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Four-year overall survival update from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma.
Sangro B, Chan SL, Kelley RK, Lau G, Kudo M, Sukeepaisarnjaroen W, Yarchoan M, De Toni EN, Furuse J, Kang YK, Galle PR, Rimassa L, Heurgué A, Tam VC, Van Dao T, Thungappa SC, Breder V, Ostapenko Y, Reig M, Makowsky M, Paskow MJ, Gupta C, Kurland JF, Negro A, Abou-Alfa GK; HIMALAYA investigators. Sangro B, et al. Ann Oncol. 2024 Feb 19:S0923-7534(24)00049-8. doi: 10.1016/j.annonc.2024.02.005. Online ahead of print. Ann Oncol. 2024. PMID: 38382875 Free article.
Long-term survivors with STRIDE (n = 103) included participants across clinically relevant subgroups, and 57.3% (59/103) had no reported subsequent anticancer therapy. ...Results continue to support the long-term benefits of STRIDE in a diverse population, reflectiv …
Long-term survivors with STRIDE (n = 103) included participants across clinically relevant subgroups, and 57.3% (59/103) had no repor …
Microstructural Changes in the Brainstem Auditory Pathway in Children With Hearing Loss.
Moon PK, Ward KM, Din TF, Saki S, Cheng AG, Yeom KW, Ahmad IN. Moon PK, et al. Among authors: cheng ag. Otol Neurotol. 2024 Mar 1;45(3):e170-e176. doi: 10.1097/MAO.0000000000004129. Epub 2024 Feb 7. Otol Neurotol. 2024. PMID: 38361295
Longitudinal studies should assess the prognostic value of these MRI-based findings for assessing long-term outcomes and determining intervention efficacy....
Longitudinal studies should assess the prognostic value of these MRI-based findings for assessing long-term outcomes and determining …
Association between treatment-emergent hypertension and survival with lenvatinib treatment for patients with hepatocellular carcinoma in the REFLECT study.
Piscaglia F, Ikeda K, Cheng AL, Kudo M, Ikeda M, Breder V, Ryoo BY, Mody K, Ren M, Ramji Z, Sung MW. Piscaglia F, et al. Among authors: cheng al. Cancer. 2024 Apr 15;130(8):1281-1291. doi: 10.1002/cncr.35185. Epub 2024 Jan 23. Cancer. 2024. PMID: 38261521
Lenvatinib achieved promising clinical benefits in REFLECT but was associated with clinically significant treatment-emergent hypertension (CSTE-HTN, a grouped term), a common class effect of tyrosine kinase inhibitors. This post hoc analysis assessed the impact of CSTE-HTN …
Lenvatinib achieved promising clinical benefits in REFLECT but was associated with clinically significant treatment-emergent hypertension (C …
Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: Longer Term Follow-Up from the Phase 3 KEYNOTE-240 Trial.
Merle P, Kudo M, Edeline J, Bouattour M, Cheng AL, Chan SL, Yau T, Garrido M, Knox J, Daniele B, Breder V, Lim HY, Ogasawara S, Cattan S, Chao Y, Siegel AB, Martinez-Forero I, Wei Z, Liu CC, Finn RS. Merle P, et al. Among authors: cheng al. Liver Cancer. 2023 Feb 14;12(4):309-320. doi: 10.1159/000529636. eCollection 2023 Sep. Liver Cancer. 2023. PMID: 37901200 Free PMC article.
Effects of rational emotive behavior therapy on alexithymia, anxiety, depression and sleep quality of older people in nursing homes: a quasi-experimental study.
Qin N, Li J, Wu X, Zhang C, Luo Y, Dong X, Cao H, Wang S, Liu M, Xie J, Cheng AS. Qin N, et al. Among authors: cheng as. BMC Nurs. 2023 Aug 24;22(1):280. doi: 10.1186/s12912-023-01449-9. BMC Nurs. 2023. PMID: 37620805 Free PMC article.
However, it failed to significantly alleviate anxiety and depression at least in a short-term trial. Refining this intervention may have a broader, more substantial impact on future research....
However, it failed to significantly alleviate anxiety and depression at least in a short-term trial. Refining this intervention may h …
Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase-independent mechanism.
Fanunza E, Cheng AZ, Auerbach AA, Stefanovska B, Moraes SN, Lokensgard JR, Biolatti M, Dell'Oste V, Bierle CJ, Bresnahan WA, Harris RS. Fanunza E, et al. Among authors: cheng az. J Virol. 2023 Aug 31;97(8):e0078123. doi: 10.1128/jvi.00781-23. Epub 2023 Aug 11. J Virol. 2023. PMID: 37565748 Free PMC article.
HCMV has evolved strategies to overcome host-encoded antiviral defenses to achieve lytic viral DNA replication and dissemination and, under some conditions, latency and long-term persistence. Here, we show that HCMV infection causes the antiviral factor, APOBEC3B, to reloc …
HCMV has evolved strategies to overcome host-encoded antiviral defenses to achieve lytic viral DNA replication and dissemination and, under …
Longer-term Mortality and Kidney Outcomes of Participants in the Combination Antibiotics for Methicillin-Resistant Staphylococcus aureus (CAMERA2) Trial: A Post Hoc Analysis.
Legg A, Roberts MA, Davies J, Cass A, Meagher N, Sud A, Daitch V, Dishon Benattar Y, Yahav D, Paul M, Xinxin C, Ping YH, Lye D, Lee R, Robinson JO, Foo H, Tramontana AR, Bak N, Grenfell A, Rogers B, Li Y, Joshi N, O'Sullivan M, McKew G, Ghosh N, Schneider K, Holmes NE, Dotel R, Chia T, Archuleta S, Smith S, Warner MS, Titin C, Kalimuddin S, Roberts JA, Tong SYC, Davis JS; Combination Antibiotics for Methicillin-Resistant Staphylococcus aureus (CAMERA2) Study Group. Legg A, et al. Open Forum Infect Dis. 2023 Jul 3;10(7):ofad337. doi: 10.1093/ofid/ofad337. eCollection 2023 Jul. Open Forum Infect Dis. 2023. PMID: 37496601 Free PMC article.
BACKGROUND: The Combination Antibiotic Therapy for Methicillin-Resistant Staphylococcus aureus (CAMERA2) trial ceased recruitment in July 2018, noting that a higher proportion of patients in the intervention arm (combination therapy) developed acute kidney injury (AKI) compared t …
BACKGROUND: The Combination Antibiotic Therapy for Methicillin-Resistant Staphylococcus aureus (CAMERA2) trial ceased recruitment in July 20 …
Representational-mapping strategies improve learning from an online statistics textbook.
Zhang IY, Gray ME, Cheng AX, Son JY, Stigler JW. Zhang IY, et al. Among authors: cheng ax. J Exp Psychol Appl. 2023 Jun 12. doi: 10.1037/xap0000474. Online ahead of print. J Exp Psychol Appl. 2023. PMID: 37307342
Most studies so far have only attempted to help students connect between multiple representations in the lab or short-term classroom interventions, with the intervention largely separated from students' authentic learning. ...
Most studies so far have only attempted to help students connect between multiple representations in the lab or short-term classroom …
Neuropathological signatures revealed by transcriptomic and proteomic analysis in Pten-deficient mouse models.
Cheung SKK, Kwok J, Or PMY, Wong CW, Feng B, Choy KW, Chang RCC, Burbach JPH, Cheng ASL, Chan AM. Cheung SKK, et al. Among authors: cheng asl. Sci Rep. 2023 Apr 25;13(1):6763. doi: 10.1038/s41598-023-33869-7. Sci Rep. 2023. PMID: 37185447 Free PMC article.
However, primary astrocytes (ASTs) from heterozygous Pten-knockout mice were enriched in the extracellular matrix GO term, while primary cortical neurons (PCNs) were enriched in immediate-early genes. ...
However, primary astrocytes (ASTs) from heterozygous Pten-knockout mice were enriched in the extracellular matrix GO term, while prim …
276 results