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Adjuvant Systemic Therapies for Resected Stages III and IV Melanoma: A Multi-Center Retrospective Clinical Study.
Rigo R, Ding PQ, Batuyong E, Cheung WY, Walker J, Monzon JG, Cheng T. Rigo R, et al. Among authors: cheung wy. Oncologist. 2024 Jan 5;29(1):57-66. doi: 10.1093/oncolo/oyad223. Oncologist. 2024. PMID: 37648247 Free PMC article.
Similar recurrence rates were observed between anti-PD-1 immunotherapy and BRAF-targeted therapy. Long-term toxicity affected 27.4% of patients, with endocrinopathies and late-emergent immune-related adverse events being common. CONCLUSIONS: Real-world adjuvant systemic th …
Similar recurrence rates were observed between anti-PD-1 immunotherapy and BRAF-targeted therapy. Long-term toxicity affected 27.4% o …
Improving the efficiency of clinical trials in multiple sclerosis.
Marrie RA, Sormani MP, Apap Mangion S, Bovis F, Cheung WY, Cutter GR, Feys P, Hill MD, Koch MW, McCreary M, Mowry EM, Park JJ, Piehl F, Salter A, Chataway J. Marrie RA, et al. Among authors: cheung wy. Mult Scler. 2023 Aug;29(9):1136-1148. doi: 10.1177/13524585231189671. Mult Scler. 2023. PMID: 37555492 Free PMC article. Review.
RESULTS: Recommendations include increasing the use of complex innovative designs, developing biomarkers to enrich progressive MS trial populations, prioritize intermediate outcomes for further development that target therapeutic mechanisms of action other than peripherally media …
RESULTS: Recommendations include increasing the use of complex innovative designs, developing biomarkers to enrich progressive MS trial popu …
Understanding Real-World Treatment Patterns and Clinical Outcomes among Metastatic Melanoma Patients in Alberta, Canada.
O'Sullivan DE, Boyne DJ, Gogna P, Brenner DR, Cheung WY. O'Sullivan DE, et al. Among authors: cheung wy. Curr Oncol. 2023 Apr 13;30(4):4166-4176. doi: 10.3390/curroncol30040317. Curr Oncol. 2023. PMID: 37185430 Free PMC article.
Immunotherapy and targeted therapies have been shown to considerably improve long-term survival outcomes in metastatic melanoma patients. Real-world evidence on the uptake of novel therapies and outcomes for this patient population in Canada are limited. ...
Immunotherapy and targeted therapies have been shown to considerably improve long-term survival outcomes in metastatic melanoma patie …
Clinical Factors Associated with Long-Term Survival in Metastatic Melanoma Treated with Anti-PD1 Alone or in Combination with Ipilimumab.
Goutam S, Stukalin I, Ewanchuk B, Sander M, Ding PQ, Meyers DE, Heng D, Cheung WY, Cheng T. Goutam S, et al. Among authors: cheung wy. Curr Oncol. 2022 Oct 14;29(10):7695-7704. doi: 10.3390/curroncol29100608. Curr Oncol. 2022. PMID: 36290885 Free PMC article.
Statistically significant factors on univariable analysis were assessed using multivariable analysis. In total, 284 of 460 patients were identified to have short-term (<1 year) or long-term (>3 years) survival with 186 surviving <1 year and 98 surviving &gt …
Statistically significant factors on univariable analysis were assessed using multivariable analysis. In total, 284 of 460 patients were ide …
Incident Cardiovascular Disease Among Adults With Cancer: A Population-Based Cohort Study.
Paterson DI, Wiebe N, Cheung WY, Mackey JR, Pituskin E, Reiman A, Tonelli M. Paterson DI, et al. Among authors: cheung wy. JACC CardioOncol. 2022 Mar 15;4(1):85-94. doi: 10.1016/j.jaccao.2022.01.100. eCollection 2022 Mar. JACC CardioOncol. 2022. PMID: 35492824 Free PMC article.
BACKGROUND: Patients with cancer and cancer survivors are at increased risk for incident heart failure, but there are conflicting data on the long-term risk for other cardiovascular events and how such risk may vary by cancer site. ...
BACKGROUND: Patients with cancer and cancer survivors are at increased risk for incident heart failure, but there are conflicting data on th …
Mortality and Resource Use Among Individuals With Chronic Kidney Disease or Cancer in Alberta, Canada, 2004-2015.
Tonelli M, Lloyd A, Cheung WY, Hemmelgarn BR, James MT, Ravani P, Manns B, Klarenbach SW. Tonelli M, et al. Among authors: cheung wy. JAMA Netw Open. 2022 Jan 4;5(1):e2144713. doi: 10.1001/jamanetworkopen.2021.44713. JAMA Netw Open. 2022. PMID: 35076702 Free PMC article.
As expected, adjusted rates of long-term care placement and hospitalization were higher for patients with metastatic cancer than for the other 2 groups. CONCLUSIONS AND RELEVANCE: In this study, mortality, hospitalization, and likelihood of placement into long-term …
As expected, adjusted rates of long-term care placement and hospitalization were higher for patients with metastatic cancer than for …
Real World Outcomes in Patients with Advanced Melanoma Treated in Alberta, Canada: A Time-Era Based Analysis.
Rigo R, Doherty J, Koczka K, Kong S, Ding PQ, Cheng T, Cheung WY, Monzon JG. Rigo R, et al. Among authors: cheung wy. Curr Oncol. 2021 Oct 5;28(5):3978-3986. doi: 10.3390/curroncol28050338. Curr Oncol. 2021. PMID: 34677256 Free PMC article.
Immune checkpoint and MAP kinase pathway inhibitors can significantly improve long-term survival for patients with melanoma. There is limited real-world data of these regimens' effectiveness. ...
Immune checkpoint and MAP kinase pathway inhibitors can significantly improve long-term survival for patients with melanoma. There is …
Phase II multicentre, double-blind, randomised trial of ustekinumab in adolescents with new-onset type 1 diabetes (USTEK1D): trial protocol.
Gregory JW, Carter K, Cheung WY, Holland G, Bowen-Morris J, Luzio S, Dunseath G, Tree T, Yang JHM, Marwaha A, Ali MA, Bashir N, Hutchings HA, Fegan GW, Stenson R, Hiles S, Marques-Jones S, Brown A, Tatovic D, Dayan C. Gregory JW, et al. Among authors: cheung wy. BMJ Open. 2021 Oct 18;11(10):e049595. doi: 10.1136/bmjopen-2021-049595. BMJ Open. 2021. PMID: 34663658 Free PMC article.
Preservation of residual beta-cell function at diagnosis may improve glycaemic control and reduce longer-term complications.Immunotherapy has the potential to preserve endogenous beta-cell function and thereby improve metabolic control even in poorly compliant individuals. …
Preservation of residual beta-cell function at diagnosis may improve glycaemic control and reduce longer-term complications.Immunothe …
Outcomes and Healthcare Utilization Among New Persistent Opioid Users and Nonopioid Users After Curative-intent Surgery for Cancer.
Lin N, Dabas E, Quan ML, Cheung WY, Cuthbert C, Feng Y, Kong S, Sauro KM, Brenner DR, Yang L, Lu M, Xu Y. Lin N, et al. Among authors: cheung wy. Ann Surg. 2023 Apr 1;277(4):e752-e758. doi: 10.1097/SLA.0000000000005109. Epub 2021 Jul 29. Ann Surg. 2023. PMID: 34334636
OBJECTIVE: The aim of the study was to compare the health outcomes and resource use of cancer patients who were new persistent opioid users with those who were not, after undergoing curative intent surgery for cancer. BACKGROUND: Little is known about long-term health outc …
OBJECTIVE: The aim of the study was to compare the health outcomes and resource use of cancer patients who were new persistent opioid users …
Living with paradox: A qualitative study of colorectal cancer patients' experiences in managing their health after cancer treatment.
Cuthbert CA, Farragher JF, Farrer CL, Cheung WY. Cuthbert CA, et al. Among authors: cheung wy. Eur J Cancer Care (Engl). 2021 May;30(3):e13416. doi: 10.1111/ecc.13416. Epub 2021 Jan 28. Eur J Cancer Care (Engl). 2021. PMID: 33506569
OBJECTIVES: Managing one's health after colorectal cancer may present specific challenges given long-term impacts to biopsychosocial functioning. Understanding experiences of managing one's health post-treatment is important to informing patient-centred supportive care. .. …
OBJECTIVES: Managing one's health after colorectal cancer may present specific challenges given long-term impacts to biopsychosocial …
25 results