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Clinical Impact of Ceftriaxone Resistance in Escherichia coli Bloodstream Infections: A Multicenter Prospective Cohort Study.
Tamma PD, Komarow L, Ge L, Garcia-Diaz J, Herc ES, Doi Y, Arias CA, Albin O, Saade E, Miller LG, Jacob JT, Satlin MJ, Krsak M, Huskins WC, Dhar S, Shelburne SA, Hill C, Baum KR, Bhojani M, Greenwood-Quaintance KE, Schmidt-Malan SM, Patel R, Evans SR, Chambers HF, Fowler VG Jr, van Duin D; Antibacterial Resistance Leadership Group. Tamma PD, et al. Among authors: chambers hf. Open Forum Infect Dis. 2022 Oct 27;9(11):ofac572. doi: 10.1093/ofid/ofac572. eCollection 2022 Nov. Open Forum Infect Dis. 2022. PMID: 36381622 Free PMC article.
Secondary outcomes included unadjusted and adjusted differences in the proportion of 30-day mortality between CRO-R and CRO-S BSIs (-5.3% [95% CI, -10.3% to -.4%] and -1.8 [95% CI, -6.7% to 3.2%], respectively), postculture median length of stay (8 days [IQR, 5-13 days] vs 6 days …
Secondary outcomes included unadjusted and adjusted differences in the proportion of 30-day mortality between CRO-R and CRO-S BSIs (-5.3% [9 …
A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses.
Daum RS, Miller LG, Immergluck L, Fritz S, Creech CB, Young D, Kumar N, Downing M, Pettibone S, Hoagland R, Eells SJ, Boyle MG, Parker TC, Chambers HF; DMID 07-0051 Team. Daum RS, et al. Among authors: chambers hf. N Engl J Med. 2017 Jun 29;376(26):2545-2555. doi: 10.1056/NEJMoa1607033. N Engl J Med. 2017. PMID: 28657870 Free PMC article. Clinical Trial.
CONCLUSIONS: As compared with incision and drainage alone, clindamycin or TMP-SMX in conjunction with incision and drainage improves short-term outcomes in patients who have a simple abscess. This benefit must be weighed against the known side-effect profile of these antim …
CONCLUSIONS: As compared with incision and drainage alone, clindamycin or TMP-SMX in conjunction with incision and drainage improves short- …
Origins of community strains of methicillin-resistant Staphylococcus aureus.
Charlebois ED, Perdreau-Remington F, Kreiswirth B, Bangsberg DR, Ciccarone D, Diep BA, Ng VL, Chansky K, Edlin BR, Chambers HF. Charlebois ED, et al. Among authors: chambers hf. Clin Infect Dis. 2004 Jul 1;39(1):47-54. doi: 10.1086/421090. Epub 2004 Jun 1. Clin Infect Dis. 2004. PMID: 15206052 Free PMC article.
The majority (58%) of infections were caused by strains traceable to the hospital or to long-term care facilities. Injection drug use was associated with infections that were not associated with health care settings. ...
The majority (58%) of infections were caused by strains traceable to the hospital or to long-term care facilities. Injection drug use …
The changing epidemiology of Staphylococcus aureus?
Chambers HF. Chambers HF. Emerg Infect Dis. 2001 Mar-Apr;7(2):178-82. doi: 10.3201/eid0702.010204. Emerg Infect Dis. 2001. PMID: 11294701 Free PMC article. Review.
Strains of methicillin-resistant Staphylococcus aureus (MRSA), which had been largely confined to hospitals and long-term care facilities, are emerging in the community. The changing epidemiology of MRSA bears striking similarity to the emergence of penicillinase-mediated …
Strains of methicillin-resistant Staphylococcus aureus (MRSA), which had been largely confined to hospitals and long-term care facili …
A randomized clinical trial of mupirocin in the eradication of Staphylococcus aureus nasal carriage in human immunodeficiency virus disease.
Martin JN, Perdreau-Remington F, Kartalija M, Pasi OG, Webb M, Gerberding JL, Chambers HF, Täuber MG, Lee BL. Martin JN, et al. Among authors: chambers hf. J Infect Dis. 1999 Sep;180(3):896-9. doi: 10.1086/314949. J Infect Dis. 1999. PMID: 10438389 Clinical Trial.
Five days of treatment with mupirocin eliminated S. aureus nasal carriage in HIV-infected patients for several weeks; however, since the effect waned over time, intermittent dosing regimens should be considered for long-term eradication....
Five days of treatment with mupirocin eliminated S. aureus nasal carriage in HIV-infected patients for several weeks; however, since the eff …