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Implementation of a high sensitivity cardiac troponin I assay and risk of myocardial infarction or death at five years: observational analysis of a stepped wedge, cluster randomised controlled trial.
Lee KK, Doudesis D, Ferry AV, Chapman AR, Kimenai DM, Fujisawa T, Bularga A, Lowry MTH, Taggart C, Schulberg S, Wereski R, Tuck C, Strachan FE, Newby DE, Anand A, Shah ASV, Mills NL; High-STEACS Investigators. Lee KK, et al. Among authors: chapman ar. BMJ. 2023 Nov 27;383:e075009. doi: 10.1136/bmj-2023-075009. BMJ. 2023. PMID: 38011922 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome. ...
OBJECTIVE: To evaluate the impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients w …
MINOCA: a heterogenous group of conditions associated with myocardial damage.
Singh T, Chapman AR, Dweck MR, Mills NL, Newby DE. Singh T, et al. Among authors: chapman ar. Heart. 2021 Sep;107(18):1458-1464. doi: 10.1136/heartjnl-2020-318269. Epub 2021 Feb 10. Heart. 2021. PMID: 33568434 Review.
Myocardial infarction with non-obstructive coronary arteries (MINOCA) was first described over 80 years ago. The term has been widely and inconsistently used in clinical practice, influencing various aspects of disease classification, investigation and management. MINOCA e …
Myocardial infarction with non-obstructive coronary arteries (MINOCA) was first described over 80 years ago. The term has been widely …
Type 2 Myocardial Infarction: Evolving Approaches to Diagnosis and Risk-Stratification.
Chapman AR, Sandoval Y. Chapman AR, et al. Clin Chem. 2021 Jan 8;67(1):61-69. doi: 10.1093/clinchem/hvaa189. Clin Chem. 2021. PMID: 33418588 Free PMC article. Review.
They are increasingly encountered in clinical practice and associated with poor short- and long-term outcomes. Clinicians require novel biomarker or imaging approaches to facilitate diagnosis and risk-stratification....
They are increasingly encountered in clinical practice and associated with poor short- and long-term outcomes. Clinicians require nov …
Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.
Neumann JT, Twerenbold R, Ojeda F, Sörensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S; COMPASS-MI Study Group. Neumann JT, et al. Among authors: chapman ar. N Engl J Med. 2019 Jun 27;380(26):2529-2540. doi: 10.1056/NEJMoa1803377. N Engl J Med. 2019. PMID: 31242362
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lower likelihood of myocardial infarction and a lower short-term risk of cardiovascular events. For example, high-sensitivity troponin …
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lo …
Long-Term Outcomes in Patients With Type 2 Myocardial Infarction and Myocardial Injury.
Chapman AR, Shah ASV, Lee KK, Anand A, Francis O, Adamson P, McAllister DA, Strachan FE, Newby DE, Mills NL. Chapman AR, et al. Circulation. 2018 Mar 20;137(12):1236-1245. doi: 10.1161/CIRCULATIONAHA.117.031806. Epub 2017 Nov 17. Circulation. 2018. PMID: 29150426 Free PMC article.
BACKGROUND: Type 2 myocardial infarction and myocardial injury are common in clinical practice, but long-term consequences are uncertain. We aimed to define long-term outcomes and explore risk stratification in patients with type 2 myocardial infarction and myocardi …
BACKGROUND: Type 2 myocardial infarction and myocardial injury are common in clinical practice, but long-term consequences are uncert …
Assessment and classification of patients with myocardial injury and infarction in clinical practice.
Chapman AR, Adamson PD, Mills NL. Chapman AR, et al. Heart. 2017 Jan 1;103(1):10-18. doi: 10.1136/heartjnl-2016-309530. Epub 2016 Nov 2. Heart. 2017. PMID: 27806987 Free PMC article. Review.
However, both myocardial injury and type 2 myocardial infarction are common, occurring in more than one-third of all hospitalised patients. These patients have poor short-term and long-term outcomes with two-thirds dead in 5 years. The classification of patients wit …
However, both myocardial injury and type 2 myocardial infarction are common, occurring in more than one-third of all hospitalised patients. …
Foot orthoses and gait: a systematic review and meta-analysis of literature pertaining to potential mechanisms.
Mills K, Blanch P, Chapman AR, McPoil TG, Vicenzino B. Mills K, et al. Among authors: chapman ar. Br J Sports Med. 2010 Nov;44(14):1035-46. doi: 10.1136/bjsm.2009.066977. Epub 2009 Dec 8. Br J Sports Med. 2010. PMID: 19996330 Review.
The need for further research focusing on the role of injury, particularly in neuromotor control modification and long-term adaptation to orthoses, was highlighted....
The need for further research focusing on the role of injury, particularly in neuromotor control modification and long-term adaptatio …
Leg muscle recruitment during cycling is less developed in triathletes than cyclists despite matched cycling training loads.
Chapman AR, Vicenzino B, Blanch P, Hodges PW. Chapman AR, et al. Exp Brain Res. 2007 Aug;181(3):503-18. doi: 10.1007/s00221-007-0949-5. Epub 2007 Jun 5. Exp Brain Res. 2007. PMID: 17549464
However, interference with learning has only been studied during training periods of 1-7 days and it is not known if interference with learning continues during long-term multitask training. This study investigated muscle recruitment in highly trained triathletes, who swim …
However, interference with learning has only been studied during training periods of 1-7 days and it is not known if interference with learn …