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Page 1
A Core Outcome Measurement Set for Pediatric Critical Care.
Pinto NP, Maddux AB, Dervan LA, Woodruff AG, Jarvis JM, Nett S, Killien EY, Graham RJ, Choong K, Luckett PM, Heneghan JA, Biagas K, Carlton EF, Hartman ME, Yagiela L, Michelson KN, Manning JC, Long DA, Lee JH, Slomine BS, Beers SR, Hall T, Morrow BM, Meert K, Arias Lopez MDP, Knoester H, Houtrow A, Olson L, Steele L, Schlapbach LJ, Burd RS, Grosskreuz R, Butt W, Fink EL, Watson RS; POST-PICU Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN). Pinto NP, et al. Pediatr Crit Care Med. 2022 Nov 1;23(11):893-907. doi: 10.1097/PCC.0000000000003055. Epub 2022 Aug 29. Pediatr Crit Care Med. 2022. PMID: 36040097 Free PMC article.
CONCLUSIONS: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research studies to characterize PICU survivorship and enable interventional studies to target long-term outcomes after critical illness....
CONCLUSIONS: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research stud …
Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.
Christie LA, Opii WO, Head E, Araujo JA, de Rivera C, Milgram NW, Cotman CW. Christie LA, et al. Exp Gerontol. 2009 Dec;44(12):752-9. doi: 10.1016/j.exger.2009.08.012. Epub 2009 Sep 6. Exp Gerontol. 2009. PMID: 19735717 Free PMC article.
We did not observe significant positive effects on cognition. The present findings suggest that short-term supplementation with LA and ALCAR is insufficient to improve cognition in aged dogs, and that the beneficial effects of the full spectrum diet arose from either the c …
We did not observe significant positive effects on cognition. The present findings suggest that short-term supplementation with LA an …
Nutrition basics in food allergy.
Christie L. Christie L. Curr Allergy Rep. 2001 Jan;1(1):80-7. doi: 10.1007/s11882-001-0101-8. Curr Allergy Rep. 2001. PMID: 11899290 Review.
Identifying nutrition-related problems early can correct difficult situations and prevent long-term health consequences....
Identifying nutrition-related problems early can correct difficult situations and prevent long-term health consequences....
Measurement of Protein Synthesis Rate in Rat by [11C]Leucine PET Imaging: Application to the TgF344-AD Model of Alzheimer's Disease.
Bochicchio D, Christie L, Lawrence CB, Herholz K, Parker CA, Hinz R, Boutin H. Bochicchio D, et al. Among authors: christie l. Mol Imaging Biol. 2023 Jun;25(3):596-605. doi: 10.1007/s11307-022-01796-0. Epub 2022 Dec 20. Mol Imaging Biol. 2023. PMID: 36538180 Free PMC article.
Long-term memory requires stable protein synthesis and is altered in Alzheimer's disease (AD). ...
Long-term memory requires stable protein synthesis and is altered in Alzheimer's disease (AD). ...
Short-term outcomes of newborns with perinatal acidemia who are not eligible for systemic hypothermia therapy.
DuPont TL, Chalak LF, Morriss MC, Burchfield PJ, Christie L, Sánchez PJ. DuPont TL, et al. Among authors: christie l. J Pediatr. 2013 Jan;162(1):35-41. doi: 10.1016/j.jpeds.2012.06.042. Epub 2012 Aug 4. J Pediatr. 2013. PMID: 22871488 Free PMC article.
OBJECTIVE: To determine short-term outcomes of infants who had perinatal acidemia and were evaluated for hypothermia therapy but did not qualify based on a standardized neurologic examination. ...Of the latter infants classified as having mild encephalopathy, 12 (20%) expe …
OBJECTIVE: To determine short-term outcomes of infants who had perinatal acidemia and were evaluated for hypothermia therapy but did …
Long-term cognitive effects of human stem cell transplantation in the irradiated brain.
Acharya MM, Martirosian V, Christie LA, Limoli CL. Acharya MM, et al. Among authors: christie la. Int J Radiat Biol. 2014 Sep;90(9):816-20. doi: 10.3109/09553002.2014.927934. Epub 2014 Jun 25. Int J Radiat Biol. 2014. PMID: 24882389 Free PMC article.
Here, past studies have been extended to determine whether engrafted cells provide even longer-term benefits to cognition. MATERIALS AND METHODS: Athymic nude rats were cranially irradiated (10 Gy) and subjected to intrahippocampal transplantation surgery 2 days later. ... …
Here, past studies have been extended to determine whether engrafted cells provide even longer-term benefits to cognition. MATERIALS …
Multi-modal imaging of long-term recovery post-stroke by positron emission tomography and matrix-assisted laser desorption/ionisation mass spectrometry.
Henderson F, Hart PJ, Pradillo JM, Kassiou M, Christie L, Williams KJ, Boutin H, McMahon A. Henderson F, et al. Among authors: christie l. Rapid Commun Mass Spectrom. 2018 May 15;32(9):721-729. doi: 10.1002/rcm.8090. Rapid Commun Mass Spectrom. 2018. PMID: 29484723
Understanding the recovery process post-stroke is essential; however, longer-term recovery studies are lacking. In vivo positron emission tomography (PET) can image biological recovery processes, but is limited by spatial resolution and its targeted nature. ...
Understanding the recovery process post-stroke is essential; however, longer-term recovery studies are lacking. In vivo positron emis …
Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy.
Christie LA, Acharya MM, Parihar VK, Nguyen A, Martirosian V, Limoli CL. Christie LA, et al. Clin Cancer Res. 2012 Apr 1;18(7):1954-65. doi: 10.1158/1078-0432.CCR-11-2000. Epub 2012 Feb 14. Clin Cancer Res. 2012. PMID: 22338017
Advances in detection and treatment mean that many more patients are surviving long-term following diagnosis of invasive breast cancer. Thus, it is important to define the types, extent, and persistence of cognitive impairments following treatment with cytotoxic cancer dru …
Advances in detection and treatment mean that many more patients are surviving long-term following diagnosis of invasive breast cance …
Quantifying cognitive decrements caused by cranial radiotherapy.
Christie LA, Acharya MM, Limoli CL. Christie LA, et al. J Vis Exp. 2011 Oct 18;(56):3108. doi: 10.3791/3108. J Vis Exp. 2011. PMID: 22042060 Free PMC article.
These treatments however come at a cost, and nearly all cancer survivors (~11 million in the US alone as of 2006) incur some risk for developing cognitive dysfunction, with the most severe cases found in patients subjected to cranial radiotherapy (~200,000/yr) for the control of …
These treatments however come at a cost, and nearly all cancer survivors (~11 million in the US alone as of 2006) incur some risk for develo …
Long-term homocysteine exposure induces alterations in spatial learning, hippocampal signalling and synaptic plasticity.
Algaidi SA, Christie LA, Jenkinson AM, Whalley L, Riedel G, Platt B. Algaidi SA, et al. Among authors: christie la. Exp Neurol. 2006 Jan;197(1):8-21. doi: 10.1016/j.expneurol.2005.07.003. Epub 2005 Aug 10. Exp Neurol. 2006. PMID: 16095594
Bidirectional changes in basic synaptic transmission and long-term potentiation of hippocampal CA1 pyramidal cells were observed at 5, 7 and 14 weeks in both HCY groups, indicative of complex, multifactorial time- and concentration-dependent changes. ...
Bidirectional changes in basic synaptic transmission and long-term potentiation of hippocampal CA1 pyramidal cells were observed at 5 …
21 results