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Core outcome measurement set for research and clinical practice in post-COVID-19 condition (long COVID) in children and young people: an international Delphi consensus study "PC-COS Children".
Seylanova N, Chernyavskaya A, Degtyareva N, Mursalova A, Ajam A, Xiao L, Aktulaeva K, Roshchin P, Bobkova P, Aiyegbusi OL, Anbu AT, Apfelbacher C, Asadi-Pooya AA, Ashkenazi-Hoffnung L, Brackel C, Buonsenso D, de Groote W, Diaz JV, Dona D, Dunn Galvin A, Genuneit J, Goss H, Hughes SE, Jones CJ, Kuppalli K, Malone LA, McFarland S, Needham DM, Nekliudov N, Nicholson TR, Oliveira CR, Schiess N, Segal TY, Sigfrid L, Thorne C, Vijverberg S, Warner JO, Were WM, Williamson PR, Munblit D; PC-COS Children Study Group. Seylanova N, et al. Eur Respir J. 2024 Mar 14;63(3):2301761. doi: 10.1183/13993003.01761-2023. Print 2024 Mar. Eur Respir J. 2024. PMID: 38359962 Free PMC article. Review.
Early Rehabilitation in Critically ill Children: A Two Center Implementation Study.
Choong K, Fraser DD, Al-Farsi A, Awlad Thani S, Cameron S, Clark H, Cuello C, Debigaré S, Ewusie J, Kennedy K, Kho ME, Krasevich K, Martin CM, Thabane L, Nanji J, Watts C, Simpson A, Todt A, Wong J, Xie F, Vu M, Cupido C; Canadian Critical Care Trials Group. Choong K, et al. Pediatr Crit Care Med. 2024 Feb 1;25(2):92-105. doi: 10.1097/PCC.0000000000003343. Epub 2024 Jan 19. Pediatr Crit Care Med. 2024. PMID: 38240534
CONCLUSIONS: A rehabilitation bundle can improve processes of care and reduce patient sedative exposure without increasing patient discomfort, nursing workload, or harm. We did not observe an impact on short-term clinical outcomes. The efficacy of a PICU-rehabilitation bun …
CONCLUSIONS: A rehabilitation bundle can improve processes of care and reduce patient sedative exposure without increasing patient discomfor …
A Core Outcome Measurement Set for Pediatric Critical Care.
Pinto NP, Maddux AB, Dervan LA, Woodruff AG, Jarvis JM, Nett S, Killien EY, Graham RJ, Choong K, Luckett PM, Heneghan JA, Biagas K, Carlton EF, Hartman ME, Yagiela L, Michelson KN, Manning JC, Long DA, Lee JH, Slomine BS, Beers SR, Hall T, Morrow BM, Meert K, Arias Lopez MDP, Knoester H, Houtrow A, Olson L, Steele L, Schlapbach LJ, Burd RS, Grosskreuz R, Butt W, Fink EL, Watson RS; POST-PICU Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN). Pinto NP, et al. Among authors: choong k. Pediatr Crit Care Med. 2022 Nov 1;23(11):893-907. doi: 10.1097/PCC.0000000000003055. Epub 2022 Aug 29. Pediatr Crit Care Med. 2022. PMID: 36040097 Free PMC article.
CONCLUSIONS: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research studies to characterize PICU survivorship and enable interventional studies to target long-term outcomes after critical illness....
CONCLUSIONS: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research stud …
Outcomes of critically ill COVID-19 survivors and caregivers: a case study-centred narrative review.
Kho ME, Rewa OG, Boyd JG, Choong K, Stewart GCH, Herridge MS. Kho ME, et al. Among authors: choong k. Can J Anaesth. 2022 May;69(5):630-643. doi: 10.1007/s12630-022-02194-4. Epub 2022 Jan 31. Can J Anaesth. 2022. PMID: 35102495 Free PMC article. Review.
For COVID-19 patients admitted to the intensive care unit (ICU), survival may be the start of a long road to recovery. Our knowledge of the post-ICU long-term sequelae of acute respiratory distress syndrome (ARDS) and severe acute respiratory syndrome (SARS) may inform our …
For COVID-19 patients admitted to the intensive care unit (ICU), survival may be the start of a long road to recovery. Our knowledge of the …
The LiberAction Project: Implementation of a Pediatric Liberation Bundle to Screen Delirium, Reduce Benzodiazepine Sedation, and Provide Early Mobilization in a Human Resource-Limited Pediatric Intensive Care Unit.
Di Nardo M, Boldrini F, Broccati F, Cancani F, Satta T, Stoppa F, Genuini L, Zampini G, Perdichizzi S, Bottari G, Fischer M, Gawronski O, Bonetti A, Piermarini I, Recchiuti V, Leone P, Rossi A, Tabarini P, Biasucci D, Villani A, Raponi M, Cecchetti C, Choong K. Di Nardo M, et al. Among authors: choong k. Front Pediatr. 2021 Dec 8;9:788997. doi: 10.3389/fped.2021.788997. eCollection 2021. Front Pediatr. 2021. PMID: 34956989 Free PMC article.
Further pediatric studies are needed to evaluate the clinical impact of delirium, benzodiazepine-limited sedation and early mobilization protocols on patients' long-term functional outcomes and on hospital finances....
Further pediatric studies are needed to evaluate the clinical impact of delirium, benzodiazepine-limited sedation and early mobilization pro …
Long-Term Outcomes and the Post-Intensive Care Syndrome in Critically Ill Children: A North American Perspective.
Woodruff AG, Choong K. Woodruff AG, et al. Among authors: choong k. Children (Basel). 2021 Mar 24;8(4):254. doi: 10.3390/children8040254. Children (Basel). 2021. PMID: 33805106 Free PMC article. Review.
Initiatives are underway to harmonize clinical and research priorities, validate new and existing epidemiologic and patient-specific tools for the prediction or monitoring of outcomes, and define research priorities for investigators interested in long-term outcomes....
Initiatives are underway to harmonize clinical and research priorities, validate new and existing epidemiologic and patient-specific tools f …
Magnetic Resonance Imaging Findings Are Associated with Long-Term Global Neurological Function or Death after Traumatic Brain Injury in Critically Ill Children.
McInnis C, Garcia MJS, Widjaja E, Frndova H, Huyse JV, Guerguerian AM, Oyefiade A, Laughlin S, Raybaud C, Miller E, Tay K, Bigler ED, Dennis M, Fraser DD, Campbell C, Choong K, Dhanani S, Lacroix J, Farrell C, Beauchamp MH, Schachar R, Hutchison JS, Wheeler AL. McInnis C, et al. Among authors: choong k. J Neurotrauma. 2021 Sep 1;38(17):2407-2418. doi: 10.1089/neu.2020.7514. Epub 2021 May 13. J Neurotrauma. 2021. PMID: 33787327
A linear predictive model of favorable versus unfavorable long-term outcomes was significantly improved when an MRI composite score was added to clinical variables. ...Clinical MRI has prognostic value to identify children with TBI at risk of long-term unfavorable o …
A linear predictive model of favorable versus unfavorable long-term outcomes was significantly improved when an MRI composite score w …
Measurement and reporting of physical rehabilitation interventions in pediatric critical care: a scoping review.
Zorko DJ, Reid JC, Unger J, McCaskell D, Saddik M, Choong K, Kho ME. Zorko DJ, et al. Among authors: choong k. Disabil Rehabil. 2021 Nov;43(23):3417-3424. doi: 10.1080/09638288.2020.1735538. Epub 2020 Mar 17. Disabil Rehabil. 2021. PMID: 32180464 Review.
CONCLUSION: Physical rehabilitation studies in critically ill children were small, and focused on evaluating respiratory-based interventions and short-term PICU-based outcomes. Reporting of physical rehabilitation interventions was suboptimal. Use of CERT may improve desig …
CONCLUSION: Physical rehabilitation studies in critically ill children were small, and focused on evaluating respiratory-based interventions …
Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice.
Prescott HC, Iwashyna TJ, Blackwood B, Calandra T, Chlan LL, Choong K, Connolly B, Dark P, Ferrucci L, Finfer S, Girard TD, Hodgson C, Hopkins RO, Hough CL, Jackson JC, Machado FR, Marshall JC, Misak C, Needham DM, Panigrahi P, Reinhart K, Yende S, Zafonte R, Rowan KM, Angus DC. Prescott HC, et al. Among authors: choong k. Am J Respir Crit Care Med. 2019 Oct 15;200(8):972-981. doi: 10.1164/rccm.201812-2383CP. Am J Respir Crit Care Med. 2019. PMID: 31161771 Free PMC article.
However, clinical trials and guidelines have focused on shorter-term survival, so there are few data on promoting longer-term recovery. ...The top longer-term priorities were to study mechanisms of long-term morbidity through large cohort studies with …
However, clinical trials and guidelines have focused on shorter-term survival, so there are few data on promoting longer-term …
PICU-Based Rehabilitation and Outcomes Assessment: A Survey of Pediatric Critical Care Physicians.
Treble-Barna A, Beers SR, Houtrow AJ, Ortiz-Aguayo R, Valenta C, Stanger M, Chrisman M, Orringer M, Smith CM, Pollon D, Duffett M, Choong K, Watson RS, Kochanek PM, Fink EL; PICU-Rehabilitation Study Group, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, and Prevalence of Acute critical Neurological disease in children: A Global Epidemiological Assessment (PANGEA) Investigators. Treble-Barna A, et al. Among authors: choong k. Pediatr Crit Care Med. 2019 Jun;20(6):e274-e282. doi: 10.1097/PCC.0000000000001940. Pediatr Crit Care Med. 2019. PMID: 30946294 Free PMC article.
The main findings were 1) a large majority of PICU physicians reported working in institutions with no guidelines for PICU-based rehabilitation, but expressed interest in developing and implementing such guidelines; 2) despite this lack of guidelines, an overwhelming majority of …
The main findings were 1) a large majority of PICU physicians reported working in institutions with no guidelines for PICU-based rehabilitat …
23 results