YW, et al. Among authors: chuang sm. J Biol Chem. 2003 Jun 13;278(24):21534-41. doi: 10.1074/jbc.M301854200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676937 Free article.
Taken together, these results demonstrate that activated ERK1/2 can trigger MKP-1 degradation via the ubiquitin-proteasome pathway, thus facilitating long-term activation of ERK1/2 against cytotoxicity....
Taken together, these results demonstrate that activated ERK1/2 can trigger MKP-1 degradation via the ubiquitin-proteasome pathway, thus fac …
Short-term depletion of catalase suppresses cadmium-elicited c-Jun N-terminal kinase activation and apoptosis: role of protein phosphatases.
Chuang SM, Wang IC, Hwua YS, Yang JL. Chuang SM, et al. Carcinogenesis. 2003 Jan;24(1):7-15. doi: 10.1093/carcin/24.1.7. Carcinogenesis. 2003. PMID: 12538343
Here we report that catalase is crucial for the activation of JNK by Cd. Short-term treatment of 3-amino-1,2,4-triazole (3AT), a specific catalase inhibitor, completely suppressed the Cd-elicited JNK activation, conversely, exogenous addition of catalase increased the inte …
Here we report that catalase is crucial for the activation of JNK by Cd. Short-term treatment of 3-amino-1,2,4-triazole (3AT), a spec …