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The impact of COVID-19 on incidence and outcomes from out-of-hospital cardiac arrest (OHCA) in Texas.
Chavez S, Huebinger R, Chan HK, Gill J, White L, Mendez D, Jarvis JL, Vithalani VD, Tannenbaum L, Al-Araji R, Bobrow B. Chavez S, et al. Among authors: chan hk. Am J Emerg Med. 2022 Jul;57:1-5. doi: 10.1016/j.ajem.2022.04.006. Epub 2022 Apr 13. Am J Emerg Med. 2022. PMID: 35468504 Free PMC article.
We aim to characterize the incidence of OHCA during the early pandemic period and the subsequent long-term period while describing changes in OHCA outcomes and survival. ...CONCLUSIONS: Our study adds state-wide evidence to the national phenomenon of long-term incre …
We aim to characterize the incidence of OHCA during the early pandemic period and the subsequent long-term period while describing ch …
Inhaled Delivery of Anti-Pseudomonal Phages to Tackle Respiratory Infections Caused by Superbugs.
Chan HK, Chang RYK. Chan HK, et al. J Aerosol Med Pulm Drug Deliv. 2022 Apr;35(2):73-82. doi: 10.1089/jamp.2021.0045. Epub 2021 Dec 30. J Aerosol Med Pulm Drug Deliv. 2022. PMID: 34967686 Free PMC article. Review.
Results: The produced phage PEV20 and PEV20-ciprofloxacin powders remained stable over long-term storage and exhibited significant bacterial killing activities in a mouse lung infection model. ...
Results: The produced phage PEV20 and PEV20-ciprofloxacin powders remained stable over long-term storage and exhibited significant ba …
Medication-related knowledge, administration practice and adherence among caregivers of chronically ill children in Malaysia.
Chew CC, Chan HK, Chang CT, Hss AS, Hassali MA. Chew CC, et al. Among authors: chan hk. BMC Pediatr. 2021 May 3;21(1):216. doi: 10.1186/s12887-021-02691-3. BMC Pediatr. 2021. PMID: 33941117 Free PMC article.
BACKGROUND: Caregivers' knowledge, practice and adherence in medication administration who care for children with chronic illness requiring long-term pharmacological treatments are factors associating with children medication safety at home. ...
BACKGROUND: Caregivers' knowledge, practice and adherence in medication administration who care for children with chronic illness requiring …
Phage cocktail powder for Pseudomonas aeruginosa respiratory infections.
Li M, Chang RYK, Lin Y, Morales S, Kutter E, Chan HK. Li M, et al. Among authors: chan hk. Int J Pharm. 2021 Mar 1;596:120200. doi: 10.1016/j.ijpharm.2021.120200. Epub 2021 Jan 21. Int J Pharm. 2021. PMID: 33486032 Free PMC article.
Phage cocktail broadens the host range compared with a single phage and minimizes the development of phage-resistant bacteria thereby promoting the long-term usefulness of inhaled phage therapy. In this study, we produced a phage cocktail powder by spray drying three Pseud …
Phage cocktail broadens the host range compared with a single phage and minimizes the development of phage-resistant bacteria thereby promot …
One-year follow-up of efficacy and cost of repeated doses versus single larger dose of intra-articular hyaluronic acid for knee osteoarthritis.
Suppan VKL, Tew MM, Wong BC, Chan HK, Chew YW, Tan CS, Nanta Kumar VK, Shafie AA, Sadashiva Rao A. Suppan VKL, et al. Among authors: chan hk. J Orthop Surg (Hong Kong). 2020 Jan-Apr;28(1):2309499019895029. doi: 10.1177/2309499019895029. J Orthop Surg (Hong Kong). 2020. PMID: 32129141 Free article. Clinical Trial.
PURPOSE: A recent 3-month randomized, open-label controlled trial found that the intra-articular hyaluronic acid injection (GO-ON()) given as a single dose of 5 mL is as effective and safe as three repeated doses of 2.5 mL in patients with knee osteoarthritis. However, the inform …
PURPOSE: A recent 3-month randomized, open-label controlled trial found that the intra-articular hyaluronic acid injection (GO-ON()) given a …
Storage stability of inhalable phage powders containing lactose at ambient conditions.
Chang RYK, Wallin M, Kutter E, Morales S, Britton W, Li J, Chan HK. Chang RYK, et al. Among authors: chan hk. Int J Pharm. 2019 Apr 5;560:11-18. doi: 10.1016/j.ijpharm.2019.01.050. Epub 2019 Jan 31. Int J Pharm. 2019. PMID: 30710661 Free PMC article.
The results demonstrate that spray dried PEV phage powders containing lactose and leucine are biologically and physically stable over long-term storage at ambient temperature. Furthermore, these spray dried phage powders were shown to be non-toxic to lung alveolar macropha …
The results demonstrate that spray dried PEV phage powders containing lactose and leucine are biologically and physically stable over long- …
Protection of hydrophobic amino acids against moisture-induced deterioration in the aerosolization performance of highly hygroscopic spray-dried powders.
Yu J, Chan HK, Gengenbach T, Denman JA. Yu J, et al. Among authors: chan hk. Eur J Pharm Biopharm. 2017 Oct;119:224-234. doi: 10.1016/j.ejpb.2017.06.023. Epub 2017 Jun 24. Eur J Pharm Biopharm. 2017. PMID: 28655664
The results broaden the understanding on the use of hydrophobic amino acids as an excipient for long-term storage of inhalation powders formulations that are hygroscopic....
The results broaden the understanding on the use of hydrophobic amino acids as an excipient for long-term storage of inhalation powde …
25th Annual Computational Neuroscience Meeting: CNS-2016.
Sharpee TO, Destexhe A, Kawato M, Sekulić V, Skinner FK, Wójcik DK, Chintaluri C, Cserpán D, Somogyvári Z, Kim JK, Kilpatrick ZP, Bennett MR, Josić K, Elices I, Arroyo D, Levi R, Rodriguez FB, Varona P, Hwang E, Kim B, Han HB, Kim T, McKenna JT, Brown RE, McCarley RW, Choi JH, Rankin J, Popp PO, Rinzel J, Tabas A, Rupp A, Balaguer-Ballester E, Maturana MI, Grayden DB, Cloherty SL, Kameneva T, Ibbotson MR, Meffin H, Koren V, Lochmann T, Dragoi V, Obermayer K, Psarrou M, Schilstra M, Davey N, Torben-Nielsen B, Steuber V, Ju H, Yu J, Hines ML, Chen L, Yu Y, Kim J, Leahy W, Shlizerman E, Birgiolas J, Gerkin RC, Crook SM, Viriyopase A, Memmesheimer RM, Gielen S, Dabaghian Y, DeVito J, Perotti L, Kim AJ, Fenk LM, Cheng C, Maimon G, Zhao C, Widmer Y, Sprecher S, Senn W, Halnes G, Mäki-Marttunen T, Keller D, Pettersen KH, Andreassen OA, Einevoll GT, Yamada Y, Steyn-Ross ML, Alistair Steyn-Ross D, Mejias JF, Murray JD, Kennedy H, Wang XJ, Kruscha A, Grewe J, Benda J, Lindner B, Badel L, Ohta K, Tsuchimoto Y, Kazama H, Kahng B, Tam ND, Pollonini L, Zouridakis G, Soh J, Kim D, Yoo M, Palmer SE, Culmone V, Bojak I, Ferrario A, Merrison-Hort R, Borisyuk R, Kim CS, Tezuka T, Joo P, Rho YA, Burt… See abstract for full author list ➔ Sharpee TO, et al. Among authors: chan hk. BMC Neurosci. 2016 Aug 18;17 Suppl 1(Suppl 1):54. doi: 10.1186/s12868-016-0283-6. BMC Neurosci. 2016. PMID: 27534393 Free PMC article.
Kiser, James H. Howard, Jr., Yi-Yuan Tang P51 The role of cerebellar short-term synaptic plasticity in the pathology and medication of downbeat nystagmus Julia Goncharenko, Neil Davey, Maria Schilstra, Volker Steuber P52 Nonlinear response of noisy neurons Sergej O. ...Gra …
Kiser, James H. Howard, Jr., Yi-Yuan Tang P51 The role of cerebellar short-term synaptic plasticity in the pathology and medication o …
How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder?
Zhou QT, Loh ZH, Yu J, Sun SP, Gengenbach T, Denman JA, Li J, Chan HK. Zhou QT, et al. Among authors: chan hk. AAPS J. 2016 Sep;18(5):1213-1224. doi: 10.1208/s12248-016-9934-x. Epub 2016 Jun 2. AAPS J. 2016. PMID: 27255350 Free PMC article.
This study has highlighted that a critical amount of azithromycin is required to sufficiently coat the colistin particles for short-term protection against moisture....
This study has highlighted that a critical amount of azithromycin is required to sufficiently coat the colistin particles for short-term …
L-Leucine as an excipient against moisture on in vitro aerosolization performances of highly hygroscopic spray-dried powders.
Li L, Sun S, Parumasivam T, Denman JA, Gengenbach T, Tang P, Mao S, Chan HK. Li L, et al. Among authors: chan hk. Eur J Pharm Biopharm. 2016 May;102:132-41. doi: 10.1016/j.ejpb.2016.02.010. Epub 2016 Mar 9. Eur J Pharm Biopharm. 2016. PMID: 26970252
In conclusion, particle surface coverage of LL can offer short-term protection against moisture on dispersion of hygroscopic powders....
In conclusion, particle surface coverage of LL can offer short-term protection against moisture on dispersion of hygroscopic powders. …
18 results